ATP binds P2RX4,7

Stable Identifier
R-HSA-9660822
Type
Reaction [binding]
Species
Homo sapiens
Compartment
extracellular region, plasma membrane
ReviewStatus
5/5
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 | PPTX  | SBGN
ATP binds P2RX4,7
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The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout
P2X receptors are a family of cation-permeable ligand gated ion channels that open in response to the binding of extracellular adenosine triphosphate (ATP) (Gicquel et al. 2015). All members of the family are thought to be functionally trimeric.
Literature References
PubMed ID Title Journal Year
26116704 IL-1β production is dependent on the activation of purinergic receptors and NLRP3 pathway in human macrophages

Ribault, C, Victoni, T, Gicquel, T, Gleonnec, F, Lagente, V, Bodin, A, Loyer, P, Couillin, I, Robert, S, Boichot, E

FASEB J. 2015
Participants
Input
Output
Participates
as an event of
Authored
Murillo, JI  (2020-01-07)
Jassal, B  (2020-01-07)
Reviewed
Gregory, DJ  (2020-02-04)
Created
Murillo, JI  (2019-09-12)
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