Ubiquination of protein E

Stable Identifier
R-HSA-9694529
Type
Reaction [uncertain]
Species
Homo sapiens
Related Species
Severe acute respiratory syndrome coronavirus 2
Compartment
endoplasmic reticulum lumen, endoplasmic reticulum membrane
ReviewStatus
5/5
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Ubiquination of protein E
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This COVID-19 event has been created by a combination of computational inference (see https://reactome.org/documentation/inferred-events) from SARS-CoV-1 data and manual curation, as described in the summation for the overall SARS-CoV-2 infection pathway.

Viral E protein is ubiquitinated both in vitro and in cells (Alvarez et al, 2011).
Literature References
PubMed ID Title Journal Year
20409569 The envelope protein of severe acute respiratory syndrome coronavirus interacts with the non-structural protein 3 and is ubiquitinated

Marcos-Villar, L, Jiménez-Guardeño, JM, DeDiego, ML, Enjuanes, L, Nieto-Torres, JL, Alvarez, E

Virology 2010
Participants
Input
Output
Participates
as an event of
Inferred From
Ubiquination of protein E (Homo sapiens)
Disease
Name Identifier Synonyms
COVID-19 DOID:0080600 2019 Novel Coronavirus (2019-nCoV), Wuhan seafood market pneumonia virus infection, 2019-nCoV infection, Wuhan coronavirus infection
Authored
Stephan, R  (2020-08-28)
Reviewed
Acencio, ML  (2020-09-09)
Created
Cook, J  (2020-07-07)
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