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DRG1 [cytosol]
Stable Identifier
R-HSA-9629563
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
Developmentally-regulated GTP-binding protein 1, NEDD3
Locations in the PathwayBrowser
Expand all
Metabolism of proteins (Homo sapiens)
Post-translational protein modification (Homo sapiens)
Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation (Homo sapiens)
Protein hydroxylation (Homo sapiens)
JMJD7 dimer hydroxlates a lysine residue of DRG1 (Homo sapiens)
DRG1:ZC3H15 [cytosol] (Homo sapiens)
DRG1 [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q9Y295 DRG1
Gene Names
DRG1, NEDD3
Chain
initiator methionine:, chain:2-367
Reference Genes
BioGPS Gene:4733 DRG1
COSMIC (genes):DRG1 DRG1
CTD Gene:4733 DRG1
dbSNP Gene:4733 DRG1
ENSEMBL:ENSG00000185721 DRG1
ENSEMBL_homo_sapiens_GENE:ENSG00000185721.13 DRG1
HGNC:3029 DRG1
KEGG Gene (Homo sapiens):4733 DRG1
Monarch:4733 DRG1
NCBI Gene:4733 DRG1
OMIM:603952 DRG1
UCSC:Q9Y295 DRG1
Reference Transcript
RefSeq:NM_004147.3 DRG1
Other Identifiers
11720181_a_at
11758825_at
11758826_x_at
11763609_a_at
16929203
202810_PM_at
202810_at
2542908
2542911
2542913
2542923
3942955
3942956
3942957
3942958
3942959
3942961
3942964
3942966
3942967
3942970
3942971
41606_at
4733
8072488
A_14_P100600
A_14_P134866
A_23_P68884
GE54709
GO:0000166
GO:0000278
GO:0002181
GO:0003824
GO:0003924
GO:0005515
GO:0005525
GO:0005634
GO:0005654
GO:0005737
GO:0005829
GO:0007010
GO:0007059
GO:0008017
GO:0008092
GO:0016020
GO:0016604
GO:0016787
GO:0030955
GO:0031116
GO:0042802
GO:0043226
GO:0046872
GO:0065003
GO:0140014
GO:1901673
HMNXSV003010999
ILMN_1658259
PH_hs_0029107
TC22001422.hg
g4758795_3p_at
Participates
as a component of
DRG1:ZC3H15 [cytosol] (Homo sapiens)
Other forms of this molecule
3OHK22-DRG1 [cytosol]
Inferred To
drg1 [cytosol]
(Danio rerio)
drg1 [cytosol]
(Xenopus tropicalis)
DRG1 [cytosol]
(Bos taurus)
DRG1 [cytosol]
(Caenorhabditis elegans)
DRG1 [cytosol]
(Canis familiaris)
DRG1 [cytosol]
(Dictyostelium discoideum)
DRG1 [cytosol]
(Drosophila melanogaster)
DRG1 [cytosol]
(Gallus gallus)
DRG1 [cytosol]
(Mus musculus)
DRG1 [cytosol]
(Saccharomyces cerevisiae)
DRG1 [cytosol]
(Schizosaccharomyces pombe)
DRG1 [cytosol]
(Sus scrofa)
Drg1 [cytosol]
(Rattus norvegicus)
Cross References
RefSeq
NP_004138.1
OpenTargets
ENSG00000185721
GeneCards
Q9Y295
HPA
ENSG00000185721-DRG1
Ensembl
ENSP00000329715
,
ENSG00000185721
,
ENST00000331457
PRO
Q9Y295
Pharos - Targets
Q9Y295
HMDB Protein
HMDBP08361
PDB
2EKI
Interactors (2)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P13569 CFTR
17
PolyUb-CFTR [clathrin-coated endocytic vesicle membrane]
(R-HSA-8869104)
PolyUb-CFTR [plasma membrane]
(R-HSA-8867595)
CFTR [lysosomal membrane]
(R-HSA-5627279)
CFTR [Golgi-associated vesicle membrane]
(R-HSA-5627079)
CFTR [endosome membrane]
(R-HSA-6782965)
PolyUb-CFTR [endosome membrane]
(R-HSA-6782976)
CFTR F508del [endoplasmic reticulum membrane]
(R-HSA-8866834)
ub-CFTR F508del [cytosol]
(R-HSA-8866838)
ub-CFTR F508del [endoplasmic reticulum membrane]
(R-HSA-8866842)
CFTR G542* [plasma membrane]
(R-HSA-5678986)
CFTR G551D [plasma membrane]
(R-HSA-5678977)
CFTR W1282* [plasma membrane]
(R-HSA-5678976)
CFTR F508del [plasma membrane]
(R-HSA-5678978)
CFTR N1303K [plasma membrane]
(R-HSA-5678983)
CFTR [plasma membrane]
(R-HSA-383188)
CFTR [endoplasmic reticulum membrane]
(R-HSA-8866837)
misfolded CFTR [endoplasmic reticulum membrane]
(R-HSA-8868730)
0.64
9
UniProt:P10636-8 MAPT
3
p-S199,S202,S262,S396,S404,S409,T181,T231-MAPT-8 [cytosol]
(R-HSA-9836400)
p-S262,S356,S396-MAPT-8 [cytosol]
(R-HSA-9619521)
MAPT-8 [cytosol]
(R-HSA-9619519)
0.527
4
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