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LEMD2:ESCRT-III:IST1 [nuclear envelope]
Stable Identifier
R-HSA-9668518
Type
Complex
Species
Homo sapiens
Compartment
nuclear envelope
Locations in the PathwayBrowser
Expand all
Cell Cycle (Homo sapiens)
Cell Cycle, Mitotic (Homo sapiens)
M Phase (Homo sapiens)
Mitotic Metaphase and Anaphase (Homo sapiens)
Mitotic Anaphase (Homo sapiens)
Nuclear Envelope (NE) Reassembly (Homo sapiens)
Sealing of the nuclear envelope (NE) by ESCRT-III (Homo sapiens)
CHMP7 binds CC2D1B (Homo sapiens)
LEM2D:ESCRT-III:IST1:CC2D1B [nuclear envelope] (Homo sapiens)
LEMD2:ESCRT-III:IST1 [nuclear envelope] (Homo sapiens)
LEMD2:ESCRT-III:IST1 [nuclear envelope] (Homo sapiens)
CHMP7 binds CHMP4B, which recruits other subunits of the ESCRT-III complex (Homo sapiens)
LEMD2:ESCRT-III:IST1 [nuclear envelope] (Homo sapiens)
SPAST (spastin) binds the IST1 subunit of ESCRT-III at the sites of microtubule attachment to chromatin (Homo sapiens)
LEM2D:ESCRT-III:IST1:CC2D1B [nuclear envelope] (Homo sapiens)
LEMD2:ESCRT-III:IST1 [nuclear envelope] (Homo sapiens)
LEM2D:ESCRT-III:IST1:CC2D1B:SPAST [nuclear envelope] (Homo sapiens)
LEM2D:ESCRT-III:IST1:CC2D1B [nuclear envelope] (Homo sapiens)
LEMD2:ESCRT-III:IST1 [nuclear envelope] (Homo sapiens)
SPAST (spastin) mediates the severing of microtubules at chromosome attachment sites (Homo sapiens)
LEM2D:ESCRT-III:IST1:CC2D1B:SPAST [nuclear envelope] (Homo sapiens)
LEM2D:ESCRT-III:IST1:CC2D1B [nuclear envelope] (Homo sapiens)
LEMD2:ESCRT-III:IST1 [nuclear envelope] (Homo sapiens)
VPS4 binds ESCRT-III assemblies at nuclear envelope (NE) fenestrations (Homo sapiens)
LEM2D:ESCRT-III:IST1:CC2D1B:SPAST [nuclear envelope] (Homo sapiens)
LEM2D:ESCRT-III:IST1:CC2D1B [nuclear envelope] (Homo sapiens)
LEMD2:ESCRT-III:IST1 [nuclear envelope] (Homo sapiens)
LEM2D:ESCRT-III:IST1:CC2D1B:SPAST:VPS4A [nuclear envelope] (Homo sapiens)
LEM2D:ESCRT-III:IST1:CC2D1B:SPAST [nuclear envelope] (Homo sapiens)
LEM2D:ESCRT-III:IST1:CC2D1B [nuclear envelope] (Homo sapiens)
LEMD2:ESCRT-III:IST1 [nuclear envelope] (Homo sapiens)
VPS4 mediates disassembly of ESCRTIII subunits to promote sealing of holes in the nuclear envelope (Homo sapiens)
LEM2D:ESCRT-III:IST1:CC2D1B:SPAST:VPS4A [nuclear envelope] (Homo sapiens)
LEM2D:ESCRT-III:IST1:CC2D1B:SPAST [nuclear envelope] (Homo sapiens)
LEM2D:ESCRT-III:IST1:CC2D1B [nuclear envelope] (Homo sapiens)
LEMD2:ESCRT-III:IST1 [nuclear envelope] (Homo sapiens)
Participants
components
ESCRT-III [cytosol]
(Homo sapiens)
IST1 [cytosol]
(Homo sapiens)
LEMD2 [nuclear envelope]
(Homo sapiens)
Participates
as an output of
CHMP7 binds CHMP4B, which recruits other subunits of the ESCRT-III complex (Homo sapiens)
as an input of
CHMP7 binds CC2D1B (Homo sapiens)
as a component of
LEM2D:ESCRT-III:IST1:CC2D1B [nuclear envelope] (Homo sapiens)
Inferred To
LEMD2:ESCRT-III:IST1 [nuclear envelope]
(Bos taurus)
LEMD2:ESCRT-III:IST1 [nuclear envelope]
(Caenorhabditis elegans)
LEMD2:ESCRT-III:IST1 [nuclear envelope]
(Canis familiaris)
LEMD2:ESCRT-III:IST1 [nuclear envelope]
(Danio rerio)
LEMD2:ESCRT-III:IST1 [nuclear envelope]
(Dictyostelium discoideum)
LEMD2:ESCRT-III:IST1 [nuclear envelope]
(Drosophila melanogaster)
LEMD2:ESCRT-III:IST1 [nuclear envelope]
(Gallus gallus)
LEMD2:ESCRT-III:IST1 [nuclear envelope]
(Mus musculus)
LEMD2:ESCRT-III:IST1 [nuclear envelope]
(Rattus norvegicus)
LEMD2:ESCRT-III:IST1 [nuclear envelope]
(Saccharomyces cerevisiae)
LEMD2:ESCRT-III:IST1 [nuclear envelope]
(Schizosaccharomyces pombe)
LEMD2:ESCRT-III:IST1 [nuclear envelope]
(Sus scrofa)
LEMD2:ESCRT-III:IST1 [nuclear envelope]
(Xenopus tropicalis)
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