p-STAT5 binds the CDKN1A gene

Stable Identifier
R-HSA-9698041
Type
Reaction [binding]
Species
Homo sapiens
Compartment
nucleoplasm
ReviewStatus
5/5
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p-STAT5 binds the CDKN1A gene
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p-STAT5 binds to its cognate sites in the promoter of the CDKN1A gene in a FLT3-ITD-dependent manner as assessed by reporter assay and electrophoretic mobility shift assay (EMSA) (Takahashi et al, 2004).
Literature References
PubMed ID Title Journal Year
15003515 Flt3 mutation activates p21WAF1/CIP1 gene expression through the action of STAT5

Licht, JD, Harigae, H, Takahashi, S, Kaku, M, Sasaki, T

Biochem. Biophys. Res. Commun. 2004
Participants
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Output
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as an event of
Disease
Name Identifier Synonyms
cancer DOID:162 malignant tumor, malignant neoplasm, primary cancer
Authored
Rothfels, K  (2020-11-06)
Reviewed
Kazi, JU  (2020-11-06)
Created
Rothfels, K  (2020-08-21)
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