Suppression of autophagy

Stable Identifier
R-HSA-9636569
Type
Pathway
Species
Homo sapiens
Related Species
Mycobacterium tuberculosis
ReviewStatus
5/5
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Suppression of autophagy
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Autophagy, a distinct pathway of programmed cell death, is used by the phagocyte primarily to eradicate damaged cell organelles or unused proteins. As Mtb damages the phagosomal membrane it has to block autophagy processes to ensure maximum replication before exit from the cell (Jo 2013).
Literature References
PubMed ID Title Journal Year
23620156 Autophagy as an innate defense against mycobacteria

Jo, EK

Pathog Dis 2013
Participants
Events
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as an event of
Event Information
Go Biological Process
suppression by symbiont of host defense-related programmed cell death (0034054)
Disease
Name Identifier Synonyms
tuberculosis DOID:399 tuberculous abscess, Tuberculoma (finding), tuberculoma
Authored
Stephan, R  (2019-02-06)
Reviewed
Wilkinson, RJ  (2019-10-23)
Deffur, A  (2019-10-23)
Created
Pardo, AM  (2019-02-13)
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