Reactome | NMUR2 [plasma membrane]

NMUR2 [plasma membrane]

Stable Identifier

R-HSA-964816

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

plasma membrane

Synonyms

Neuromedin-U receptor 2, NMUR2_HUMAN

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:Q9GZQ4 NMUR2

Gene Names

NMUR2, NMU2R, TGR1

Chain

chain:1-415

Reference Genes

BioGPS Gene:56923 NMUR2

COSMIC (genes):NMUR2 NMUR2

CTD Gene:56923 NMUR2

dbSNP Gene:56923 NMUR2

ENSEMBL:ENSG00000132911 NMUR2

HGNC:16454 NMUR2

KEGG:hsa:56923 NMUR2

Monarch:56923 NMUR2

NCBI Gene:56923 NMUR2

OMIM:605108 NMUR2

UCSC:Q9GZQ4 NMUR2

Reference Transcript

RefSeq:NM_020167.4 NMUR2

Other Identifiers

11729497_at

11729498_at

17001976

224088_PM_at

224088_at

2882349

2882350

2882351

2882352

2882353

2882354

2882356

2882357

2882362

2882363

56923

62747_at

8115368

A_23_P122134

GE82509

GO:0001607

GO:0002023

GO:0004930

GO:0005215

GO:0005229

GO:0005515

GO:0005525

GO:0005886

GO:0006940

GO:0007186

GO:0007200

GO:0007218

GO:0007267

GO:0007417

GO:0007625

GO:0007631

GO:0008188

GO:0016020

GO:0023052

GO:0042924

GO:0048265

GO:0048856

GO:0050482

GO:0050850

GO:0055085

GO:0060089

GO:1902476

HMNXSV003044550

ILMN_1675009

PH_hs_0014602

TC05001963.hg

g10946202_3p_at

Participates

as a member of

as an input of

NMUR2 binds neuromedin-S (Homo sapiens)

as a component of

NMUR2:NMS [plasma membrane] (Homo sapiens)

Inferred To

NMUR2 [plasma membrane] (Bos taurus)

NMUR2 [plasma membrane] (Canis familiaris)

NMUR2 [plasma membrane] (Gallus gallus)

NMUR2 [plasma membrane] (Sus scrofa)

Nmur2 [plasma membrane] (Mus musculus)

Nmur2 [plasma membrane] (Rattus norvegicus)

PK2-R1 [plasma membrane] (Drosophila melanogaster)

nmur-1 [plasma membrane] (Caenorhabditis elegans)

nmur-2 [plasma membrane] (Caenorhabditis elegans)

sphr-1 [plasma membrane] (Caenorhabditis elegans)

npr-20 [plasma membrane] (Caenorhabditis elegans)

PK1-R [plasma membrane] (Drosophila melanogaster)

CapaR [plasma membrane] (Drosophila melanogaster)

nmur2 [plasma membrane] (Xenopus tropicalis)

Homologues of NMUR2 [plasma membrane] (Caenorhabditis elegans)

Homologues of NMUR2 [plasma membrane] (Drosophila melanogaster)

PK2-R2 [plasma membrane] (Drosophila melanogaster)

Cross References

RefSeq

NP_064552.3

Guide to Pharmacology - Targets

299

ENSEMBL

ENSG00000132911, ENST00000255262, ENSP00000255262

OpenTargets

ENSG00000132911

ZINC - Substances

NMUR2_HUMAN

ZINC - Biogenic

NMUR2_HUMAN

ZINC target

Q9GZQ4

PRO

Q9GZQ4

GlyGen

Q9GZQ4

PDB

7XK8, 7W57, 7W55

ZINC - Metabolites

NMUR2_HUMAN

GeneCards

NMUR2

HPA

ENSG00000132911-NMUR2

Pharos - Targets

Q9GZQ4

ZINC - Predictions - Purchasable

NMUR2_HUMAN

Interactors (14)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
IntAct:EBI-10178716 140258			0.556	3
UniProt:P15884 TCF4	1	TCF4 [nucleoplasm] (R-HSA-445672)	0.556	3
UniProt:Q6UY14-3 ADAMTSL4			0.556	3
UniProt:Q12933 TRAF2	5	TRAF2 [cytosol] (R-HSA-66370) PolyUb-TRAF2 [cytosol] (R-HSA-6782848) K63polyUb-TRAF2 [cytosol] (R-HSA-8862193) K63polyUb-TRAF2 [nucleoplasm] (R-HSA-8862194) TRAF2 [nucleoplasm] (R-HSA-8862199)	0.556	3
UniProt:Q7Z695 ADCK2			0.527	2
UniProt:Q9NV66 TYW1	1	TYW1 [cytoplasm] (R-HSA-6782884)	0.527	2
UniProt:Q9BXP2 S12A9			0.527	2
UniProt:Q8WUD6 CHPT1	1	CHPT1 [Golgi membrane] (R-HSA-1498754)	0.527	2
UniProt:Q9Y666 SLC12A7	1	SLC12A7 [plasma membrane] (R-HSA-426164)	0.527	2
UniProt:Q6NSJ5 LRRC8E	1	LRRC8E [plasma membrane] (R-HSA-8941539)	0.527	2
UniProt:Q9H819 DJC18			0.527	2
UniProt:Q9UL54 TAOK2			0.527	2
UniProt:P01877 IGHA2	1	IGHA2 [extracellular region] (R-HSA-1478812)	0.527	2
UniProt:Q7Z3S9 NOTCH2NLA	3	NOTCH2NLA [extracellular region] (R-HSA-9908935) NOTCH2NLA(1-?) [extracellular region] (R-HSA-9911493) NOTCH2NLA(?-236) [extracellular region] (R-HSA-9911490)	0.488	2