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SYN1 [clathrin-sculpted glutamate transport vesicle membrane]
Stable Identifier
R-HSA-9659624
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
clathrin-sculpted glutamate transport vesicle membrane
Synonyms
Synapsin-1, SYN1_HUMAN
Locations in the PathwayBrowser
Expand all
Sensory Perception (Homo sapiens)
Sensory processing of sound (Homo sapiens)
Sensory processing of sound by inner hair cells of the cochlea (Homo sapiens)
Exocytosis of glutamate from cochlear inner hair cell (Homo sapiens)
Glutamate depleted vesicle:Ca2+:SNAP25:STX1A [plasma membrane] (Homo sapiens)
Glutamate depleted synaptic vesicle (cochlear inner hair cell) [cytosol] (Homo sapiens)
SYN1 [clathrin-sculpted glutamate transport vesicle membrane] (Homo sapiens)
Glutamate loaded vesicle:BSN:RIBEYE:PICCOLINO [cytosol] (Homo sapiens)
Glutamate loaded synaptic vesicle (cochlear inner hair cell) [cytosol] (Homo sapiens)
SYN1 [clathrin-sculpted glutamate transport vesicle membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:P17600 SYN1
Gene Names
SYN1
Chain
chain:1-705
Reference Genes
BioGPS Gene:6853 SYN1
COSMIC (genes):SYN1 SYN1
CTD Gene:6853 SYN1
dbSNP Gene:6853 SYN1
ENSEMBL:ENSG00000008056 SYN1
ENSEMBL_homo_sapiens_GENE:ENSG00000008056.14 SYN1
HGNC:11494 SYN1
KEGG Gene (Homo sapiens):6853 SYN1
Monarch:6853 SYN1
NCBI Gene:6853 SYN1
OMIM:313440 SYN1
UCSC:P17600 SYN1
Reference Transcript
RefSeq:NM_006950.3 SYN1
RefSeq:NM_133499.2 SYN1
Other Identifiers
11726133_a_at
1553264_PM_a_at
1553264_a_at
17110447
221914_PM_at
221914_at
32923_r_at
4007127
4007128
4007129
4007130
4007131
4007132
4007134
4007135
4007136
4007137
4007138
4007139
4007140
4007141
4007142
4007149
4007151
4007153
4007154
4007158
4007159
4007160
4007161
47050_at
6853
8172317
A_23_P33847
A_23_P500824
GE60549
GE80390
GO:0000228
GO:0000795
GO:0003779
GO:0005515
GO:0005524
GO:0005634
GO:0005694
GO:0005794
GO:0005856
GO:0007268
GO:0007269
GO:0008021
GO:0008092
GO:0014069
GO:0016192
GO:0019901
GO:0023052
GO:0030154
GO:0030424
GO:0030425
GO:0030672
GO:0031410
GO:0034330
GO:0042802
GO:0042995
GO:0043226
GO:0044297
GO:0045202
GO:0046928
GO:0048306
GO:0048666
GO:0048786
GO:0048856
GO:0050808
GO:0060090
GO:0097091
GO:0098685
GO:0098693
GO:0098793
GO:0098850
GO:0099504
GO:0106006
GO:2000300
HMNXSV003007635
Hs.225936.0.S2_3p_at
Hs2.225936.1.S1_3p_s_at
ILMN_1660693
ILMN_1783837
ILMN_2407703
M58378_cds1_at
PH_hs_0035705
TC0X000997.hg
Participates
as a component of
Glutamate depleted synaptic vesicle (cochlear inner hair cell) [cytosol] (Homo sapiens)
Glutamate loaded synaptic vesicle (cochlear inner hair cell) [cytosol] (Homo sapiens)
Other forms of this molecule
SYN1 [clathrin-sculpted monoamine transport vesicle membrane]
Cross References
RefSeq
NP_008881.2
,
NP_598006.1
OpenTargets
ENSG00000008056
GeneCards
P17600
HPA
ENSG00000008056-SYN1
Ensembl
ENST00000295987
,
ENST00000340666
,
ENSP00000295987
,
ENSG00000008056
,
ENSP00000343206
PRO
P17600
Pharos - Targets
P17600
Orphanet
15573
Interactors (1)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P00533 EGFR
20
p-6Y-EGFR [clathrin-coated endocytic vesicle membrane]
(R-HSA-8869138)
p-5Y-EGFRvIII [plasma membrane]
(R-HSA-1248649)
EGFRvIII [plasma membrane]
(R-HSA-1214162)
p-6Y-EGFR E746_A750del;T790M [plasma membrane]
(R-HSA-1182985)
p-6Y-EGFR L858R;T790M [plasma membrane]
(R-HSA-1182984)
p-6Y-EGFR A767_V769dup [plasma membrane]
(R-HSA-1996343)
p-6Y-EGFR N771_H773dup [plasma membrane]
(R-HSA-1996342)
p-6Y-EGFR K739_I744dup [plasma membrane]
(R-HSA-1996346)
p-6Y-EGFR D770_N771insNPG [plasma membrane]
(R-HSA-1996335)
p-6Y-EGFR E746_A750del [plasma membrane]
(R-HSA-1181214)
p-6Y-EGFR L858R [plasma membrane]
(R-HSA-1173211)
p-6Y-EGFR G719S [plasma membrane]
(R-HSA-1169417)
p-6Y-EGFR L747_P753delinsS [plasma membrane]
(R-HSA-1228038)
p-6Y-EGFR L747_A750delinsP [plasma membrane]
(R-HSA-1228044)
p-6Y-EGFR L747_T751del [plasma membrane]
(R-HSA-1228041)
p-6Y-EGFR L747_S752del [plasma membrane]
(R-HSA-1228040)
p-6Y-EGFR L747_T751delinsP [plasma membrane]
(R-HSA-1228042)
p-6Y-EGFR E746_T751delinsA [plasma membrane]
(R-HSA-1228037)
p-6Y-EGFR E746_S752delinsV [plasma membrane]
(R-HSA-1228039)
p-6Y-EGFR L861Q [plasma membrane]
(R-HSA-1177541)
0.553
2
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