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HSPA8 [lysosomal lumen]
Stable Identifier
R-HSA-9625182
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
lysosomal lumen
Icon
Locations in the PathwayBrowser for interactor UniProt:P00748 F12
Expand all
Autophagy (Homo sapiens)
Chaperone Mediated Autophagy (Homo sapiens)
Unfolded substrate in LAMP2a multimeric complex binds HSPA8 (Homo sapiens)
HSPA8 [lysosomal lumen] (Homo sapiens)
External Reference Information
External Reference
UniProt:P11142 HSPA8
Gene Names
HSPA8, HSC70, HSP73, HSPA10
Chain
initiator methionine:, chain:2-646
Reference Genes
BioGPS Gene:3312 HSPA8
COSMIC (genes):HSPA8 HSPA8
CTD Gene:3312 HSPA8
dbSNP Gene:3312 HSPA8
ENSEMBL:ENSG00000109971 HSPA8
HGNC:5241 HSPA8
KEGG:hsa:3312 HSPA8
Monarch:3312 HSPA8
NCBI Gene:3312 HSPA8
OMIM:600816 HSPA8
UCSC:P11142 HSPA8
Reference Transcript
RefSeq:XM_011542798.1 HSPA8
RefSeq:NM_006597.5 HSPA8
RefSeq:NM_153201.3 HSPA8
Other Identifiers
11720916_s_at
11741210_a_at
11741211_x_at
11756622_a_at
11756623_at
11757115_s_at
11757166_at
11757167_x_at
11762261_x_at
1179_at
1180_g_at
16745525
16745561
17118860
208687_PM_x_at
208687_x_at
210338_PM_s_at
210338_s_at
221891_PM_x_at
221891_x_at
224187_PM_x_at
224187_x_at
2989994
3011035
3312
33820_g_at
3395420
3395421
3395422
3395423
3395424
3395425
3395426
3395427
3395428
3395429
3395430
3395431
3395432
3395433
3395434
3395435
3395436
3395437
3395438
3395439
3395440
3395441
3395442
3395443
3395444
3395445
3395446
3395447
3395448
3395449
3395450
3395451
3395452
3395453
3395454
3395455
3395456
3401658
4020036
4020040
4020043
4020046
40637_at
44833_s_at
73372_r_at
7952325
7952335
7952339
A_23_P24594
A_24_P177553
A_24_P287129
A_24_P295745
A_32_P13728
A_33_P3323463
A_33_P3346688
A_33_P3390758
GE79248
GO:0000082
GO:0000398
GO:0000974
GO:0001664
GO:0001786
GO:0001822
GO:0001916
GO:0001917
GO:0003723
GO:0003824
GO:0005102
GO:0005515
GO:0005524
GO:0005576
GO:0005615
GO:0005634
GO:0005654
GO:0005681
GO:0005730
GO:0005737
GO:0005764
GO:0005765
GO:0005768
GO:0005770
GO:0005773
GO:0005776
GO:0005829
GO:0005874
GO:0005882
GO:0005886
GO:0005925
GO:0006355
GO:0006397
GO:0006457
GO:0006606
GO:0006886
GO:0006913
GO:0006914
GO:0006986
GO:0007018
GO:0007519
GO:0008021
GO:0008088
GO:0008289
GO:0008380
GO:0009267
GO:0009410
GO:0009986
GO:0010045
GO:0010628
GO:0010667
GO:0014069
GO:0014823
GO:0016020
GO:0016071
GO:0016787
GO:0016887
GO:0019899
GO:0021549
GO:0022414
GO:0023026
GO:0030163
GO:0030335
GO:0030424
GO:0030425
GO:0030674
GO:0030900
GO:0031072
GO:0031410
GO:0031625
GO:0031647
GO:0031686
GO:0032279
GO:0032355
GO:0032570
GO:0032984
GO:0032991
GO:0034330
GO:0034605
GO:0034774
GO:0042026
GO:0042277
GO:0042470
GO:0042594
GO:0043025
GO:0043195
GO:0043197
GO:0043198
GO:0043202
GO:0043204
GO:0043226
GO:0043254
GO:0043531
GO:0044183
GO:0044309
GO:0044743
GO:0044788
GO:0044829
GO:0044849
GO:0045296
GO:0045471
GO:0045862
GO:0045892
GO:0046034
GO:0048018
GO:0048026
GO:0048471
GO:0048856
GO:0050766
GO:0051082
GO:0051085
GO:0051087
GO:0051726
GO:0055085
GO:0055086
GO:0055131
GO:0060090
GO:0061024
GO:0061077
GO:0061202
GO:0061635
GO:0061684
GO:0061738
GO:0061740
GO:0070062
GO:0070301
GO:0071276
GO:0071383
GO:0072318
GO:0072562
GO:0097214
GO:0098575
GO:0098684
GO:0098690
GO:0098772
GO:0098793
GO:0098794
GO:0098880
GO:0098978
GO:0099175
GO:0099523
GO:0099524
GO:0099634
GO:0101031
GO:0140104
GO:0140545
GO:0140597
GO:0140657
GO:0140662
GO:1900226
GO:1901135
GO:1902904
GO:1904589
GO:1904592
GO:1904593
GO:1904764
GO:1904813
GO:1990832
GO:1990833
GO:1990834
GO:1990836
GO:1990904
HMNXSV003014198
HMNXSV003019988
HMNXSV003023305
HMNXSV003039522
Hs.180414.3.A1_3p_a_at
ILMN_1686367
ILMN_1689294
ILMN_1754332
ILMN_2413084
PH_hs_0039202
PH_hs_0040139
RNA147239|p0343_imsncRNA763
RNA147242|p0346_imsncRNA765
TC11002390.hg
TC11002391.hg
TC11002392.hg
g11526572_3p_a_at
Participates
as an input of
Unfolded substrate in LAMP2a multimeric complex binds HSPA8 (Homo sapiens)
as a component of
HSPA8:LAMP2a multimeric complex [lysosomal membrane] (Homo sapiens)
HSPA8:Substrates for CMA [lysosomal lumen] (Homo sapiens)
HSPA8:LAMP2a multimeric complex [lysosomal membrane] (Homo sapiens)
Other forms of this molecule
HSPA8 [cytosol]
HSPA8 [late endosome lumen]
HSPA8 [clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane]
HSPA8 [plasma membrane]
HSPA8 [nucleoplasm]
HSPA8 [secretory granule lumen]
HSPA8 [extracellular region]
HSPA8 [ficolin-1-rich granule lumen]
Me3K561-HSPA8 [nucleoplasm]
Cross References
RefSeq
NP_006588.1
,
XP_011541100.1
,
NP_694881.1
Guide to Pharmacology - Targets
2543
OpenTargets
ENSG00000109971
ENSEMBL
ENSP00000227378
,
ENST00000453788
,
ENSP00000404372
,
ENST00000532636
,
ENSP00000437125
,
ENSP00000432083
,
ENST00000227378
,
ENST00000534624
ZINC - Substances
HSP7C_HUMAN
ZINC - Biogenic
HSP7C_HUMAN
ZINC target
P11142
PRO
P11142
GlyGen
P11142
PDB
3FZL
,
3FZK
,
3FZH
,
3AGZ
,
3AGY
,
5AQL
,
5AQK
,
3LDQ
,
5AQS
,
5AQT
,
3FZF
,
6B1I
,
5AQR
,
5AQI
,
5AQJ
,
5AQQ
,
4H5W
,
4H5N
,
4H5V
,
5AQO
,
4H5T
,
5AQP
,
3ESK
,
5AQG
,
5AQH
,
3M3Z
,
5AQU
,
4H5R
,
5AQF
,
6ZYJ
,
5AQM
,
6B1M
,
6B1N
,
5AQV
,
5AQN
,
4KBQ
,
3FZM
,
4HWI
ZINC - Metabolites
HSP7C_HUMAN
HPA
ENSG00000109971-HSPA8
Pharos - Targets
P11142
ZINC - Predictions - Purchasable
HSP7C_HUMAN
HMDB Protein
HMDBP13799
Interactors (160)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q9NZL4 HPBP1
0.924
15
UniProt:Q9UNE7 STUB1
1
STUB1 [cytosol]
(R-HSA-975970)
0.871
9
UniProt:O95816 BAG2
1
BAG2 [cytosol]
(R-HSA-5255445)
0.823
10
UniProt:Q5S007 LRRK2
1
LRRK2 [cytosol]
(R-HSA-5661173)
0.813
6
UniProt:P00533 EGFR
20
p-6Y-EGFR [clathrin-coated endocytic vesicle membrane]
(R-HSA-8869138)
p-5Y-EGFRvIII [plasma membrane]
(R-HSA-1248649)
EGFRvIII [plasma membrane]
(R-HSA-1214162)
p-6Y-EGFR E746_A750del;T790M [plasma membrane]
(R-HSA-1182985)
p-6Y-EGFR L858R;T790M [plasma membrane]
(R-HSA-1182984)
p-6Y-EGFR A767_V769dup [plasma membrane]
(R-HSA-1996343)
p-6Y-EGFR N771_H773dup [plasma membrane]
(R-HSA-1996342)
p-6Y-EGFR K739_I744dup [plasma membrane]
(R-HSA-1996346)
p-6Y-EGFR D770_N771insNPG [plasma membrane]
(R-HSA-1996335)
p-6Y-EGFR E746_A750del [plasma membrane]
(R-HSA-1181214)
p-6Y-EGFR L858R [plasma membrane]
(R-HSA-1173211)
p-6Y-EGFR G719S [plasma membrane]
(R-HSA-1169417)
p-6Y-EGFR L747_P753delinsS [plasma membrane]
(R-HSA-1228038)
p-6Y-EGFR L747_A750delinsP [plasma membrane]
(R-HSA-1228044)
p-6Y-EGFR L747_T751del [plasma membrane]
(R-HSA-1228041)
p-6Y-EGFR L747_S752del [plasma membrane]
(R-HSA-1228040)
p-6Y-EGFR L747_T751delinsP [plasma membrane]
(R-HSA-1228042)
p-6Y-EGFR E746_T751delinsA [plasma membrane]
(R-HSA-1228037)
p-6Y-EGFR E746_S752delinsV [plasma membrane]
(R-HSA-1228039)
p-6Y-EGFR L861Q [plasma membrane]
(R-HSA-1177541)
0.803
7
UniProt:P34932 HSPA4
2
HSPA4 [cytosol]
(R-HSA-5251946)
HSPA4 [nucleoplasm]
(R-HSA-5251998)
0.787
7
UniProt:O14976 GAK
3
GAK [cytosol]
(R-HSA-8868619)
GAK [Golgi membrane]
(R-HSA-434340)
GAK [cytoplasmic vesicle membrane]
(R-HSA-434203)
0.763
9
UniProt:Q99933 BAG1
1
BAG1 [cytosol]
(R-HSA-5255443)
0.719
13
UniProt:O00635 TRIM38
1
TRIM38 [cytosol]
(R-HSA-5624325)
0.718
6
UniProt:Q99459 CDC5L
1
CDC5L [nucleoplasm]
(R-HSA-5420887)
0.709
5
UniProt:Q3B7T1 EDRF1
0.671
6
UniProt:O75165 DNAJC13
3
DNAJC13 [azurophil granule membrane]
(R-HSA-6799140)
DNAJC13 [plasma membrane]
(R-HSA-6806255)
DNAJC13 [secretory granule membrane]
(R-HSA-6800951)
0.671
6
UniProt:O95817 BAG3
1
BAG3 [cytosol]
(R-HSA-5255451)
0.671
5
UniProt:Q9UL15 BAG5
1
BAG5 [cytosol]
(R-HSA-5255453)
0.671
9
UniProt:P54652 HSPA2
2
HSPA2 [cytosol]
(R-HSA-3371408)
HSPA2 [nucleoplasm]
(R-HSA-912480)
0.671
6
UniProt:Q15428 SF3A2
1
SF3A2 [nucleoplasm]
(R-HSA-71964)
0.669
4
UniProt:Q15750 TAB1
6
TAB1 [cytosol]
(R-HSA-167923)
TAB1 [endosome membrane]
(R-HSA-450238)
TAB1(1-444) [cytosol]
(R-HSA-9729751)
TAB1(1-132) [cytosol]
(R-HSA-9729698)
TAB1(133-504) [cytosol]
(R-HSA-9729724)
TAB1(445-504) [cytosol]
(R-HSA-9729691)
0.669
3
UniProt:P10636 MAPT
3
MAPT(422-758) [cytosol]
(R-HSA-350642)
MAPT(2-421) [cytosol]
(R-HSA-350628)
MAPT [cytosol]
(R-HSA-201574)
0.667
6
UniProt:P54253 ATX1
0.666
13
UniProt:P05067 APP
20
APP(672-713) [extracellular region]
(R-HSA-879340)
APP(672-711) [cytosol]
(R-HSA-877188)
APP(672-711) [extracellular region]
(R-HSA-976740)
APP [endoplasmic reticulum lumen]
(R-HSA-8956696)
p-APP [endoplasmic reticulum lumen]
(R-HSA-8957012)
APP(18-770) [endosome lumen]
(R-HSA-5229077)
APP(672-711) [endosome lumen]
(R-HSA-6783333)
APP(672-713) [endosome lumen]
(R-HSA-5692993)
APP(672-770) [endosome lumen]
(R-HSA-9010082)
APP(712-770) [endosome lumen]
(R-HSA-6783331)
APP(714-770) [endosome lumen]
(R-HSA-6783325)
APP(18-671) [endosome lumen]
(R-HSA-5693003)
APP(18-770) [plasma membrane]
(R-HSA-9010038)
APP(18-770) [Golgi lumen]
(R-HSA-8871509)
APP(688-770) [plasma membrane]
(R-HSA-9010028)
APP(18-687) [extracellular region]
(R-HSA-9010033)
APP(18-770) [platelet alpha granule lumen]
(R-HSA-139835)
APP(18-770) [extracellular region]
(R-HSA-49335)
APP-C99 [cytosol]
(R-HSA-9617603)
APP(18-770) [trans-Golgi network membrane]
(R-HSA-5229136)
0.666
8
UniProt:P42858 HTT
1
HTT [nucleoplasm]
(R-HSA-9023590)
0.666
14
UniProt:O95429 BAG4
3
BAG4 [cytosol]
(R-HSA-5212670)
BAG4(1-126)-p-8Y-FGFR1(208-822) fusion [plasma membrane]
(R-HSA-8853156)
BAG4(1-126)-FGFR1(208-822) fusion [plasma membrane]
(R-HSA-8853157)
0.666
6
UniProt:Q8TDR0 TRAF3IP1
2
TRAF3IP1 [ciliary tip]
(R-HSA-5625404)
TRAF3IP1 [cilium]
(R-HSA-5617603)
0.664
5
UniProt:O15273 TCAP
1
TCAP [cytosol]
(R-HSA-390571)
0.659
4
UniProt:Q99592 ZBT18
0.643
3
UniProt:Q96CP2 FWCH2
0.643
3
UniProt:Q9NVT9 ARMC1
0.643
4
UniProt:P42684 ABL2
1
ABL2 [cytosol]
(R-HSA-375998)
0.643
3
UniProt:P36507 MAP2K2
12
p-S222,S226-MAP2K2 [cytosol]
(R-HSA-169292)
MAP2K2 [cytosol]
(R-HSA-59504)
p-S,T-MAP2K2 [cytosol]
(R-HSA-109848)
MAP2K2 N126D [cytosol]
(R-HSA-9652079)
MAP2K2 L46F [cytosol]
(R-HSA-9652076)
MAP2K2 F57C [cytosol]
(R-HSA-9652073)
MAP2K2 Y134C [cytosol]
(R-HSA-9652089)
MAP2K2 V35M [cytosol]
(R-HSA-9652086)
MAP2K2 P128Q [cytosol]
(R-HSA-9652082)
MAP2K2 C125S [cytosol]
(R-HSA-9652070)
MAP2K2(11-400) [cytosol]
(R-HSA-5211337)
MAP2K2(1-10) [cytosol]
(R-HSA-5211334)
0.643
5
UniProt:P00338 LDHA
2
LDHA [cytosol]
(R-HSA-70502)
PolyUb-LDHA [cytosol]
(R-HSA-9861549)
0.639
4
UniProt:P13569 CFTR
17
misfolded CFTR [endoplasmic reticulum membrane]
(R-HSA-8868730)
CFTR [endoplasmic reticulum membrane]
(R-HSA-8866837)
CFTR [plasma membrane]
(R-HSA-383188)
CFTR N1303K [plasma membrane]
(R-HSA-5678983)
CFTR F508del [plasma membrane]
(R-HSA-5678978)
CFTR W1282* [plasma membrane]
(R-HSA-5678976)
CFTR G551D [plasma membrane]
(R-HSA-5678977)
CFTR G542* [plasma membrane]
(R-HSA-5678986)
ub-CFTR F508del [endoplasmic reticulum membrane]
(R-HSA-8866842)
ub-CFTR F508del [cytosol]
(R-HSA-8866838)
CFTR F508del [endoplasmic reticulum membrane]
(R-HSA-8866834)
PolyUb-CFTR [endosome membrane]
(R-HSA-6782976)
CFTR [endosome membrane]
(R-HSA-6782965)
CFTR [Golgi-associated vesicle membrane]
(R-HSA-5627079)
CFTR [lysosomal membrane]
(R-HSA-5627279)
PolyUb-CFTR [plasma membrane]
(R-HSA-8867595)
PolyUb-CFTR [clathrin-coated endocytic vesicle membrane]
(R-HSA-8869104)
0.615
22
UniProt:P38260 FES1
0.61
4
UniProt:Q92731 ESR2
5
ESR2 [cytosol]
(R-HSA-9020970)
ESR2 [nucleoplasm]
(R-HSA-446165)
Me-PalmS-ESR2 [plasma membrane]
(R-HSA-9637787)
PalmS-ESR2 [plasma membrane]
(R-HSA-9021059)
PalmS-ESR2 [cytosol]
(R-HSA-9020979)
0.597
3
UniProt:P03372 ESR1
10
ESR1 [cytosol]
(R-HSA-9020968)
ESR1 [nucleoplasm]
(R-HSA-446168)
Me260-PalmS-ESR1 [plasma membrane]
(R-HSA-9637788)
PalmS-ESR1 [plasma membrane]
(R-HSA-9021057)
PalmS-ESR1 [cytosol]
(R-HSA-9020974)
Me260-ESR1 [cytosol]
(R-HSA-9632177)
p-S167-ESR1 [cytosol]
(R-HSA-9841254)
p-S167-ESR1 [nucleoplasm]
(R-HSA-9841867)
monoSUMO1-5K-ESR1 [nucleoplasm]
(R-HSA-4090302)
p-S118-ESR1 [nucleoplasm]
(R-HSA-9024210)
0.597
3
UniProt:P60709 ACTB
5
ACTB [plasma membrane]
(R-HSA-196016)
ACTB [lysosomal membrane]
(R-HSA-196160)
ACTB [cytosol]
(R-HSA-201861)
ACTB [nucleoplasm]
(R-HSA-3321990)
Unfolded ACTB [cytosol]
(R-HSA-390462)
0.573
2
UniProt:Q99IB8-PRO_0000045603
0.57
3
UniProt:Q9BQC3 DPH2
1
DPH2 [cytosol]
(R-HSA-5358368)
0.569
4
UniProt:Q99615 DNAJC7
2
DNAJC7 [nucleoplasm]
(R-HSA-5255408)
DNAJC7 [cytosol]
(R-HSA-5252099)
0.569
3
UniProt:Q9H4A3 WNK1
1
WNK1 [cytosol]
(R-HSA-2672391)
0.569
5
UniProt:Q9BZG8 DPH1
1
DPH1 [cytosol]
(R-HSA-5358384)
0.569
4
UniProt:O95757 HSPA4L
2
HSPA4L [cytosol]
(R-HSA-5251943)
HSPA4L [nucleoplasm]
(R-HSA-5252053)
0.569
4
UniProt:P10636-8 MAPT
3
MAPT-8 [cytosol]
(R-HSA-9619519)
p-S262,S356,S396-MAPT-8 [cytosol]
(R-HSA-9619521)
p-S199,S202,S262,S396,S404,S409,T181,T231-MAPT-8 [cytosol]
(R-HSA-9836400)
0.569
11
UniProt:Q8IZP0 ABI1
2
p-5S-ABI1 [cytosol]
(R-HSA-2029034)
ABI1 [cytosol]
(R-HSA-1671643)
0.564
2
UniProt:Q9BQI3 EIF2AK1
3
p-T-EIF2AK1 [cytosol]
(R-HSA-9648892)
p-T,T486,T488-EIF2AK1 [cytosol]
(R-HSA-9648894)
EIF2AK1 [cytosol]
(R-HSA-9840382)
0.564
2
UniProt:Q99558 MAP3K14
5
Active NIK [cytosol]
(R-HSA-5607646)
MAP3K14 [cytosol]
(R-HSA-168189)
p-MAP3K14 [cytosol]
(R-HSA-168187)
K48polyUb-NIK [cytosol]
(R-HSA-5668525)
p-T559-MAP3K14 [cytosol]
(R-HSA-5668531)
0.564
3
UniProt:P05412 JUN
4
JUN [nucleoplasm]
(R-HSA-450250)
p-S63,S73-JUN [nucleoplasm]
(R-HSA-450237)
JUN [cytosol]
(R-HSA-168194)
p-S63,S73-JUN [cytosol]
(R-HSA-8868682)
0.564
3
UniProt:Q14164 IKBKE
5
IKBKE [cytosol]
(R-HSA-450225)
p-S172-IKBKE [cytosol]
(R-HSA-450278)
K63polyUb-K30,K401-IKBKE [cytosol]
(R-HSA-9730436)
p-S172-IKBKE [nucleoplasm]
(R-HSA-4755521)
monoSUMO1-K231-p-S172-IKBKE [nucleoplasm]
(R-HSA-4755535)
0.564
2
UniProt:P50552 VASP
1
VASP [cytosol]
(R-HSA-446323)
0.564
2
UniProt:P57723 PCBP4
1
PCBP4 [cytosol]
(R-HSA-6803382)
0.564
2
UniProt:Q9H6T0 ESRP2
1
ESRP2 [nucleoplasm]
(R-HSA-6803474)
0.564
2
UniProt:Q9ULK5 VANGL2
2
VANGL2 [plasma membrane]
(R-HSA-3965373)
pS5,S82,S84-VANGL2 [plasma membrane]
(R-HSA-4551547)
0.564
2
UniProt:P01308-PRO_0000015820 INS
0.558
2
UniProt:P10636-6 MAPT
0.558
3
UniProt:P01893 HLA-H
8
HLA-H [phagocytic vesicle membrane]
(R-HSA-8855901)
HLA-H [recycling endosome membrane]
(R-HSA-8863855)
HLA-H [early endosome membrane]
(R-HSA-8855898)
HLA-H [ER to Golgi transport vesicle membrane]
(R-HSA-8855892)
HLA-H [Golgi membrane]
(R-HSA-8855895)
HLA-H [plasma membrane]
(R-HSA-6806266)
HLA-H [azurophil granule membrane]
(R-HSA-6799339)
HLA-H [lumenal side of endoplasmic reticulum membrane]
(R-HSA-8855907)
0.558
2
UniProt:O60260-5 PRKN
0.556
9
UniProt:P41220 RGS2
1
RGS2 [plasma membrane]
(R-HSA-939787)
0.553
2
UniProt:O43765 SGTA
1
SGTA [cytosol]
(R-HSA-5423595)
0.547
2
UniProt:Q8N163 CCAR2
2
DBC1 [nucleoplasm]
(R-HSA-3371479)
p-T454-DBC1 [nucleoplasm]
(R-HSA-3371569)
0.547
2
UniProt:Q96MN9 ZN488
0.527
3
UniProt:Q9H9A6 LRC40
0.527
2
UniProt:Q00341 HDLBP
1
HDLBP [plasma membrane]
(R-HSA-8858026)
0.527
2
UniProt:Q96BH1 RNF25
1
RNF25 [cytosol]
(R-HSA-975976)
0.527
2
UniProt:P30679 GNA15
1
GNA15 [plasma membrane]
(R-HSA-167450)
0.527
2
UniProt:Q9Y2I8 WDR37
0.527
5
UniProt:Q6ZMN8 CCNI2
0.527
2
UniProt:Q15555 MARE2
0.527
3
UniProt:P0DPA2 VSIG8
0.527
2
UniProt:Q9BXA7 TSSK1
0.527
2
UniProt:Q8IVL6 P3H3
1
LEPREL2 [endoplasmic reticulum lumen]
(R-HSA-1650821)
0.527
2
UniProt:Q5TEC6 H37
0.527
2
UniProt:P40121 CAPG
0.527
2
UniProt:Q9Y6J9 TAF6L
1
TAF6L [nucleoplasm]
(R-HSA-212393)
0.527
2
UniProt:Q53H47 SETMR
0.527
2
UniProt:P68871 HBB
8
HBB [lysosomal lumen]
(R-HSA-9625193)
HBB [cytosol]
(R-HSA-1008196)
HBB [late endosome lumen]
(R-HSA-9631108)
HBB [tertiary granule lumen]
(R-HSA-6800191)
HBB [extracellular region]
(R-HSA-2168872)
HBB [ficolin-1-rich granule lumen]
(R-HSA-6801015)
HBB [endocytic vesicle lumen]
(R-HSA-2230936)
CO-H+-HBB [cytosol]
(R-HSA-1237013)
0.527
2
UniProt:Q9UNU6 CYP8B1
1
CYP8B1 [endoplasmic reticulum membrane]
(R-HSA-192012)
0.527
2
UniProt:Q96FZ2 HMCES
0.527
3
UniProt:P57076 CF298
0.527
3
UniProt:Q7L4E1 MIGA2
1
MIGA2 [mitochondrial outer membrane]
(R-HSA-8954402)
0.527
2
UniProt:Q8IYG6 LRC56
0.527
3
UniProt:Q8TDN2 KCNV2
1
KCNV2 [plasma membrane]
(R-HSA-977505)
0.527
2
UniProt:Q9H7S9 ZNF703
1
ZNF703 [nucleoplasm]
(R-HSA-2454149)
0.527
2
UniProt:P53367 ARFP1
0.527
3
UniProt:Q8N4P2 IFT70B
2
TTC30B [ciliary tip]
(R-HSA-5637970)
TTC30B [cilium]
(R-HSA-5637971)
0.527
2
UniProt:Q8N239 KLH34
0.527
3
UniProt:Q9H6A0 DENND2D
1
DENND2D [cytosol]
(R-HSA-8876071)
0.527
2
UniProt:P62993 GRB2
1
GRB2 [cytosol]
(R-HSA-8983328)
0.527
3
UniProt:Q6UXT9 ABH15
0.527
3
UniProt:P31350 RRM2
1
RRM2 [cytosol]
(R-HSA-73639)
0.527
2
UniProt:Q6P158 DHX57
0.527
3
UniProt:A2VCK2 DCD2B
0.527
2
UniProt:Q6ZMP0 THSD4
3
THSD4 [endoplasmic reticulum lumen]
(R-HSA-5173065)
glc-fuc-THSD4 [endoplasmic reticulum lumen]
(R-HSA-5173066)
O-fuc-THSD4 [endoplasmic reticulum lumen]
(R-HSA-5173088)
0.527
2
UniProt:Q2TAL8 QRIC1
0.527
3
UniProt:Q9H6K1 ILRUN
0.527
3
UniProt:Q9NVX7 KBTB4
0.527
2
UniProt:P55039 DRG2
2
3OHK21-DRG2 [cytosol]
(R-HSA-9629595)
DRG2 [cytosol]
(R-HSA-9629597)
0.527
2
UniProt:P61011 SRP54
1
SRP54 [cytosol]
(R-HSA-264977)
0.527
2
UniProt:Q309B1 TR16L
0.527
2
UniProt:Q96E22 NUS1
1
NUS1 [endoplasmic reticulum membrane]
(R-HSA-6806946)
0.527
3
UniProt:Q8N4N3 KLH36
0.527
2
UniProt:Q9NZV8 KCND2
1
KCND2 [plasma membrane]
(R-HSA-977453)
0.527
2
UniProt:Q38SD2 LRRK1
0.527
2
UniProt:Q13620 CUL4B
2
CUL4B [nucleoplasm]
(R-HSA-975973)
G76-NEDD8-K859-CUL4B [nucleoplasm]
(R-HSA-8952522)
0.527
2
UniProt:Q9NYQ3 HAO2
2
HAO2 [cytosol]
(R-HSA-9033093)
HAO2 [peroxisomal matrix]
(R-HSA-6787806)
0.527
2
UniProt:Q6JEL2 KLH10
0.527
3
UniProt:Q96DF8 ESS2
0.527
2
UniProt:Q9NX65 ZSCAN32
1
ZSCAN32 [nucleoplasm]
(R-HSA-1247547)
0.527
2
UniProt:P56555 DSCR4
0.527
2
UniProt:Q8N831 TSYL6
0.527
2
UniProt:Q14249 NUCG
0.527
3
UniProt:Q15459 SF3A1
1
SF3A1 [nucleoplasm]
(R-HSA-71962)
0.527
3
UniProt:P69905 HBA1
4
HBA1 [extracellular region]
(R-HSA-2168862)
HBA1 [endocytic vesicle lumen]
(R-HSA-2230966)
HBA1 [cytosol]
(R-HSA-1008268)
CO-H+-HBA1 [cytosol]
(R-HSA-1237026)
0.527
2
UniProt:Q9UJ71 CD207
3
CD207 [early endosome membrane]
(R-HSA-1236852)
CD207 [clathrin-coated endocytic vesicle membrane]
(R-HSA-1236762)
CD207 [plasma membrane]
(R-HSA-1216519)
0.527
2
UniProt:Q99742 NPAS1
0.527
3
UniProt:Q9H0B6 KLC2
1
KLC2 [cytosol]
(R-HSA-983191)
0.527
2
UniProt:P63092 GNAS
1
GNAS2 [plasma membrane]
(R-HSA-164387)
0.527
2
UniProt:Q09472 EP300
5
EP300 [nucleoplasm]
(R-HSA-381325)
p-S,T-EP300 [nucleoplasm]
(R-HSA-8878072)
FOXO4-S-S-EP300 [nucleoplasm]
(R-HSA-9617691)
Foxo4-S-S-EP300 [nucleoplasm]
(R-HSA-9617720)
monoSUMO1-K1020,1024-EP300 [nucleoplasm]
(R-HSA-3899306)
0.527
2
UniProt:Q9Y5Z7 HCFC2
1
HCFC2 [nucleoplasm]
(R-HSA-9821232)
0.527
3
UniProt:P22612 PRKACG
3
PRKACG [ciliary base]
(R-HSA-5610405)
PRKACG [cytosol]
(R-HSA-57848)
PRKACG [nucleoplasm]
(R-HSA-111938)
0.527
2
UniProt:Q12874 SF3A3
1
SF3A3 [nucleoplasm]
(R-HSA-71966)
0.527
2
UniProt:Q2T9J0 TYSND1
4
TYSND1(111-566) [peroxisomal matrix]
(R-HSA-9033589)
TYSND1(1-110) [peroxisomal matrix]
(R-HSA-9033587)
TYSND1 [peroxisomal matrix]
(R-HSA-8933309)
TYSND1 [cytosol]
(R-HSA-9033586)
0.527
2
UniProt:Q12948 FOXC1
1
FOXC1 [nucleoplasm]
(R-HSA-3927815)
0.527
2
UniProt:Q7Z434 MAVS
2
MAVS [mitochondrial outer membrane]
(R-HSA-913730)
K48polyUb-MAVS [mitochondrial outer membrane]
(R-HSA-983463)
0.527
3
UniProt:Q13418 ILK
1
ILK [cytosol]
(R-HSA-432864)
0.527
2
UniProt:P49674 CSNK1E
2
CSNK1E [cytosol]
(R-HSA-205877)
CSNK1E [nucleoplasm]
(R-HSA-421306)
0.527
3
UniProt:P07900 HSP90AA1
8
HSP90AA1 [lysosomal lumen]
(R-HSA-9622850)
HSP90AA1 [cytosol]
(R-HSA-192864)
HSP90AA1 [nucleoplasm]
(R-HSA-5082401)
HSP90AA1 [plasma membrane]
(R-HSA-534996)
HSP90AA1 [secretory granule lumen]
(R-HSA-6801515)
HSP90AA1 [extracellular region]
(R-HSA-3221946)
HSP90AA1 [ficolin-1-rich granule lumen]
(R-HSA-6801470)
HSP90AA1 [endocytic vesicle lumen]
(R-HSA-3221912)
0.527
2
UniProt:O15530 PDPK1
3
p-S241-PDPK1 [cytosol]
(R-HSA-9860799)
PDPK1 [cytosol]
(R-HSA-202210)
PDPK1 [plasma membrane]
(R-HSA-61459)
0.527
4
UniProt:Q8WXB1 METTL21A
1
METTL21A [nucleoplasm]
(R-HSA-8876682)
0.527
3
UniProt:Q9BYJ1 ALOXE3
1
ALOXE3 [cytosol]
(R-HSA-8942204)
0.527
2
UniProt:A6NED2 RCCD1
2
3OHR141-RCCD1 [cytosol]
(R-HSA-9629871)
RCCD1 [cytosol]
(R-HSA-9629873)
0.527
2
UniProt:Q9Y6D9 MAD1L1
1
MAD1L1 [cytosol]
(R-HSA-141433)
0.527
2
UniProt:Q9Y6A5 TACC3
1
TACC3 [cytosol]
(R-HSA-2160956)
0.527
2
UniProt:Q96SI1 KCTD15
1
KCTD15 [nucleoplasm]
(R-HSA-8864337)
0.527
2
UniProt:Q7Z6Z6 PNPLA5
1
PNPLA5 [cytosol]
(R-HSA-8848346)
0.527
3
UniProt:O75496 GMNN
2
GMNN [nucleoplasm]
(R-HSA-113554)
PolyUb-GMNN [nucleoplasm]
(R-HSA-68585)
0.527
2
UniProt:Q53H54 TRMT12
1
TRMT12 [cytoplasm]
(R-HSA-6782860)
0.527
2
UniProt:Q14186 TFDP1
1
TFDP1 [nucleoplasm]
(R-HSA-68652)
0.527
2
UniProt:Q15813 TBCE
1
TBCE [cytosol]
(R-HSA-379539)
0.527
2
UniProt:P27540 ARNT
1
ARNT [nucleoplasm]
(R-HSA-1234098)
0.527
2
UniProt:P0DTC9 N
13
SUMO1-K62-ADPr-p-11S,2T-metR95,177-N [cytosol]
(R-COV-9729340)
SUMO1-K62-ADPr-p-11S,2T-metR95,177-N [endoplasmic reticulum-Golgi intermediate compartment membrane]
(R-COV-9729341)
ADPr-p-11S,2T-metR95,177-N [cytosol]
(R-COV-9729275)
p-11S,2T-metR95,177-N [cytosol]
(R-COV-9729308)
p-11S,2T-N [cytosol]
(R-COV-9729264)
p-8S,2T-N [cytosol]
(R-COV-9729277)
p-8S-N [cytosol]
(R-COV-9729335)
p-S188,206-N [cytosol]
(R-COV-9729324)
N [cytosol]
(R-COV-9694300)
SUMO1-K62,ADPr-,p-11S,2T,met-R95,177,Ac-K375-N [cytosol]
(R-COV-9756489)
N [plasma membrane]
(R-COV-9694356)
SUMO1-K62-ADPr-p-11S,2T-metR95,177-N [nucleolus]
(R-COV-9729339)
SUMO1-K62-ADPr-p-11S,2T-metR95,177-N [plasma membrane]
(R-COV-9729325)
0.527
3
UniProt:P02768 ALB
7
ALB(19-609) [extracellular region]
(R-HSA-114609)
ALB [platelet alpha granule lumen]
(R-HSA-49865)
salicyl-ALB [extracellular region]
(R-HSA-9750694)
acetyl-ALB [extracellular region]
(R-HSA-9749660)
ALB [extracellular region]
(R-HSA-194115)
p-ALB [endoplasmic reticulum lumen]
(R-HSA-8956930)
ALB [endoplasmic reticulum lumen]
(R-HSA-8956690)
0.527
2
UniProt:Q6NZI2 PTRF
2
PTRF [nucleoplasm]
(R-HSA-74981)
CAVIN1 [plasma membrane]
(R-HSA-9714278)
0.527
2
UniProt:Q99439 CNN2
3
CNN2 [tertiary granule lumen]
(R-HSA-6800942)
CNN2 [extracellular region]
(R-HSA-6806300)
CNN2 [specific granule lumen]
(R-HSA-6799532)
0.527
2
UniProt:P15056 BRAF
20
p-S,T-BRAF [cytosol]
(R-HSA-169856)
BRAF(1-380)-MACF1(600-7388)fusion [cytosol]
(R-HSA-6802402)
p-BRAF(1-380)-MACF1(600-7388) fusion [cytosol]
(R-HSA-6802536)
BRAF E501G [cytosol]
(R-HSA-9651132)
BRAF D594N [cytosol]
(R-HSA-6802299)
BRAF D638E [cytosol]
(R-HSA-9651125)
BRAF G596R [cytosol]
(R-HSA-6802385)
BRAF D594V [cytosol]
(R-HSA-6802305)
BRAF G596V [cytosol]
(R-HSA-9651138)
BRAF G466E [cytosol]
(R-HSA-6802374)
BRAF D594G [cytosol]
(R-HSA-6802295)
BRAF L505H [cytosol]
(R-HSA-9648845)
BRAF F595L [cytosol]
(R-HSA-6802316)
BRAF L597V [cytosol]
(R-HSA-6802397)
BRAF G464E [cytosol]
(R-HSA-6802369)
BRAF N581D [cytosol]
(R-HSA-9651152)
BRAF E586K [cytosol]
(R-HSA-6802308)
BRAF V600K [cytosol]
(R-HSA-6802502)
BRAF A246P [cytosol]
(R-HSA-9651123)
BRAF G469V [cytosol]
(R-HSA-9648620)
0.527
2
UniProt:P00748 F12
11
factor XII [plasma membrane]
(R-HSA-158214)
factor XIIa light chain [extracellular region]
(R-HSA-158320)
factor XIIa heavy chain [extracellular region]
(R-HSA-158285)
F12 T328K [plasma membrane]
(R-HSA-9653238)
F12 T328R [plasma membrane]
(R-HSA-9653226)
F12 T328R(20-328) [extracellular region]
(R-HSA-9653225)
F12 T328K(20-328) [extracellular region]
(R-HSA-9653230)
F12 T328K (329-615) [extracellular region]
(R-HSA-9653252)
F12 T328R (329-615) [extracellular region]
(R-HSA-9653243)
F12 T328R (373-615) [extracellular region]
(R-HSA-9655055)
F12 T328K (373-615) [extracellular region]
(R-HSA-9655053)
0.527
3
UniProt:Q9Y490 TLN1
4
TLN1 [extracellular region]
(R-HSA-350693)
TLN1(434-2541) [cytosol]
(R-HSA-9855156)
TLN1(1-433) [cytosol]
(R-HSA-9855031)
TLN1 [cytosol]
(R-HSA-350713)
0.527
2
UniProt:P03485 M
6
M1 [plasma membrane]
(R-FLU-195782)
M1 [extracellular region]
(R-FLU-169241)
M1 [endocytic vesicle membrane]
(R-FLU-189168)
M1 [endosome lumen]
(R-FLU-189155)
M1 [cytosol]
(R-FLU-169073)
M1 [nucleoplasm]
(R-FLU-186959)
0.524
4
UniProt:Q9NQ11 ATP13A2
1
ATP13A2 [lysosomal lumen]
(R-HSA-939762)
0.508
2
UniProt:Q8AZK7 EBNA5
0.499
3
UniProt:P14598 NCF1
4
p-S345-NCF1 [cytosol]
(R-HSA-9626824)
p-6S-NCF1 [cytosol]
(R-HSA-9626854)
NCF1 [cytosol]
(R-HSA-1222296)
p-6S-NCF1 [phagolysosome]
(R-HSA-1996220)
0.499
2
UniProt:P61764 STXBP1
2
STXBP1 [plasma membrane]
(R-HSA-2980862)
STXBP1 [cytosol]
(R-HSA-6794256)
0.499
2
UniProt:Q15131 CDK10
0.499
2
UniProt:P40692 MLH1
3
MLH1 [nucleoplasm]
(R-HSA-912495)
MLH1 H329P [nucleoplasm]
(R-HSA-5444512)
MLH1 S252* [nucleoplasm]
(R-HSA-5444526)
0.499
2
UniProt:Q9GZX7 AICDA
1
AICDA [nucleoplasm]
(R-HSA-452477)
0.499
2
UniProt:P32121 ARRB2
3
ARRB2 [cytosol]
(R-HSA-416464)
PolyUb-ARRB2 [cytosol]
(R-HSA-6783000)
ARRB2 [endocytic vesicle membrane]
(R-HSA-9910881)
0.499
4
UniProt:P49407 ARRB1
6
ARRB1 [cytosol]
(R-HSA-264470)
PolyUb-ARRB1 [cytosol]
(R-HSA-6783186)
ARRB1 [endocytic vesicle membrane]
(R-HSA-9910882)
ARRB1 [lysosomal membrane]
(R-HSA-432701)
ARRB1 [Golgi membrane]
(R-HSA-350831)
ARRB1 [cytoplasmic vesicle membrane]
(R-HSA-351187)
0.499
4
UniProt:Q99IB8-PRO_0000045599
0.488
2
UniProt:O15013 ARHGEF10
1
ARHGEF10 [cytosol]
(R-HSA-8873917)
0.483
3
UniProt:Q9H9T3 ELP3
1
ELP3 [nucleoplasm]
(R-HSA-3318364)
0.483
2
UniProt:O75190 DNAJB6
2
DNAJB6 [cytosol]
(R-HSA-5252014)
DNAJB6 [nucleoplasm]
(R-HSA-5255425)
0.482
2
UniProt:O95801 TTC4
0.482
2
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