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p-T564-RDX [cytosol]
Stable Identifier
R-HSA-9662922
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
Radixin, RADI_HUMAN
Locations in the PathwayBrowser
Expand all
Sensory Perception (Homo sapiens)
Sensory processing of sound (Homo sapiens)
Sensory processing of sound by inner hair cells of the cochlea (Homo sapiens)
Mechanoelectrical transduction (MET) channel transports cations from the extracellular region into the cytosol of stereocilia of inner hair cell (Homo sapiens)
MET channel:Tip link:USH1C:USH1G:MYO7A:cytoskeleton (IHC) [plasma membrane] (Homo sapiens)
Inner hair cell stereocilium cytoskeleton [cytosol] (Homo sapiens)
Stereocilium shaft [cytosol] (Homo sapiens)
p-T564-RDX [cytosol] (Homo sapiens)
Sensory processing of sound by outer hair cells of the cochlea (Homo sapiens)
Mechanoelectrical transduction (MET) channel transports cations into the cytosol of stereocilia of cochlear outer hair cell (Homo sapiens)
MET channel:Tip link:USH1C:USH1G:MYO7A:cytoskeleton (OHC) [plasma membrane] (Homo sapiens)
Outer hair cell stereocilium cytoskeleton [cytosol] (Homo sapiens)
Stereocilium shaft [cytosol] (Homo sapiens)
p-T564-RDX [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:P35241 RDX
Gene Names
RDX
Chain
chain:1-583
Reference Genes
BioGPS Gene:5962 RDX
COSMIC (genes):RDX RDX
CTD Gene:5962 RDX
dbSNP Gene:5962 RDX
ENSEMBL:ENSG00000137710 RDX
HGNC:9944 RDX
Monarch:5962 RDX
NCBI Gene:5962 RDX
OMIM:179410 RDX
UCSC:P35241 RDX
Reference Transcript
RefSeq:NM_001260496.1 RDX
RefSeq:NM_001260492.1 RDX
RefSeq:NM_001260493.1 RDX
RefSeq:NM_001260494.1 RDX
RefSeq:NM_002906.3 RDX
RefSeq:NM_001260495.1 RDX
Other Identifiers
11717524_s_at
11717525_s_at
11717526_a_at
11717527_a_at
11748967_a_at
11748968_x_at
11759725_a_at
11761819_a_at
16744174
204969_PM_s_at
204969_s_at
212397_PM_at
212397_at
212398_PM_at
212398_at
244739_PM_at
244739_at
3360106
3390529
3390545
3390552
3390555
3390556
3390557
3390563
3390570
3390571
3390572
3390573
3390574
3390575
3390576
3390577
3390579
3390581
3390582
3390584
3390585
3390586
3390587
3390590
3390591
3390594
3390595
3390597
3390598
3390600
3390601
3390602
3390604
3390605
3390608
3390612
34886_at
34887_at
3972499
4003523
56730_at
5962
7951554
86296_at
A_19_P00317164
A_19_P00800682
A_23_P203023
A_33_P3423121
GE491397
GE81208
GO:0003723
GO:0003779
GO:0005515
GO:0005615
GO:0005737
GO:0005856
GO:0005886
GO:0005902
GO:0005912
GO:0005925
GO:0008092
GO:0008360
GO:0008361
GO:0010628
GO:0010737
GO:0016020
GO:0016324
GO:0030027
GO:0030175
GO:0030315
GO:0030335
GO:0030496
GO:0030864
GO:0032154
GO:0032231
GO:0032420
GO:0032487
GO:0034111
GO:0034260
GO:0036120
GO:0042995
GO:0043087
GO:0043226
GO:0045176
GO:0045177
GO:0045296
GO:0045732
GO:0045792
GO:0048856
GO:0050839
GO:0051016
GO:0051018
GO:0051117
GO:0051286
GO:0051693
GO:0061028
GO:0061951
GO:0070062
GO:0071944
GO:0072659
GO:0097067
GO:0120044
GO:1900027
GO:1900087
GO:1902115
GO:1902966
GO:1903392
GO:2000643
HMNXSV003003266
HMNXSV003047070
Hs.263671.0.A1_3p_at
Hs.263671.0.A2_3p_at
Hs.96297.0.A1_3p_at
ILMN_1708611
L02320_at
PH_hs_0029542
TC11002274.hg
TC11003334.hg
g4506466_3p_s_at
Participates
as a component of
Stereocilium shaft [cytosol] (Homo sapiens)
Other forms of this molecule
RDX [cytosol]
Modified Residues
Name
O-phospho-L-threonine at 564
Coordinate
564
PsiMod Name
O-phospho-L-threonine [MOD:00047]
PsiMod Definition
A protein modification that effectively converts an L-threonine residue to O-phospho-L-threonine.
Cross References
ENSEMBL
ENST00000528900
,
ENST00000530749
,
ENSP00000436277
,
ENST00000530301
,
ENSP00000432112
,
ENSP00000437301
,
ENST00000645495
,
ENST00000647231
,
ENSP00000445826
,
ENSP00000433580
,
ENSP00000496414
,
ENSP00000496503
,
ENST00000528498
,
ENST00000544551
OpenTargets
ENSG00000137710
HPA
ENSG00000137710-RDX
PRO
P35241
Pharos - Targets
P35241
GlyGen
P35241
Orphanet
RDX
Interactors (5)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P15311 EZR
3
p-Y146,Y354-EZR [cytosol]
(R-HSA-374572)
p-T567-EZR [cytosol]
(R-HSA-374559)
EZR [cytosol]
(R-HSA-9020826)
0.813
10
UniProt:P13569 CFTR
17
misfolded CFTR [endoplasmic reticulum membrane]
(R-HSA-8868730)
CFTR [endoplasmic reticulum membrane]
(R-HSA-8866837)
CFTR [plasma membrane]
(R-HSA-383188)
CFTR N1303K [plasma membrane]
(R-HSA-5678983)
CFTR F508del [plasma membrane]
(R-HSA-5678978)
CFTR W1282* [plasma membrane]
(R-HSA-5678976)
CFTR G551D [plasma membrane]
(R-HSA-5678977)
CFTR G542* [plasma membrane]
(R-HSA-5678986)
ub-CFTR F508del [endoplasmic reticulum membrane]
(R-HSA-8866842)
ub-CFTR F508del [cytosol]
(R-HSA-8866838)
CFTR F508del [endoplasmic reticulum membrane]
(R-HSA-8866834)
PolyUb-CFTR [endosome membrane]
(R-HSA-6782976)
CFTR [endosome membrane]
(R-HSA-6782965)
CFTR [Golgi-associated vesicle membrane]
(R-HSA-5627079)
CFTR [lysosomal membrane]
(R-HSA-5627279)
PolyUb-CFTR [plasma membrane]
(R-HSA-8867595)
PolyUb-CFTR [clathrin-coated endocytic vesicle membrane]
(R-HSA-8869104)
0.615
10
UniProt:P10911 MCF2
1
MCF2 [cytosol]
(R-HSA-3006639)
0.544
2
UniProt:P52565 ARHGDIA
1
ARHGDIA [cytosol]
(R-HSA-194478)
0.544
2
UniProt:P26038 MSN
4
MSN [cytosol]
(R-HSA-437350)
MSN(2-448)-ALK(1064-1620) fusion [cytosol]
(R-HSA-9711966)
MSN(2-448)-p-7Y-ALK(1064-1620) fusion [cytosol]
(R-HSA-9711971)
p-T558-MSN [cytosol]
(R-HSA-9663005)
0.527
2
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