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p7Y-juxtamembrane domain KIT mutant dimers [plasma membrane]
Stable Identifier
R-HSA-9669816
Type
Set [CandidateSet]
Species
Homo sapiens
Compartment
plasma membrane
Locations in the PathwayBrowser
Expand all
Disease (Homo sapiens)
Diseases of signal transduction by growth factor receptors and second messengers (Homo sapiens)
Signaling by KIT in disease (Homo sapiens)
Signaling by juxtamembrane domain KIT mutants (Homo sapiens)
Phosphorylation of juxtamembrane domain KIT mutants (Homo sapiens)
p7Y-juxtamembrane domain KIT mutant dimers [plasma membrane] (Homo sapiens)
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants (Homo sapiens)
Dimerization of STATs downstream of KIT mutants (Homo sapiens)
p-JAK2:SFKs:p-KIT mutants:p-STAT dimers [plasma membrane] (Homo sapiens)
KIT mutant dimers:SFKs [plasma membrane] (Homo sapiens)
p7Y-KIT kinase, extracellular and juxtamembrane domain dimers [plasma membrane] (Homo sapiens)
p7Y-juxtamembrane domain KIT mutant dimers [plasma membrane] (Homo sapiens)
p-JAK2:SFKs:p-KIT mutants:p-STATs [plasma membrane] (Homo sapiens)
KIT mutant dimers:SFKs [plasma membrane] (Homo sapiens)
p7Y-KIT kinase, extracellular and juxtamembrane domain dimers [plasma membrane] (Homo sapiens)
p7Y-juxtamembrane domain KIT mutant dimers [plasma membrane] (Homo sapiens)
Disassociation and translocation of STATs to the nucleus downstream of KIT mutants (Homo sapiens)
KIT mutant dimers:SFKs:p-JAK2 [plasma membrane] (Homo sapiens)
KIT mutant dimers:SFKs [plasma membrane] (Homo sapiens)
p7Y-KIT kinase, extracellular and juxtamembrane domain dimers [plasma membrane] (Homo sapiens)
p7Y-juxtamembrane domain KIT mutant dimers [plasma membrane] (Homo sapiens)
p-JAK2:SFKs:p-KIT mutants:p-STAT dimers [plasma membrane] (Homo sapiens)
KIT mutant dimers:SFKs [plasma membrane] (Homo sapiens)
p7Y-KIT kinase, extracellular and juxtamembrane domain dimers [plasma membrane] (Homo sapiens)
p7Y-juxtamembrane domain KIT mutant dimers [plasma membrane] (Homo sapiens)
JAK2 binds to p-KIT mutants (Homo sapiens)
KIT mutant dimers:SFKs [plasma membrane] (Homo sapiens)
p7Y-KIT kinase, extracellular and juxtamembrane domain dimers [plasma membrane] (Homo sapiens)
p7Y-juxtamembrane domain KIT mutant dimers [plasma membrane] (Homo sapiens)
KIT mutant dimers:SFKs:JAK2 [plasma membrane] (Homo sapiens)
p7Y-KIT kinase, extracellular and juxtamembrane domain dimers [plasma membrane] (Homo sapiens)
p7Y-juxtamembrane domain KIT mutant dimers [plasma membrane] (Homo sapiens)
KIT mutants bind GRB2-SOS (Homo sapiens)
p-KIT mutants:GRB2:SOS [plasma membrane] (Homo sapiens)
p7Y-KIT kinase, extracellular and juxtamembrane domain dimers [plasma membrane] (Homo sapiens)
p7Y-juxtamembrane domain KIT mutant dimers [plasma membrane] (Homo sapiens)
p7Y-KIT kinase, extracellular and juxtamembrane domain dimers [plasma membrane] (Homo sapiens)
p7Y-juxtamembrane domain KIT mutant dimers [plasma membrane] (Homo sapiens)
KIT mutants bind SFKs (Homo sapiens)
KIT mutant dimers:SFKs [plasma membrane] (Homo sapiens)
p7Y-KIT kinase, extracellular and juxtamembrane domain dimers [plasma membrane] (Homo sapiens)
p7Y-juxtamembrane domain KIT mutant dimers [plasma membrane] (Homo sapiens)
p7Y-KIT kinase, extracellular and juxtamembrane domain dimers [plasma membrane] (Homo sapiens)
p7Y-juxtamembrane domain KIT mutant dimers [plasma membrane] (Homo sapiens)
KIT mutants:PI3K catalyze synthesis of PIP3 (Homo sapiens)
PI3K:p-KIT mutant dimers [plasma membrane] (Homo sapiens)
p7Y-KIT kinase, extracellular and juxtamembrane domain dimers [plasma membrane] (Homo sapiens)
p7Y-juxtamembrane domain KIT mutant dimers [plasma membrane] (Homo sapiens)
Phosphorylated KIT mutants bind PI3K (Homo sapiens)
PI3K:p-KIT mutant dimers [plasma membrane] (Homo sapiens)
p7Y-KIT kinase, extracellular and juxtamembrane domain dimers [plasma membrane] (Homo sapiens)
p7Y-juxtamembrane domain KIT mutant dimers [plasma membrane] (Homo sapiens)
p7Y-KIT kinase, extracellular and juxtamembrane domain dimers [plasma membrane] (Homo sapiens)
p7Y-juxtamembrane domain KIT mutant dimers [plasma membrane] (Homo sapiens)
Phosphorylation of JAK2 downstream of KIT mutants (Homo sapiens)
KIT mutant dimers:SFKs:JAK2 [plasma membrane] (Homo sapiens)
p7Y-KIT kinase, extracellular and juxtamembrane domain dimers [plasma membrane] (Homo sapiens)
p7Y-juxtamembrane domain KIT mutant dimers [plasma membrane] (Homo sapiens)
KIT mutant dimers:SFKs:p-JAK2 [plasma membrane] (Homo sapiens)
KIT mutant dimers:SFKs [plasma membrane] (Homo sapiens)
p7Y-KIT kinase, extracellular and juxtamembrane domain dimers [plasma membrane] (Homo sapiens)
p7Y-juxtamembrane domain KIT mutant dimers [plasma membrane] (Homo sapiens)
Phosphorylation of STATs downstream of KIT mutants (Homo sapiens)
KIT mutant dimers:SFKs:p-JAK2:STATs [plasma membrane] (Homo sapiens)
KIT mutant dimers:SFKs:p-JAK2 [plasma membrane] (Homo sapiens)
KIT mutant dimers:SFKs [plasma membrane] (Homo sapiens)
p7Y-KIT kinase, extracellular and juxtamembrane domain dimers [plasma membrane] (Homo sapiens)
p7Y-juxtamembrane domain KIT mutant dimers [plasma membrane] (Homo sapiens)
p-JAK2:SFKs:p-KIT mutants:p-STATs [plasma membrane] (Homo sapiens)
KIT mutant dimers:SFKs [plasma membrane] (Homo sapiens)
p7Y-KIT kinase, extracellular and juxtamembrane domain dimers [plasma membrane] (Homo sapiens)
p7Y-juxtamembrane domain KIT mutant dimers [plasma membrane] (Homo sapiens)
Recruitment of STATs by KIT mutants (Homo sapiens)
KIT mutant dimers:SFKs:p-JAK2 [plasma membrane] (Homo sapiens)
KIT mutant dimers:SFKs [plasma membrane] (Homo sapiens)
p7Y-KIT kinase, extracellular and juxtamembrane domain dimers [plasma membrane] (Homo sapiens)
p7Y-juxtamembrane domain KIT mutant dimers [plasma membrane] (Homo sapiens)
KIT mutant dimers:SFKs:p-JAK2:STATs [plasma membrane] (Homo sapiens)
KIT mutant dimers:SFKs:p-JAK2 [plasma membrane] (Homo sapiens)
KIT mutant dimers:SFKs [plasma membrane] (Homo sapiens)
p7Y-KIT kinase, extracellular and juxtamembrane domain dimers [plasma membrane] (Homo sapiens)
p7Y-juxtamembrane domain KIT mutant dimers [plasma membrane] (Homo sapiens)
p-KIT mutants:GRB2:SOS catalyzes nucleotide exchange on RAS (Homo sapiens)
p-KIT mutants:GRB2:SOS [plasma membrane] (Homo sapiens)
p7Y-KIT kinase, extracellular and juxtamembrane domain dimers [plasma membrane] (Homo sapiens)
p7Y-juxtamembrane domain KIT mutant dimers [plasma membrane] (Homo sapiens)
Participants
members
p7Y-KIT K550I P551_V555del dimer [plasma membrane]
(Homo sapiens)
p7Y-KIT K550_K558del dimer [plasma membrane]
(Homo sapiens)
p7Y-KIT L576P dimer [plasma membrane]
(Homo sapiens)
p7Y-KIT P551_V555del dimer [plasma membrane]
(Homo sapiens)
p7Y-KIT V559D dimer [plasma membrane]
(Homo sapiens)
p7Y-KIT V559_V560del dimer [plasma membrane]
(Homo sapiens)
p7Y-KIT V560G dimer [plasma membrane]
(Homo sapiens)
p7Y-KIT W557_K558del dimer [plasma membrane]
(Homo sapiens)
p5Y-KIT V560_L576del dimer [plasma membrane]
(Homo sapiens)
candidates
p7Y-KIT V559A dimer [plasma membrane]
(Homo sapiens)
p7Y-KIT V559G dimer [plasma membrane]
(Homo sapiens)
p7Y-KIT V559I dimer [plasma membrane]
(Homo sapiens)
p7Y-KIT V560D dimer [plasma membrane]
(Homo sapiens)
p7Y-KIT V560E dimer [plasma membrane]
(Homo sapiens)
p7Y-KIT W557G dimer [plasma membrane]
(Homo sapiens)
p7Y-KIT W557R dimer [plasma membrane]
(Homo sapiens)
Participates
as an output of
Phosphorylation of juxtamembrane domain KIT mutants (Homo sapiens)
as a member of
p7Y-KIT kinase, extracellular and juxtamembrane domain dimers [plasma membrane] (Homo sapiens)
Disease
Name
Identifier
Synonyms
cancer
DOID:162
malignant tumor, malignant neoplasm, primary cancer
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