Reactome | p-Y133-VPS33B [cytosol]

p-Y133-VPS33B [cytosol]

Stable Identifier

R-HSA-9636380

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

p-Y133-Vacuolar protein sorting-associated protein 33B, p-Y133-VP33B_HUMAN

Locations in the PathwayBrowser

Expand all

Disease (Homo sapiens)

- Infectious disease (Homo sapiens)
  - Bacterial Infection Pathways (Homo sapiens)
    - Infection with Mycobacterium tuberculosis (Homo sapiens)
      - Response of Mtb to phagocytosis (Homo sapiens)
        
        Suppression of phagosomal maturation (Homo sapiens)
        
        Prevention of phagosomal-lysosomal fusion (Homo sapiens)
        
        PtpA:Ub dephosphorylates p-Y133-VPS33B (Homo sapiens)
        
        p-Y133-VPS33B [cytosol] (Homo sapiens)

External Reference Information

External Reference

UniProt:Q9H267 VPS33B

Gene Names

VPS33B

Chain

initiator methionine:, chain:2-617

Reference Genes

BioGPS Gene:26276 VPS33B

COSMIC (genes):VPS33B VPS33B

CTD Gene:26276 VPS33B

dbSNP Gene:26276 VPS33B

ENSEMBL:ENSG00000184056 VPS33B

ENSEMBL_homo_sapiens_GENE:ENSG00000184056.15 VPS33B

HGNC:12712 VPS33B

KEGG Gene (Homo sapiens):26276 VPS33B

Monarch:26276 VPS33B

NCBI Gene:26276 VPS33B

OMIM:608552 VPS33B

UCSC:Q9H267 VPS33B

Reference Transcript

Other Identifiers

11718352_a_at

11748431_a_at

16813372

218415_PM_at

218415_at

26276

3639071

3639072

3639073

3639075

3639076

3639077

3639079

3639080

3639081

3639082

3639083

3639084

3639085

3639086

3639087

3639088

3639089

3639090

3639091

3639092

3639094

3639096

3639097

3639098

3639099

3639102

3639103

44111_PM_at

44111_at

4870633C_3p_at

7991427

A_23_P48964

GE61201

GO:0005515

GO:0005737

GO:0005764

GO:0005765

GO:0005768

GO:0005769

GO:0005770

GO:0005773

GO:0005794

GO:0005829

GO:0006886

GO:0007032

GO:0007040

GO:0007155

GO:0010008

GO:0015031

GO:0016020

GO:0016192

GO:0017185

GO:0030136

GO:0030154

GO:0030198

GO:0030199

GO:0030897

GO:0031091

GO:0031410

GO:0031901

GO:0031902

GO:0032400

GO:0032418

GO:0032963

GO:0033263

GO:0035855

GO:0036211

GO:0042060

GO:0043226

GO:0043589

GO:0044877

GO:0046907

GO:0048471

GO:0048856

GO:0055037

GO:0061024

GO:0061025

GO:0070889

GO:0090330

GO:0090385

GO:0099023

HMNXSV003013029

HMNXSV003057004

ILMN_1789243

PH_hs_0023820

TC15001860.hg

g9945311_3p_s_at

Participates

as an input of

PtpA:Ub dephosphorylates p-Y133-VPS33B (Homo sapiens)

Other forms of this molecule

VPS33B [cytosol]

VPS33B [endosome membrane]

Modified Residues

Name

O4'-phospho-L-tyrosine at 133

Coordinate

133

PsiMod Name

O4'-phospho-L-tyrosine [MOD:00048]

PsiMod Definition

A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.

Cross References

RefSeq

XP_005254944.1, XP_011519750.1, NP_001276078.1, NP_061138.3, NP_001276077.1

OpenTargets

ENSG00000184056

HPA

ENSG00000184056-VPS33B

GeneCards

Q9H267

Ensembl

ENST00000333371, ENSG00000184056, ENSP00000327650

PRO

Q9H267

Pharos - Targets

Q9H267

Interactors (4)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q9H9C1 SPE39			0.975	39
UniProt:Q15025 TNIP1	1	TNIP1 [cytosol] (R-HSA-5690853)	0.805	9
UniProt:Q6IA61 Q6IA61			0.556	3
UniProt:O60826 CCDC22	2	CCDC22 [nucleoplasm] (R-HSA-8955644) CCDC22 [cytosol] (R-HSA-8955640)	0.527	4