PstS1 binds MRC1

Stable Identifier
R-HSA-9637605
Type
Reaction [binding]
Species
Homo sapiens
Related Species
Mycobacterium tuberculosis
Compartment
peptidoglycan-based cell wall, plasma membrane
ReviewStatus
5/5
Locations in the PathwayBrowser
Expand all
General
SVG | 
PNG
Low
Medium
High
 | PPTX  | SBGN
PstS1 binds MRC1
Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout
Human macrophage mannose receptor (MRC1) recognizes Mtb by binding to phosphate-binding protein PstS1 (PstS1), which contains two molecules of mannose (Esparza et al. 2015).
Literature References
PubMed ID Title Journal Year
25359607 PstS-1, the 38-kDa Mycobacterium tuberculosis glycoprotein, is an adhesin, which binds the macrophage mannose receptor and promotes phagocytosis

Zenteno, E, García, T, Esparza, M, Mancilla, R, Espinosa, P, Palomares, B

Scand. J. Immunol. 2015
Participants
Input
Output
Participates
as an event of
Disease
Name Identifier Synonyms
tuberculosis DOID:399 tuberculous abscess, Tuberculoma (finding), tuberculoma
Authored
Stephan, R  (2019-02-19)
Reviewed
Wilkinson, RJ  (2019-10-23)
Deffur, A  (2019-10-23)
Created
Pardo, AM  (2019-02-19)
Cite Us!