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ZCRB1 [cytosol]
Stable Identifier
R-HSA-9682010
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
Zinc finger CCHC-type and RNA-binding motif-containing protein 1, ZCRB1_HUMAN
Locations in the PathwayBrowser for interactor UniProt:O60832 DKC1
Expand all
Disease (Homo sapiens)
Infectious disease (Homo sapiens)
Viral Infection Pathways (Homo sapiens)
SARS-CoV Infections (Homo sapiens)
SARS-CoV-1 Infection (Homo sapiens)
SARS-CoV-1 Genome Replication and Transcription (Homo sapiens)
Replication of the SARS-CoV-1 genome (Homo sapiens)
ZCRB1 binds 5'UTR of SARS-CoV-1 genomic RNA (Homo sapiens)
ZCRB1 [cytosol] (Homo sapiens)
SARS-CoV-2 Infection (Homo sapiens)
Early SARS-CoV-2 Infection Events (Homo sapiens)
SARS-CoV-2 Genome Replication and Transcription (Homo sapiens)
Replication of the SARS-CoV-2 genome (Homo sapiens)
ZCRB1 binds 5'UTR of SARS-CoV-2 genomic RNA (Homo sapiens)
ZCRB1 [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q8TBF4 ZCRB1
Gene Names
ZCRB1
Chain
chain:1-217
Reference Genes
BioGPS Gene:85437 ZCRB1
COSMIC (genes):ZCRB1 ZCRB1
CTD Gene:85437 ZCRB1
dbSNP Gene:85437 ZCRB1
ENSEMBL:ENSG00000139168 ZCRB1
ENSEMBL_homo_sapiens_GENE:ENSG00000139168.9 ZCRB1
HGNC:29620 ZCRB1
KEGG Gene (Homo sapiens):85437 ZCRB1
Monarch:85437 ZCRB1
NCBI Gene:85437 ZCRB1
OMIM:610750 ZCRB1
UCSC:Q8TBF4 ZCRB1
Reference Transcript
RefSeq:NM_033114.3 ZCRB1
Other Identifiers
11732161_at
11732162_at
11732163_x_at
16763280
225394_PM_s_at
225394_s_at
227416_PM_s_at
227416_s_at
3451319
3451320
3451321
3451323
3451324
3451325
3451326
3451327
3451328
3451332
3451333
3451335
3451336
3451337
3451338
3451339
3451340
3451341
4011927
4011928
46727_at
7962367
85437
A_24_P4877
GE79824
GO:0000398
GO:0003676
GO:0003723
GO:0005515
GO:0005634
GO:0005654
GO:0005681
GO:0005689
GO:0005829
GO:0006397
GO:0008270
GO:0008380
GO:0016071
GO:0043226
GO:0046872
HMNXSV003053634
Hs.43847.0.S1_3p_x_at
Hs.43847.1.S1_3p_a_at
ILMN_1659082
PH_hs_0003181
PH_hs_0031195
TC12001403.hg
Participates
as a component of
ZCRB1:m7G(5')pppAm-capped, polyadenylated SARS-CoV-2 genomic RNA (plus strand) [cytosol] (Homo sapiens)
ZCRB1:SARS-CoV-1 genomic RNA (plus strand) [cytosol] (Homo sapiens)
as an input of
ZCRB1 binds 5'UTR of SARS-CoV-2 genomic RNA (Homo sapiens)
ZCRB1 binds 5'UTR of SARS-CoV-1 genomic RNA (Homo sapiens)
Other forms of this molecule
ZCRB1 [nucleoplasm]
Cross References
RefSeq
NP_149105.3
OpenTargets
ENSG00000139168
HPA
ENSG00000139168-ZCRB1
GeneCards
Q8TBF4
Ensembl
ENSG00000139168
,
ENST00000679269
,
ENSP00000503171
,
ENST00000677694
,
ENSP00000503413
,
ENST00000266529
,
ENSP00000266529
PRO
Q8TBF4
Pharos - Targets
Q8TBF4
PDB
2E5H
Interactors (47)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q13435 SF3B2
1
SF3B2 [nucleoplasm]
(R-HSA-71971)
0.643
4
UniProt:O75533 SF3B1
1
SF3B1 [nucleoplasm]
(R-HSA-71968)
0.643
4
UniProt:P04792 HSBP1
3
HSPB1 [cytosol]
(R-HSA-450563)
p-S15,S78,S82-HSP27 [cytosol]
(R-HSA-5218697)
p-S78,S82 HSPB1 [cytosol]
(R-HSA-5687009)
0.556
3
UniProt:O43933 PEX1
1
PEX1 [cytosol]
(R-HSA-9033116)
0.556
3
UniProt:O76024 WFS1
3
WFS1 [endoplasmic reticulum lumen]
(R-HSA-8956747)
p-WFS1 [endoplasmic reticulum lumen]
(R-HSA-8956998)
WFS1 [endoplasmic reticulum membrane]
(R-HSA-535474)
0.556
3
UniProt:Q6IEG0 SNRNP48
1
SNRNP48 [nucleoplasm]
(R-HSA-6787849)
0.527
3
UniProt:Q9NZM5 NOP53
0.527
2
UniProt:Q9Y4C8 RBM19
0.527
2
UniProt:Q9BXY0 MAK16
0.527
2
UniProt:Q96LT9 RNPC3
1
RNPC3 [nucleoplasm]
(R-HSA-6787844)
0.527
3
UniProt:Q9BRU9 UTP23
0.527
2
UniProt:Q9UDW3 ZMAT5
1
ZMAT5 [nucleoplasm]
(R-HSA-6787850)
0.527
3
UniProt:P84098 RPL19
1
RPL19 [cytosol]
(R-HSA-72424)
0.527
3
UniProt:Q8N9T8 KRI1
0.527
3
UniProt:P23396 RPS3
2
RPS3 [nucleoplasm]
(R-HSA-6798714)
RPS3 [cytosol]
(R-HSA-72369)
0.527
2
UniProt:O95625 ZBT11
0.527
2
UniProt:Q8N5P1 ZC3H8
1
ZC3H8 [nucleoplasm]
(R-HSA-6807406)
0.527
2
UniProt:Q15695 U2AFL
0.527
3
UniProt:Q9H9Y2 RPF1
0.527
2
UniProt:P14678 SNRPB
4
SNRPB [nucleoplasm]
(R-HSA-71896)
Me2-R108,R112-SNRPB [nucleoplasm]
(R-HSA-192213)
SNRPB [cytosol]
(R-HSA-191798)
2xMe-SNRPB [cytosol]
(R-HSA-192218)
0.527
2
UniProt:Q6PKG0 LARP1
1
LARP1 [cytosol]
(R-HSA-9760421)
0.527
2
UniProt:Q15050 RRS1
0.527
2
UniProt:Q02539 H1-1
1
HIST1H1A [nucleoplasm]
(R-HSA-211245)
0.527
3
UniProt:Q8N8D1 PDCD7
1
PDCD7 [nucleoplasm]
(R-HSA-6787851)
0.527
3
UniProt:Q00577 PURA
0.527
2
UniProt:P10412 H1-4
1
HIST1H1E [nucleoplasm]
(R-HSA-211251)
0.527
3
UniProt:P22492 H1T
0.527
3
UniProt:Q15527 SURF2
0.527
3
UniProt:Q4G0J3 LARP7
0.527
3
UniProt:P49711 CTCF
1
CTCF [nucleoplasm]
(R-HSA-3782562)
0.527
2
UniProt:P08865 RPSA
2
RPSA [nucleoplasm]
(R-HSA-6798722)
RPSA [cytosol]
(R-HSA-72389)
0.527
3
UniProt:Q9Y2T7 YBOX2
0.527
2
UniProt:Q9BYG3 MK67I
0.527
3
UniProt:Q96HE9 PRR11
0.527
2
UniProt:P61247 RPS3A
2
RPS3A [nucleoplasm]
(R-HSA-6791182)
RPS3A [cytosol]
(R-HSA-72373)
0.527
3
UniProt:P67809 YBX1
5
p-S32,S36-YBX1 [nucleoplasm]
(R-HSA-9733227)
p-S32,S36-YBX1 [cytosol]
(R-HSA-9736837)
YBX1 [cytosol]
(R-HSA-9736840)
YBX1 [nucleoplasm]
(R-HSA-72041)
YBX1 [extracellular region]
(R-HSA-9017791)
0.527
2
UniProt:P62306 SNRPF
2
SNRPF [nucleoplasm]
(R-HSA-71907)
SNRPF [cytosol]
(R-HSA-191852)
0.527
3
UniProt:O95363 FARS2
1
FARS2(1-?) [mitochondrial matrix]
(R-HSA-379565)
0.527
2
UniProt:P15880 RPS2
3
RPS2 [nucleoplasm]
(R-HSA-6790655)
Me2aR-RPS2 [cytosol]
(R-HSA-8879138)
RPS2 [cytosol]
(R-HSA-72347)
0.527
3
UniProt:P46782 RPS5
2
RPS5 [nucleoplasm]
(R-HSA-6791188)
RPS5 [cytosol]
(R-HSA-72379)
0.527
2
UniProt:Q9H9Z2 LIN28A
1
LIN28A [cytosol]
(R-HSA-500391)
0.527
2
UniProt:O60832 DKC1
1
DKC1 [nucleoplasm]
(R-HSA-163102)
0.527
2
UniProt:Q15696 ZRSR2
1
ZRSR2 [nucleoplasm]
(R-HSA-8865914)
0.527
3
UniProt:P62979 RPS27A
20
RPS27A(1-76) [endocytic vesicle membrane]
(R-HSA-939208)
RPS27A(77-156) [nucleoplasm]
(R-HSA-6798734)
Ub-33-RPS27A(1-76) [mitochondrial outer membrane]
(R-HSA-6783024)
Ub-63-RPS27A(1-76) [mitochondrial outer membrane]
(R-HSA-6783200)
Ub-6-RPS27A(1-76) [mitochondrial outer membrane]
(R-HSA-6783040)
Ub-11-RPS27A(1-76) [mitochondrial outer membrane]
(R-HSA-6783085)
Ub-48-RPS27A(1-76) [mitochondrial outer membrane]
(R-HSA-6783075)
Ub-29-RPS27A(1-76) [mitochondrial outer membrane]
(R-HSA-6783146)
Ub-27-RPS27A(1-76) [mitochondrial outer membrane]
(R-HSA-6783176)
N6-glycyl-L-lysine-RPS27A(1-76) [cytosol]
(R-HSA-8869045)
adenylatedlG76-RPS27A(1-76) [nucleoplasm]
(R-HSA-8852078)
RPS27A [cytosol]
(R-HSA-8853524)
adenylatedlG76-RPS27A(1-76) [cytosol]
(R-HSA-8852065)
Ub-48-RPS27A(1-76) [endoplasmic reticulum membrane]
(R-HSA-8943102)
Ub-48-RPS27A(1-76) [lysosomal membrane]
(R-HSA-9763033)
Ub-48-RPS27A(1-76) [endocytic vesicle membrane]
(R-HSA-9763012)
RPS27A(1-76) [endosome membrane]
(R-HSA-939238)
RPS27A(1-76) [plasma membrane]
(R-HSA-3149457)
Ub-29-RPS27A(1-76) [cytosol]
(R-HSA-5689223)
Ub-6-RPS27A(1-76) [cytosol]
(R-HSA-5689098)
0.527
2
UniProt:Q9H6F5 CCD86
0.527
2
UniProt:Q13601 KRR1
1
KRR1 [nucleoplasm]
(R-HSA-6790611)
0.527
3
IntAct:EBI-25589618 SSRNA
0.508
2
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