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MIA2 [endoplasmic reticulum membrane]
Stable Identifier
R-HSA-9637821
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
endoplasmic reticulum membrane
Synonyms
fullName evidence="21"Melanoma inhibitory activity protein 2, MIA2_HUMAN
Locations in the PathwayBrowser for interactor UniProt:Q86XR8 CEP57
Expand all
Metabolism of proteins (Homo sapiens)
Post-translational protein modification (Homo sapiens)
Asparagine N-linked glycosylation (Homo sapiens)
Transport to the Golgi and subsequent modification (Homo sapiens)
ER to Golgi Anterograde Transport (Homo sapiens)
Cargo concentration in the ER (Homo sapiens)
MIA2 binds PREB (Homo sapiens)
MIA2 [endoplasmic reticulum membrane] (Homo sapiens)
Vesicle-mediated transport (Homo sapiens)
Membrane Trafficking (Homo sapiens)
ER to Golgi Anterograde Transport (Homo sapiens)
Cargo concentration in the ER (Homo sapiens)
MIA2 binds PREB (Homo sapiens)
MIA2 [endoplasmic reticulum membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q96PC5 MIA2
Gene Names
MIA2, CTAGE5, MEA11, MEA6, MGEA11, MGEA6
Chain
signal peptide:1-19, chain:20-1412
Reference Genes
BioGPS Gene:4253 MIA2
COSMIC (genes):MIA2 MIA2
CTD Gene:4253 MIA2
dbSNP Gene:4253 MIA2
ENSEMBL:ENSG00000150527 CTAGE5
HGNC:18432 MIA2
KEGG:hsa:4253 MIA2
Monarch:4253 MIA2
NCBI Gene:4253 MIA2
OMIM:602132 MIA2
UCSC:Q96PC5 MIA2
Reference Transcript
RefSeq:XM_017021320.1 MIA2
RefSeq:NM_001247989.1 MIA2
RefSeq:NM_001247988.1 MIA2
RefSeq:XM_011536784.2 MIA2
RefSeq:XM_006720148.2 MIA2
RefSeq:NM_005930.3 MIA2
RefSeq:NM_203354.2 MIA2
RefSeq:NM_054024.3 MIA2
RefSeq:XM_011536785.2 MIA2
RefSeq:XM_017021325.1 MIA2
RefSeq:NM_001329214.1 MIA2
RefSeq:NM_203356.2 MIA2
RefSeq:NM_001247990.1 MIA2
Other Identifiers
11731056_a_at
11731874_x_at
11737965_at
11755659_x_at
11759858_at
1228_s_at
1553944_PM_at
1553944_at
16783662
204055_PM_s_at
204055_s_at
215930_PM_s_at
215930_s_at
221177_PM_at
221177_at
3533486
3533487
3533488
3533489
3533490
3533491
3533493
3533494
3533495
3533496
3533497
3533498
3533500
3533501
3533504
3533505
3533506
3533507
3533508
3533509
3533510
3533515
3533516
3533518
3533519
3533520
3533521
3533522
3533524
3533525
3533527
3533528
3533529
3533530
3533531
3533532
3533533
3533534
3533535
3533536
3533538
3533539
3533540
3533541
3533543
3533547
3533548
3533549
3533550
3533551
3533559
3533560
3533565
41615_at
4253
7974080
7974090
A_14_P109745
A_14_P113093
A_14_P116503
A_14_P120479
A_14_P139658
A_23_P117387
A_23_P128773
A_24_P333326
A_32_P121362
A_33_P3246017
GE83057
GO:0005515
GO:0005783
GO:0005789
GO:0006886
GO:0006888
GO:0008047
GO:0009306
GO:0016020
GO:0016192
GO:0032527
GO:0035459
GO:0038024
GO:0042953
GO:0043226
GO:0070971
GO:0070973
GO:0098772
HMNXSV003006673
HMNXSV003015815
HMNXSV003017094
Hs.117242.1.A1_3p_a_at
Hs2.350568.1.S1_3p_at
ILMN_1656743
ILMN_1662914
ILMN_1690880
ILMN_1754956
ILMN_2158665
ILMN_2314080
PH_hs_0014900
PH_hs_0028418
PH_hs_0041070
TC14002295.hg
TC14002296.hg
U73682_at
g13376567_3p_at
g5174560_3p_a_at
Participates
as an input of
MIA2 binds PREB (Homo sapiens)
as a component of
MIA2:MIA3 [endoplasmic reticulum membrane] (Homo sapiens)
MIA2:PREB [endoplasmic reticulum membrane] (Homo sapiens)
Inferred To
Mia2 [endoplasmic reticulum membrane]
(Mus musculus)
Mia2 [endoplasmic reticulum membrane]
(Rattus norvegicus)
Ghost homologue of MIA2 [endoplasmic reticulum membrane]
(Xenopus tropicalis)
MIA2 [endoplasmic reticulum membrane]
(Bos taurus)
MIA2 [endoplasmic reticulum membrane]
(Canis familiaris)
MIA2 [endoplasmic reticulum membrane]
(Gallus gallus)
MIA2 [endoplasmic reticulum membrane]
(Sus scrofa)
Tango1 [endoplasmic reticulum membrane]
(Drosophila melanogaster)
Cross References
OpenTargets
ENSG00000150527
ENSEMBL
ENST00000553352
,
ENSP00000379468
,
ENST00000341749
,
ENSP00000379462
,
ENST00000341502
,
ENST00000640607
,
ENST00000348007
,
ENST00000280083
,
ENST00000556148
,
ENST00000280082
,
ENST00000557038
,
ENSP00000343897
,
ENSP00000450449
,
ENSP00000450869
,
ENST00000396158
,
ENSP00000491014
,
ENSP00000452562
,
ENSP00000280083
,
ENST00000396165
,
ENSP00000339286
,
ENSP00000343912
,
ENSP00000280082
HPA
ENSG00000150527-MIA2
PRO
Q96PC5
Pharos - Targets
Q96PC5
GlyGen
Q96PC5
Interactors (26)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P25788 PSMA3
2
PSMA3 [cytosol]
(R-HSA-68728)
PSMA3 [nucleoplasm]
(R-HSA-174323)
0.556
3
UniProt:Q08117 TLE5
1
AES [nucleoplasm]
(R-HSA-4648963)
0.556
3
UniProt:Q86XR8 CEP57
1
CEP57 [cytosol]
(R-HSA-380271)
0.556
3
UniProt:Q6PF05-3 TTC23L
0.556
3
UniProt:Q9UJF2 RASAL2
1
RASAL2 [cytosol]
(R-HSA-5658224)
0.556
3
UniProt:Q96M61 MAGBI
0.556
3
UniProt:Q9Y6C2 EMILIN1
1
EMILIN1 [extracellular region]
(R-HSA-2161355)
0.556
3
UniProt:Q8TD31-3 CCHCR1
0.556
3
UniProt:O75177 SS18L1
1
SS18L1 [nucleoplasm]
(R-HSA-9727481)
0.556
3
UniProt:P18846 ATF1
2
ATF1 [nucleoplasm]
(R-HSA-199900)
p-S63-ATF1 [nucleoplasm]
(R-HSA-199897)
0.527
2
UniProt:Q9HC35 EML4
12
EML4 [cytosol]
(R-HSA-9647741)
p-S,T-EML4 [cytosol]
(R-HSA-9648096)
EML4(1-496)-ALK(1058-1620) fusion [cytosol]
(R-HSA-9699812)
EML4(1-223)-ALK(1059-1620) fusion [cytosol]
(R-HSA-9699862)
EML4(1-223)insKMSTREKNSQV-ALK(1059-1620) fusion [cytosol]
(R-HSA-9699813)
EML4(1-780)-p-7Y-ALK(1058-1620) fusion [cytosol]
(R-HSA-9716113)
EML4(1-569)-p-7Y-ALK(1078-1620) fusion [cytosol]
(R-HSA-9716116)
EML4(1-223)-p-7Y-ALK(1059-1620) fusion [cytosol]
(R-HSA-9699903)
EML4(1-223)insKMSTREKNSQV-p-7Y-ALK(1059-1620) fusion [cytosol]
(R-HSA-9699885)
EML4(1-486)-p-7Y-ALK(1058-1620) fusion [cytosol]
(R-HSA-9699918)
EML4(1-569)-ALK(1078-1620) fusion [cytosol]
(R-HSA-9716112)
EML4(1-780)-ALK(1058-1620) fusion [cytosol]
(R-HSA-9716119)
0.527
2
UniProt:Q16625 OCLN
4
OCLN [plasma membrane]
(R-HSA-351846)
OCLN(321-522) [plasma membrane]
(R-HSA-351873)
OCLN(1-320) [plasma membrane]
(R-HSA-351854)
OCLN [cell junction]
(R-HSA-2160944)
0.527
2
UniProt:Q9UBI1 COMMD3
4
COMMD3 [nucleoplasm]
(R-HSA-8955108)
COMMD3 [cytosol]
(R-HSA-8955113)
COMMD3 [extracellular region]
(R-HSA-6806501)
COMMD3 [ficolin-1-rich granule lumen]
(R-HSA-6801405)
0.527
2
UniProt:Q4KMQ2 ANO6
3
ANO6 [tertiary granule membrane]
(R-HSA-6800903)
ANO6 [plasma membrane]
(R-HSA-2684941)
ANO6 [specific granule membrane]
(R-HSA-6799509)
0.527
2
UniProt:P14735 IDE
5
IDE [mitochondrial outer membrane]
(R-HSA-5696861)
PolyUb-IDE [mitochondrial outer membrane]
(R-HSA-6783095)
IDE [peroxisomal matrix]
(R-HSA-9033157)
IDE [cytosol]
(R-HSA-9033133)
IDE [endosome lumen]
(R-HSA-9794504)
0.527
2
UniProt:Q9BUZ4 TRAF4
0.527
2
UniProt:Q99666 RGPD5
0.527
2
UniProt:Q92633 LPAR1
1
LPAR1 [plasma membrane]
(R-HSA-419354)
0.527
2
UniProt:Q15390 MTFR1
0.527
2
UniProt:O60826 CCDC22
2
CCDC22 [nucleoplasm]
(R-HSA-8955644)
CCDC22 [cytosol]
(R-HSA-8955640)
0.527
2
UniProt:O14715 RGPD8
0.527
2
UniProt:Q86X83 COMMD2
2
COMMD2 [nucleoplasm]
(R-HSA-8955099)
COMMD2 [cytosol]
(R-HSA-8955112)
0.527
2
UniProt:A6NKT7 RGPD3
0.527
2
UniProt:Q96RT6 CTGE2
0.527
2
UniProt:Q9NRK6 ABCB10
1
ABCB10 [mitochondrial inner membrane]
(R-HSA-1369015)
0.527
2
UniProt:Q53EZ4 CEP55
0.527
2
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