Reactome | NUP54 [cytosol]

NUP54 [cytosol]

Stable Identifier

R-HSA-9634221

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

Nup54

Locations in the PathwayBrowser

Expand all

Cell Cycle (Homo sapiens)

- Cell Cycle, Mitotic (Homo sapiens)
  - M Phase (Homo sapiens)
    - Mitotic Metaphase and Anaphase (Homo sapiens)
      - Mitotic Anaphase (Homo sapiens)
        
        Nuclear Envelope (NE) Reassembly (Homo sapiens)
        
        Postmitotic nuclear pore complex (NPC) reformation (Homo sapiens)
        
        NUP93 recruits the Nup62 complex (Homo sapiens)
        
        Nup62 Complex [cytosol] (Homo sapiens)
        
        NUP54 [cytosol] (Homo sapiens)
        
        Nup62 complex:Nup93 complex:NUP188:NDC1:POM121:AHCTF1:Chromatin [nuclear envelope] (Homo sapiens)
        
        Nup62 Complex [cytosol] (Homo sapiens)
        
        NUP54 [cytosol] (Homo sapiens)

External Reference Information

External Reference

UniProt:Q7Z3B4 NUP54

Gene Names

NUP54

Chain

chain:1-507

Reference Genes

BioGPS Gene:53371 NUP54

COSMIC (genes):NUP54 NUP54

CTD Gene:53371 NUP54

dbSNP Gene:53371 NUP54

ENSEMBL:ENSG00000138750 NUP54

ENSEMBL_homo_sapiens_GENE:ENSG00000138750.16 NUP54

HGNC:17359 NUP54

KEGG Gene (Homo sapiens):53371 NUP54

Monarch:53371 NUP54

NCBI Gene:53371 NUP54

OMIM:607607 NUP54

UCSC:Q7Z3B4 NUP54

Reference Transcript

Other Identifiers

11743662_a_at

11743663_x_at

11752498_a_at

11756835_a_at

218256_PM_s_at

218256_s_at

2773998

2773999

2774000

2774001

2774002

2774003

2774005

2774012

2774013

2774016

2774019

2774021

2774023

2774024

2774025

2774032

2774033

48691_at

53371

8101143

89198_at

A_23_P92320

GE62585

GO:0005198

GO:0005515

GO:0005634

GO:0005635

GO:0005643

GO:0006605

GO:0006607

GO:0006886

GO:0006913

GO:0006999

GO:0015031

GO:0016020

GO:0017056

GO:0031965

GO:0032991

GO:0036228

GO:0042306

GO:0042802

GO:0043226

GO:0044613

GO:0044877

GO:0051028

HMNXSV003016772

HMNXSV003032036

ILMN_1771835

ILMN_2061405

PH_hs_0000960

g8393857_3p_a_at

Participates

as a component of

Nup62 Complex [cytosol] (Homo sapiens)

Other forms of this molecule

NUP54 [nuclear envelope]

Cross References

RefSeq

NP_059122.2, NP_001265532.1

OpenTargets

ENSG00000138750

GeneCards

Q7Z3B4

HPA

ENSG00000138750-NUP54

Ensembl

ENSG00000138750, ENST00000264883, ENST00000514987, ENSP00000421304, ENSP00000264883

PRO

Q7Z3B4

Pharos - Targets

Q7Z3B4

PDB

7PER, 5IJN, 5IJO, 4JO7, 7N8R, 7R5J, 4JNU, 4JNV, 7R5K, 4JO9

Interactors (8)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:O14964 HGS	2	HGS [cytosol] (R-HSA-182954) HGS [phagocytic vesicle lumen] (R-HSA-9635660)	0.781	7
UniProt:Q9NV70 EXOC1	2	EXOC1 [plasma membrane] (R-HSA-2872284) EXOC1 [cytosol] (R-HSA-5623375)	0.666	4
UniProt:Q9Y6A5 TACC3	1	TACC3 [cytosol] (R-HSA-2160956)	0.556	3
UniProt:P06307 CCK	1	CCK [extracellular region] (R-HSA-388539)	0.556	3
UniProt:P55212 CASP6	5	CASP6 (1-293) [cytosol] (R-HSA-6798132) CASP6(194-293) [nucleoplasm] (R-HSA-352246) CASP6(24-179) [nucleoplasm] (R-HSA-352247) CASP6(24-179) [cytosol] (R-HSA-350313) CASP6(194-293) [cytosol] (R-HSA-266128)	0.556	3
UniProt:Q9BXU0 TEX12	1	TEX12 [nucleoplasm] (R-HSA-912441)	0.556	3
UniProt:Q8IYI6 EXOC8	2	EXOC8 [plasma membrane] (R-HSA-264948) EXOC8 [cytosol] (R-HSA-5623388)	0.556	3
UniProt:Q8IY31 IFT20	3	IFT20 [cilium] (R-HSA-5617624) IFT20 [Golgi membrane] (R-HSA-5617625) IFT20 [ciliary tip] (R-HSA-5625355)	0.556	3