CDK5R1 gene expression is stimulated by NPAS4

Stable Identifier
R-HSA-9634934
Type
Reaction [omitted]
Species
Homo sapiens
Compartment
nucleoplasm, plasma membrane
ReviewStatus
5/5
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CDK5R1 gene expression is stimulated by NPAS4
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Based on mouse studies, NPAS4 directly stimulates expression of the CDK5R1 gene, encoding p35, a neuronal activator of CDK5 (Yun et al. 2013). In rat primary neurons, Cdk5r1 gene transcription is significantly upregulated upon Npas4 activation (Brigidi et al. 2019).
Participants
Input
Output
Participates
as an event of
This event is regulated
Positively by
Regulator
(NPAS4:ARNTL,NPAS4:ARNT,NPAS4:ARNT2):CDK5R1 gene [nucleoplasm] (Homo sapiens)
Active Unit
(NPAS4:ARNTL,NPAS4:ARNT,NPAS4:ARNT2) [nucleoplasm]
Inferred From
Cdk5r1 gene expression is stimulated by Npas4 (Mus musculus)
Authored
Orlic-Milacic, M  (2022-04-08)
Reviewed
Lin, Y  (2022-07-29)
Created
Orlic-Milacic, M  (2019-01-17)
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