FOXO1 and SIN3A:HDAC complex bind GCK gene promoter

Stable Identifier
R-HSA-9625101
Type
Reaction [binding]
Species
Homo sapiens
Compartment
nucleoplasm
ReviewStatus
5/5
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FOXO1 and SIN3A:HDAC complex bind GCK gene promoter
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Based on studies in mice, FOXO1 recruits transcriptional repressor SIN3A and histone deacetylases (HDACs) of the I class to the promoter of the GCK gene, encoding glucokinase (Langlet et al. 2017).
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Inferred From
Foxo1 and Sin3a:Hdac complex bind Gck gene promoter (Mus musculus)
Authored
Orlic-Milacic, M  (2018-10-23)
Reviewed
Donlon, T  (2018-10-23)
Created
Orlic-Milacic, M  (2018-10-19)
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