tandutinib-sensitive FLT3 mutants [plasma membrane]

Stable Identifier
R-HSA-9699540
Type
Set [DefinedSet]
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
Literature References
PubMed ID Title Journal Year
12124172 CT53518, a novel selective FLT3 antagonist for the treatment of acute myelogenous leukemia (AML)

Kelly, LM, Yu, JC, Boulton, CL, Apatira, M, Li, J, Sullivan, CM, Williams, I, Amaral, SM, Curley, DP, Duclos, N, Neuberg, D, Scarborough, RM, Pandey, A, Hollenbach, S, Abe, K, Lokker, NA, Gilliland, DG, Giese, NA

Cancer Cell 2002
15256420 Variable sensitivity of FLT3 activation loop mutations to the small molecule tyrosine kinase inhibitor MLN518

Clark, JJ, Cools, J, Curley, DP, Yu, JC, Lokker, NA, Giese, NA, Gilliland, DG

Blood 2004
22354205 Selective FLT3 inhibition of FLT3-ITD+ acute myeloid leukaemia resulting in secondary D835Y mutation: a model for emerging clinical resistance patterns

Moore, AS, Faisal, A, Gonzalez de Castro, D, Bavetsias, V, Sun, C, Atrash, B, Valenti, M, de Haven Brandon, A, Avery, S, Mair, D, Mirabella, F, Swansbury, J, Pearson, AD, Workman, P, Blagg, J, Raynaud, FI, Eccles, SA, Linardopoulos, S

Leukemia 2012
27132990 Metabolic alterations and drug sensitivity of tyrosine kinase inhibitor resistant leukemia cells with a FLT3/ITD mutation

Huang, A, Ju, HQ, Liu, K, Zhan, G, Liu, D, Wen, S, Garcia-Manero, G, Huang, P, Hu, Y

Cancer Lett. 2016
Participants
Participates
Disease
Name Identifier Synonyms
cancer DOID:162 malignant tumor, malignant neoplasm, primary cancer
Cite Us!