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GSDMD pore complex [plasma membrane]
Stable Identifier
R-HSA-9647630
Type
Complex
Species
Homo sapiens
Compartment
plasma membrane
Locations in the PathwayBrowser
Expand all
Disease (Homo sapiens)
Infectious disease (Homo sapiens)
Parasitic Infection Pathways (Homo sapiens)
Leishmania infection (Homo sapiens)
Cell recruitment (pro-inflammatory response) (Homo sapiens)
Purinergic signaling in leishmaniasis infection (Homo sapiens)
Interleukin-1 family are secreted (Homo sapiens)
GSDMD pore complex [plasma membrane] (Homo sapiens)
Immune System (Homo sapiens)
Cytokine Signaling in Immune system (Homo sapiens)
Signaling by Interleukins (Homo sapiens)
Interleukin-1 family signaling (Homo sapiens)
Interleukin-1 processing (Homo sapiens)
Interleukin-1 family are secreted (Homo sapiens)
GSDMD pore complex [plasma membrane] (Homo sapiens)
Innate Immune System (Homo sapiens)
Toll-like Receptor Cascades (Homo sapiens)
Regulation of TLR by endogenous ligand (Homo sapiens)
HMGB1 release from cells (Homo sapiens)
GSDMD pore complex [plasma membrane] (Homo sapiens)
Programmed Cell Death (Homo sapiens)
Regulated Necrosis (Homo sapiens)
Pyroptosis (Homo sapiens)
GSDMD forms ring‐shaped oligomers (Homo sapiens)
GSDMD pore complex [plasma membrane] (Homo sapiens)
HMGB1 release from cells (Homo sapiens)
GSDMD pore complex [plasma membrane] (Homo sapiens)
Interleukin-1 family are secreted (Homo sapiens)
GSDMD pore complex [plasma membrane] (Homo sapiens)
Participants
components
x 3
GSDMD oligomer:PIPs [plasma membrane]
(Homo sapiens)
Participates
as an output of
GSDMD forms ring‐shaped oligomers (Homo sapiens)
This entity regulates
Positively
Interleukin-1 family are secreted
(Homo sapiens)
HMGB1 release from cells
(Homo sapiens)
Inferred To
GSDMD pore complex [plasma membrane]
(Bos taurus)
GSDMD pore complex [plasma membrane]
(Canis familiaris)
GSDMD pore complex [plasma membrane]
(Gallus gallus)
GSDMD pore complex [plasma membrane]
(Mus musculus)
GSDMD pore complex [plasma membrane]
(Rattus norvegicus)
GSDMD pore complex [plasma membrane]
(Sus scrofa)
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