Maturation of spike protein

Stable Identifier
R-HSA-9683686
Type
Pathway
Species
Homo sapiens
Related Species
Human SARS coronavirus
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Maturation of spike protein
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Spike protein of SARS-Cov is subject to N-glycosylation and palmitoylation. The chaperone calnexin exclusively helps with protein folding. The end product is a homotrimer (Nal et al, 2005).

Literature References
PubMed ID Title Journal Year
15831954 Differential maturation and subcellular localization of severe acute respiratory syndrome coronavirus surface proteins S, M and E

Kam, J, Crescenzo-Chaigne, B, Escriou, N, Staropoli, I, Siu, L, Altmeyer, R, Chan, C, van der Werf, S, Yuen, KY, Chu, K, Kien, F, Tse, J, Nal, B

J. Gen. Virol. 2005
Participants
Events
Participates
as an event of
Event Information
Go Biological Process
viral protein processing (0019082)
Orthologous Events
Maturation of spike protein (Homo sapiens)
Disease
Name Identifier Synonyms
severe acute respiratory syndrome DOID:2945 SARS-CoV infection, SARS
Cross References
GlyCosmos
Authored
Stephan, R  (2020-04-08)
Reviewed
Acencio, ML  (2020-05-27)
Mazein, A  (2020-05-27)
Created
Stephan, R  (2020-04-17)
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