KCNQ4 located on the basal membrane of outer hair cells (OHCs) and the basolateral membrane of inner hair cells (inferred from the mouse homolog) transports potassium ions along the concentration gradient from the cytosol to the extracellular region (Kubisch et al. 1999 and inferred from the mouse homolog). The resulting efflux of potassium is believed to be responsible for the I(K,n) current that plays a role in setting the resting potential of the cell and in repolarization of the cell. Absence of KCNQ4 causes increased depolarization and degeneration of OHCs (inferred from the mouse homolog).
voltage-gated potassium channel activity of KCNQ4 tetramer [plasma membrane]