PPE2:KPNA1:KPNB1 translocates to the nucleus

Stable Identifier
R-HSA-9636247
Type
Reaction [uncertain]
Species
Homo sapiens
Related Species
Mycobacterium tuberculosis
Compartment
cytosol, nucleoplasm
ReviewStatus
5/5
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PPE2:KPNA1:KPNB1 translocates to the nucleus
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PPE family protein PPE2 is translocated to the phagocyte's nucleus via the importin α/β (KPNA1:KPNB1) pathway (Bhat 2017).
Literature References
PubMed ID Title Journal Year
28071726 The PPE2 protein of Mycobacterium tuberculosis translocates to host nucleus and inhibits nitric oxide production

Ghosh, S, Mukhopadhyay, S, Kotturu, SK, Bhat, KH, Srivastava, S

Sci Rep 2017
Participants
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Output
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as an event of
Disease
Name Identifier Synonyms
tuberculosis DOID:399 tuberculous abscess, Tuberculoma (finding), tuberculoma
Authored
Stephan, R  (2019-02-06)
Reviewed
Wilkinson, RJ  (2019-10-23)
Deffur, A  (2019-10-23)
Created
Koile, I  (2019-02-12)
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