Reactome | RHOD binds effectors at the Golgi membrane

RHOD binds effectors at the Golgi membrane

Stable Identifier

R-HSA-9693250

Type

Reaction [binding]

Species

Homo sapiens

Compartment

Golgi membrane, cytosol

ReviewStatus

5/5

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RHOD binds effectors at the Golgi membrane

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Active GTP bound RHOD binds the following effectors at the Golgi membrane:
FILIP1 (Gad et al. 2012)
WHAMM (Gad et al. 2012; Blom et al. 2015)

The following candidate effectors were reported to bind active RHOD by Bagci et al. 2020:
GOLGA8R (Bagci et al. 2020)
LMAN1 (Bagci et al. 2020)
VAPB (Bagci et al. 2020)

Literature References

PubMed ID	Title	Journal	Year
23087206	RhoD regulates cytoskeletal dynamics via the actin nucleation-promoting factor WASp homologue associated with actin Golgi membranes and microtubules Nehru, V, Ruusala, A, Gad, AK, Aspenström, P	Mol. Biol. Cell	2012
31871319	Mapping the proximity interaction network of the Rho-family GTPases reveals signalling pathways and regulatory mechanisms Tran, V, Gingras, AC, Elkholi, IE, Robert, A, Boulais, J, Faubert, D, Dubé, N, Hipfner, DR, Cote, JF, Lin, ZY, Bagci, H, Sriskandarajah, N, Thibault, MP	Nat. Cell Biol.	2020
25746724	RhoD is a Golgi component with a role in anterograde protein transport from the ER to the plasma membrane Nehru, V, Gad, AK, Blom, M, Reis, K, Blom, H, Aspenström, P	Exp. Cell Res.	2015