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RPL27A [nucleoplasm]
Stable Identifier
R-HSA-9630984
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
60S ribosomal protein L27a, RL27A_HUMAN
Locations in the PathwayBrowser
Expand all
Metabolism of proteins (Homo sapiens)
Post-translational protein modification (Homo sapiens)
Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation (Homo sapiens)
Protein hydroxylation (Homo sapiens)
RIOX2Fe2+ hydroxylates a histidine residue of RPL27A (Homo sapiens)
RPL27A [nucleoplasm] (Homo sapiens)
External Reference Information
External Reference
UniProt:P46776 RPL27A
Gene Names
RPL27A
Chain
chain:1-148
Reference Genes
BioGPS Gene:6157 RPL27A
COSMIC (genes):RPL27A RPL27A
CTD Gene:6157 RPL27A
dbSNP Gene:6157 RPL27A
ENSEMBL:ENSG00000166441 RPL27A
ENSEMBL_homo_sapiens_GENE:ENSG00000166441.13 RPL27A
HGNC:10329 RPL27A
KEGG Gene (Homo sapiens):6157 RPL27A
Monarch:6157 RPL27A
NCBI Gene:6157 RPL27A
OMIM:603637 RPL27A
UCSC:P46776 RPL27A
Reference Transcript
RefSeq:NM_000990.4 RPL27A
Other Identifiers
11736810_at
16721715
203034_3p_s_at
203034_PM_s_at
203034_s_at
223707_PM_at
223707_at
2862831
2980367
2980370
2980371
32436_at
3319589
3319593
3319598
3319603
3319604
3319610
3319611
3319612
3319614
3319615
3319616
3319617
3319618
3319619
3319620
3319626
6157
77583_at
7938286
7938295
81234_at
8180404
83719_at
A_14_P114318
A_23_P203577
A_23_P416305
GE84889
GO:0002181
GO:0003723
GO:0003735
GO:0005198
GO:0005515
GO:0005634
GO:0005654
GO:0005737
GO:0005783
GO:0005829
GO:0005840
GO:0006412
GO:0015934
GO:0016020
GO:0022625
GO:0022626
GO:0043226
GO:0045202
GO:1990904
HMNXSV003013118
HMNXSV003043799
ILMN_1713086
PH_hs_0037283
U14968_at
g13279118_3p_at
g4506624_3p_a_at
g4506624_3p_x_at
Participates
as an input of
RIOX2Fe2+ hydroxylates a histidine residue of RPL27A (Homo sapiens)
Other forms of this molecule
3OHH39-RPL27A [nucleoplasm]
RPL27A [cytosol]
Inferred To
Rpl27al3 [nucleoplasm]
(Rattus norvegicus)
LOC106559080 [nucleoplasm]
(Canis familiaris)
RpL27A [nucleoplasm]
(Drosophila melanogaster)
rpl2802 [nucleoplasm]
(Schizosaccharomyces pombe)
RPL27A [nucleoplasm]
(Bos taurus)
RPL27A [nucleoplasm]
(Caenorhabditis elegans)
RPL27A [nucleoplasm]
(Canis familiaris)
RPL27A [nucleoplasm]
(Gallus gallus)
RPL27A [nucleoplasm]
(Plasmodium falciparum)
RPL27A [nucleoplasm]
(Sus scrofa)
rpl27a [nucleoplasm]
(Dictyostelium discoideum)
Homologues of RPL27A [nucleoplasm]
(Canis familiaris)
Homologues of RPL27A [nucleoplasm]
(Rattus norvegicus)
Homologues of RPL27A [nucleoplasm]
(Schizosaccharomyces pombe)
Rpl27a [nucleoplasm]
(Mus musculus)
Rpl27a [nucleoplasm]
(Rattus norvegicus)
rpl2801 [nucleoplasm]
(Schizosaccharomyces pombe)
RPL28 [nucleoplasm]
(Saccharomyces cerevisiae)
Cross References
RefSeq
NP_000981.1
OpenTargets
ENSG00000166441
GeneCards
P46776
HPA
ENSG00000166441-RPL27A
Ensembl
ENSP00000346015
,
ENSG00000166441
,
ENST00000314138
PRO
P46776
Pharos - Targets
P46776
PDB
8G61
,
8INF
,
8FKQ
,
8FKX
,
8FLF
,
4BXF
,
6OM0
,
8FKP
,
8JDJ
,
8FL9
,
6Y0G
,
7XNY
,
6QZP
,
8FKY
,
6OM7
,
8OJ5
,
8FLA
,
8G5Y
,
8FLB
,
8FKZ
,
8IDT
,
6OLE
,
7F5S
,
8FL2
,
8OJ0
,
6IP5
,
8IE3
,
8G5Z
,
5AJ0
,
8JDL
,
8INK
,
8FL6
,
6LSS
,
4UG0
,
6IP8
,
8IR1
,
6Y6X
,
8FLE
,
5LKS
,
8G6J
,
8IFE
,
8FL7
,
8GLP
,
8IPX
,
8A3D
,
6XA1
,
8IR3
,
6OLZ
,
4V6X
,
6ZME
,
8OHD
,
8IPY
,
8FKS
,
6Y2L
,
7BHP
,
8FKR
,
8JDK
,
6LU8
,
6ZMI
,
6ZMO
,
8FL3
,
8IPD
,
6OLF
,
8OJ8
,
8FLC
,
6Y57
,
6OLG
,
8FKU
,
6LQM
,
8FKT
,
7QVP
,
8IDY
,
6Z6L
,
8IFD
,
6LSR
,
8FL4
,
6IP6
,
8JDM
,
8QFD
,
8Y0X
,
8G60
,
8INE
,
8Y0W
,
6Z6M
,
7OW7
,
8FLD
,
5T2C
,
8FKW
,
6Z6N
,
6OLI
,
8FKV
,
6W6L
,
6ZM7
Interactors (13)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P0DTC9 N
13
SUMO1-K62-ADPr-p-11S,2T-metR95,177-N [plasma membrane]
(R-COV-9729325)
SUMO1-K62-ADPr-p-11S,2T-metR95,177-N [nucleolus]
(R-COV-9729339)
N [plasma membrane]
(R-COV-9694356)
SUMO1-K62,ADPr-,p-11S,2T,met-R95,177,Ac-K375-N [cytosol]
(R-COV-9756489)
N [cytosol]
(R-COV-9694300)
p-S188,206-N [cytosol]
(R-COV-9729324)
p-8S-N [cytosol]
(R-COV-9729335)
p-8S,2T-N [cytosol]
(R-COV-9729277)
p-11S,2T-N [cytosol]
(R-COV-9729264)
p-11S,2T-metR95,177-N [cytosol]
(R-COV-9729308)
ADPr-p-11S,2T-metR95,177-N [cytosol]
(R-COV-9729275)
SUMO1-K62-ADPr-p-11S,2T-metR95,177-N [endoplasmic reticulum-Golgi intermediate compartment membrane]
(R-COV-9729341)
SUMO1-K62-ADPr-p-11S,2T-metR95,177-N [cytosol]
(R-COV-9729340)
0.643
3
UniProt:P63244 RACK1
1
GNB2L1 [cytosol]
(R-HSA-5626956)
0.638
3
UniProt:Q9NR30 DDX21
1
DDX21 [nucleoplasm]
(R-HSA-5250652)
0.615
3
UniProt:Q86VP6 CAND1
5
CAND1 [cytosol]
(R-HSA-5691146)
CAND1 [ficolin-1-rich granule lumen]
(R-HSA-6801399)
CAND1 [extracellular region]
(R-HSA-6806498)
CAND1 [secretory granule lumen]
(R-HSA-6801390)
CAND1 [nucleoplasm]
(R-HSA-8955089)
0.564
2
UniProt:Q99848 EBNA1BP2
1
EBNA1BP2 [nucleoplasm]
(R-HSA-8869325)
0.527
2
UniProt:P13693 TCTP
0.527
2
UniProt:P26196 DDX6
1
DDX6 [cytosol]
(R-HSA-430032)
0.527
2
UniProt:P10636-8 MAPT
3
p-S199,S202,S262,S396,S404,S409,T181,T231-MAPT-8 [cytosol]
(R-HSA-9836400)
p-S262,S356,S396-MAPT-8 [cytosol]
(R-HSA-9619521)
MAPT-8 [cytosol]
(R-HSA-9619519)
0.527
5
UniProt:P19320 VCAM1
1
VCAM1 [plasma membrane]
(R-HSA-197834)
0.527
4
UniProt:P62913 RPL11
1
RPL11 [cytosol]
(R-HSA-72406)
0.527
2
UniProt:P13984 GTF2F2
1
GTF2F2 [nucleoplasm]
(R-HSA-65567)
0.524
2
UniProt:P13569 CFTR
17
PolyUb-CFTR [clathrin-coated endocytic vesicle membrane]
(R-HSA-8869104)
PolyUb-CFTR [plasma membrane]
(R-HSA-8867595)
CFTR [lysosomal membrane]
(R-HSA-5627279)
CFTR [Golgi-associated vesicle membrane]
(R-HSA-5627079)
CFTR [endosome membrane]
(R-HSA-6782965)
PolyUb-CFTR [endosome membrane]
(R-HSA-6782976)
CFTR F508del [endoplasmic reticulum membrane]
(R-HSA-8866834)
ub-CFTR F508del [cytosol]
(R-HSA-8866838)
ub-CFTR F508del [endoplasmic reticulum membrane]
(R-HSA-8866842)
CFTR G542* [plasma membrane]
(R-HSA-5678986)
CFTR G551D [plasma membrane]
(R-HSA-5678977)
CFTR W1282* [plasma membrane]
(R-HSA-5678976)
CFTR F508del [plasma membrane]
(R-HSA-5678978)
CFTR N1303K [plasma membrane]
(R-HSA-5678983)
CFTR [plasma membrane]
(R-HSA-383188)
CFTR [endoplasmic reticulum membrane]
(R-HSA-8866837)
misfolded CFTR [endoplasmic reticulum membrane]
(R-HSA-8868730)
0.483
12
UniProt:P03372 ESR1
10
p-S118-ESR1 [nucleoplasm]
(R-HSA-9024210)
monoSUMO1-5K-ESR1 [nucleoplasm]
(R-HSA-4090302)
p-S167-ESR1 [nucleoplasm]
(R-HSA-9841867)
p-S167-ESR1 [cytosol]
(R-HSA-9841254)
Me260-ESR1 [cytosol]
(R-HSA-9632177)
PalmS-ESR1 [cytosol]
(R-HSA-9020974)
Me260-PalmS-ESR1 [plasma membrane]
(R-HSA-9637788)
PalmS-ESR1 [plasma membrane]
(R-HSA-9021057)
ESR1 [nucleoplasm]
(R-HSA-446168)
ESR1 [cytosol]
(R-HSA-9020968)
0.462
2
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