The amino acid sequence alignment of nsp14 and nsp16 from SARS-CoV-2 and of SARS-CoV-1 showed 95 and 93% of sequence identity respectively (Yoshimoto FK 2020). Structural studies suggest that properties and biological functions of SARS-CoV-2 nsp14 and nsp16 could be very similar to these of SARS-CoV-1 (Decroly E et al. 2011; Chen Y et al. 2011; Rosas-Lemus M et al. 2020; Lin S et al. 2020; Viswanathan T et al. 2020).
Taira, K, Shinobu, N, Yoneyama, M, Fujita, T, Miyagishi, M, Kikuchi, M, Imaizumi, T, Natsukawa, T
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