GalNAc is transferred onto 3a

Stable Identifier
R-HSA-9683760
Type
Reaction [transition]
Species
Homo sapiens
Related Species
Human SARS coronavirus
Compartment
endoplasmic reticulum-Golgi intermediate compartment
ReviewStatus
5/5
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GalNAc is transferred onto 3a
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A sialyltransferase adds a terminal sialic acid moiety to protein 3a with an O-linked glycosyl side chain. This glycosylated form later is associated with the virion (Oostra et al, 2006).
Literature References
PubMed ID Title Journal Year
16474139 Glycosylation of the severe acute respiratory syndrome coronavirus triple-spanning membrane proteins 3a and M

de Haan, CA, de Groot, RJ, Oostra, M, Rottier, PJ

J. Virol. 2006
Participants
Input
Output
Participates
as an event of
Catalyst Activity

polypeptide N-acetylgalactosaminyltransferase activity of GALNT1 [endoplasmic reticulum-Golgi intermediate compartment membrane]

Physical Entity
GALNT1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Homo sapiens)
Activity
polypeptide N-acetylgalactosaminyltransferase activity (GO:0004653)
Orthologous Events
GalNAc is transferred onto 3a (Homo sapiens)
Disease
Name Identifier Synonyms
severe acute respiratory syndrome DOID:2945 SARS-CoV infection, SARS
Authored
Stephan, R  (2020-04-08)
Created
Stephan, R  (2020-04-17)
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