M protein gets N-glycosylated

Stable Identifier
R-HSA-9683751
Type
Reaction [uncertain]
Species
Homo sapiens
Related Species
Human SARS coronavirus
Compartment
endoplasmic reticulum lumen
ReviewStatus
5/5
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M protein gets N-glycosylated
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Protein M is exclusively N-glycosylated at asparagine 4 by an unknown glycosyltransferase. However, further processing of N-linked glycans is prevented in SARS-CoV-infected cells. Both the glycosylated and nonglycosylated M is incorporated into the virion. In summary, glycosylation of M is neither a prerequisite for intra-cellular transport nor for recruitment into the virion (Voss et al, 2006).
Literature References
PubMed ID Title Journal Year
16442106 Characterization of severe acute respiratory syndrome coronavirus membrane protein

Eickmann, M, Voss, D, Kern, A, Lanzavecchia, A, Becker, S, Traggiai, E, Stadler, K

FEBS Lett. 2006
Participants
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Output
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Orthologous Events
M protein gets N-glycosylated (Homo sapiens)
Disease
Name Identifier Synonyms
severe acute respiratory syndrome DOID:2945 SARS-CoV infection, SARS
Authored
Stephan, R  (2020-04-08)
Created
Stephan, R  (2020-04-17)
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