Reactome | NUP54 [cytosol]

NUP54 [cytosol]

Stable Identifier

R-HSA-9634221

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

Nup54

Locations in the PathwayBrowser

Expand all

Cell Cycle (Homo sapiens)

- Cell Cycle, Mitotic (Homo sapiens)
  - M Phase (Homo sapiens)
    - Mitotic Metaphase and Anaphase (Homo sapiens)
      - Mitotic Anaphase (Homo sapiens)
        
        Nuclear Envelope (NE) Reassembly (Homo sapiens)
        
        Postmitotic nuclear pore complex (NPC) reformation (Homo sapiens)
        
        NUP93 recruits the Nup62 complex (Homo sapiens)
        
        Nup62 Complex [cytosol] (Homo sapiens)
        
        NUP54 [cytosol] (Homo sapiens)
        
        Nup62 complex:Nup93 complex:NUP188:NDC1:POM121:AHCTF1:Chromatin [nuclear envelope] (Homo sapiens)
        
        Nup62 Complex [cytosol] (Homo sapiens)
        
        NUP54 [cytosol] (Homo sapiens)

External Reference Information

External Reference

UniProt:Q7Z3B4 NUP54

Gene Names

NUP54

Chain

chain:1-507

Reference Genes

BioGPS Gene:53371 NUP54

COSMIC (genes):NUP54 NUP54

CTD Gene:53371 NUP54

dbSNP Gene:53371 NUP54

ENSEMBL:ENSG00000138750 NUP54

HGNC:17359 NUP54

KEGG:hsa:53371 NUP54

Monarch:53371 NUP54

NCBI Gene:53371 NUP54

OMIM:607607 NUP54

UCSC:Q7Z3B4 NUP54

Reference Transcript

Other Identifiers

11743662_a_at

11743663_x_at

11752498_a_at

11756835_a_at

16977066

218256_PM_s_at

218256_s_at

2773996

2773998

2773999

2774000

2774001

2774002

2774003

2774004

2774005

2774006

2774011

2774012

2774013

2774014

2774015

2774016

2774017

2774018

2774019

2774021

2774022

2774023

2774024

2774025

2774027

2774029

2774030

2774031

2774032

2774033

2774037

2774040

48691_at

53371

8101143

86635_at

89198_at

A_23_P92320

GE62585

GE878333

GO:0005198

GO:0005515

GO:0005634

GO:0005635

GO:0005643

GO:0006605

GO:0006607

GO:0006886

GO:0006913

GO:0006999

GO:0015031

GO:0016020

GO:0017056

GO:0031965

GO:0032991

GO:0036228

GO:0042306

GO:0042802

GO:0043226

GO:0044613

GO:0044877

GO:0051028

HMNXSV003016772

HMNXSV003032036

Hs.202386.0.A1_3p_at

ILMN_1771835

ILMN_2061405

PH_hs_0000960

TC04001307.hg

g8393857_3p_a_at

Participates

as a component of

Nup62 Complex [cytosol] (Homo sapiens)

Other forms of this molecule

NUP54 [nuclear envelope]

Cross References

RefSeq

NP_059122.2, NP_001265532.1

ENSEMBL

ENST00000264883, ENSP00000264883, ENSP00000421304, ENST00000514987, ENSG00000138750

OpenTargets

ENSG00000138750

GeneCards

NUP54

HPA

ENSG00000138750-NUP54

PRO

Q7Z3B4

Pharos - Targets

Q7Z3B4

GlyGen

Q7Z3B4

PDB

7PER, 7N8R, 5IJN, 5IJO, 7R5K, 4JNV, 4JO7, 4JNU, 4JO9, 7R5J

Interactors (8)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:O14964 HGS	2	HGS [cytosol] (R-HSA-182954) HGS [phagocytic vesicle lumen] (R-HSA-9635660)	0.781	7
UniProt:Q9NV70 EXOC1	2	EXOC1 [plasma membrane] (R-HSA-2872284) EXOC1 [cytosol] (R-HSA-5623375)	0.743	5
UniProt:Q9BXU0 TEX12	1	TEX12 [nucleoplasm] (R-HSA-912441)	0.556	3
UniProt:P55212 CASP6	5	CASP6(194-293) [cytosol] (R-HSA-266128) CASP6(24-179) [cytosol] (R-HSA-350313) CASP6(24-179) [nucleoplasm] (R-HSA-352247) CASP6(194-293) [nucleoplasm] (R-HSA-352246) CASP6 (1-293) [cytosol] (R-HSA-6798132)	0.556	3
UniProt:Q9Y6A5 TACC3	1	TACC3 [cytosol] (R-HSA-2160956)	0.556	3
UniProt:Q8IYI6 EXOC8	2	EXOC8 [plasma membrane] (R-HSA-264948) EXOC8 [cytosol] (R-HSA-5623388)	0.556	3
UniProt:Q8IY31 IFT20	3	IFT20 [cilium] (R-HSA-5617624) IFT20 [Golgi membrane] (R-HSA-5617625) IFT20 [ciliary tip] (R-HSA-5625355)	0.556	3
UniProt:P06307 CCK	1	CCK [extracellular region] (R-HSA-388539)	0.556	3