Reactome | ASPH [endoplasmic reticulum lumen]

ASPH [endoplasmic reticulum lumen]

Stable Identifier

R-HSA-9631383

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

endoplasmic reticulum lumen

Synonyms

Aspartyl/asparaginyl beta-hydroxylase, ASPH_HUMAN, junctin

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q12797 ASPH

Gene Names

ASPH, BAH

Chain

chain:1-758

Reference Genes

BioGPS Gene:444 ASPH

COSMIC (genes):ASPH ASPH

CTD Gene:444 ASPH

dbSNP Gene:444 ASPH

ENSEMBL:ENSG00000198363 ASPH

HGNC:757 ASPH

KEGG:hsa:444 ASPH

Monarch:444 ASPH

NCBI Gene:444 ASPH

OMIM:600582 ASPH

UCSC:Q12797 ASPH

Reference Transcript

Participates

as a component of

ASPH:Fe2+ [endoplasmic reticulum lumen] (Homo sapiens)

Other forms of this molecule

ASPH [endoplasmic reticulum membrane]

Cross References

OpenTargets

ENSG00000198363

ENSEMBL

ENST00000517903, ENSP00000368767, ENSP00000430245, ENSP00000394013, ENSP00000429954, ENSP00000368762, ENST00000522835, ENST00000389204, ENSP00000373856, ENST00000379449, ENST00000522603, ENSP00000348841, ENST00000541428, ENST00000445642, ENSP00000437864, ENST00000356457, ENST00000518068, ENSP00000436188, ENSP00000429160, ENST00000379454, ENSG00000198363, ENSP00000429286, ENST00000517847

HPA

ENSG00000198363-ASPH

GeneCards

ASPH

PRO

Q12797

Pharos - Targets

Q12797

GlyGen

Q12797

Orphanet

ASPH

HMDB Protein

HMDBP01022

PDB

6YYU, 6Z6Q, 6Q9I, 6YYX, 6YYY, 5JZ6, 7YBA, 7BMJ, 7YBC, 6Q9F, 7YB9, 6YYV, 7E6J, 7YBB, 6Z6R, 6YYW, 7YB8, 6QA5, 5JZU, 6RK9, 5JTC, 5JZA, 5JQY, 5APA, 7BMI, 5JZ8

Interactors (11)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q9H4I9 SMDT1	3	SMDT1 [mitochondrial inner membrane] (R-HSA-8949227) proSMDT1 [mitochondrial inner membrane] (R-HSA-8949655) SMDT1 transit peptide [mitochondrial matrix] (R-HSA-8949642)	0.527	2
UniProt:Q12846 STX4	4	STX4 [plasma membrane] (R-HSA-181519) STX4 [phagocytic vesicle membrane] (R-HSA-2029044) STX4 [cytosol] (R-HSA-114505) p-STX4 [cytosol] (R-HSA-114681)	0.527	3
UniProt:Q9NWR8 MCUB	1	MCUB [mitochondrial inner membrane] (R-HSA-8949153)	0.527	3
UniProt:Q8NC56 LEMD2	1	LEMD2 [nuclear envelope] (R-HSA-3067329)	0.527	3
UniProt:P06276 BCHE	2	BCHE [plasma membrane] (R-HSA-3640835) BCHE [extracellular region] (R-HSA-434469)	0.527	2
UniProt:Q99435 NELL2	1	NELL2 [extracellular region] (R-HSA-9010198)	0.527	2
UniProt:O00186 STXBP3	4	p-Y521-STXBP3 [plasma membrane] (R-HSA-2263472) STXBP3 [plasma membrane] (R-HSA-2263473) p-STXBP3 [cytosol] (R-HSA-114680) STXBP3 [cytosol] (R-HSA-114682)	0.527	3
UniProt:Q12981 BNIP1	1	BNIP1 [endoplasmic reticulum membrane] (R-HSA-6810950)	0.527	2
UniProt:Q9BQ95 ECSIT	2	ECSIT [cytosol] (R-HSA-168064) ECSIT [mitochondrial inner membrane] (R-HSA-5689047)	0.527	3
UniProt:Q8NE86 MCU	1	MCU [mitochondrial inner membrane] (R-HSA-8949184)	0.527	3
UniProt:P0DTC8 8	2	8 [extracellular region] (R-COV-9755410) 8 [endoplasmic reticulum lumen] (R-COV-9727283)	0.482	2

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