RANBP2(1-867)-ALK(1058-1620) fusion [cytosol]

Stable Identifier
R-HSA-9702002
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
E3 SUMO-protein ligase RanBP2 ecNumber evidence="29 31 33 37 44"2.3.2.-/ecNumber, RBP2_HUMAN
Locations in the PathwayBrowser
Expand all
Literature References
PubMed ID Title Journal Year
18701132 An inflammatory myofibroblastic tumor in liver with ALK and RANBP2 gene rearrangement: combination of distinct morphologic, immunohistochemical, and genetic features

Chen, ST, Lee, JC

Hum. Pathol. 2008
21164297 Epithelioid inflammatory myofibroblastic sarcoma: An aggressive intra-abdominal variant of inflammatory myofibroblastic tumor with nuclear membrane or perinuclear ALK

Mariño-Enríquez, A, Wang, WL, Roy, A, Lopez-Terrada, D, Lazar, AJ, Fletcher, CD, Coffin, CM, Hornick, JL

Am. J. Surg. Pathol. 2011
27874193 ALK oncoproteins in atypical inflammatory myofibroblastic tumours: novel RRBP1-ALK fusions in epithelioid inflammatory myofibroblastic sarcoma

Lee, JC, Li, CF, Huang, HY, Zhu, MJ, Mariño-Enríquez, A, Lee, CT, Ou, WB, Hornick, JL, Fletcher, JA

J. Pathol. 2017
External Reference Information
External Reference
UniProt:P49792 RANBP2
Gene Names
RANBP2, NUP358
Chain
chain:1-3224
Reference Genes
BioGPS Gene:5903 RANBP2
COSMIC (genes):RANBP2 RANBP2
CTD Gene:5903 RANBP2
dbSNP Gene:5903 RANBP2
ENSEMBL:ENSG00000153201 RANBP2
HGNC:9848 RANBP2
KEGG:hsa:5903 RANBP2
Monarch:5903 RANBP2
NCBI Entrez Gene:5903 RANBP2
OMIM:601181 RANBP2
UCSC:P49792 RANBP2
Reference Transcript
Other Identifiers
11722814_s_at
11722815_at
11722816_at
11754283_s_at
11758005_s_at
16884126
201711_PM_x_at
201711_x_at
201712_PM_s_at
201712_s_at
201713_PM_s_at
201713_s_at
226922_PM_at
226922_at
242712_PM_x_at
242712_x_at
2492220
2492221
2492223
2492290
2492297
2492298
2492302
2492303
2492304
2492305
2492307
2492308
2492309
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2499126
2499159
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2499642
2499643
2499644
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2499649
2499650
2499652
2563427
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2569095
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2570482
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2570503
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2570556
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2571326
2571327
2571328
2571329
2571331
2571332
2571333
2571335
3125190
32788_at
3748175
51177_at
5903
62295_at
8044161
8044263
8044304
8054414
8054532
8054557
8054676
82452_i_at
82453_r_at
A_14_P108565
A_14_P113906
A_23_P131664
A_24_P350890
A_33_P3272390
A_33_P3308740
D42063_at
GE61553
GE80234
GO:0000413
GO:0001678
GO:0001975
GO:0002224
GO:0002376
GO:0002753
GO:0003723
GO:0003755
GO:0003824
GO:0005096
GO:0005515
GO:0005634
GO:0005635
GO:0005642
GO:0005643
GO:0005654
GO:0005737
GO:0005829
GO:0006111
GO:0006457
GO:0006607
GO:0006886
GO:0006913
GO:0008270
GO:0015031
GO:0016020
GO:0016740
GO:0016853
GO:0016925
GO:0019209
GO:0019789
GO:0031267
GO:0031965
GO:0042405
GO:0044614
GO:0044615
GO:0044877
GO:0045824
GO:0046832
GO:0046872
GO:0046907
GO:0051028
GO:0051168
GO:0051642
GO:0061665
GO:0098772
GO:0106068
GO:0140096
GO:1990723
HMNXSV003021186
HMNXSV003037067
Hs.167822.0.S1_3p_at
Hs.199179.0.S1_3p_s_at
Hs.28248.0.A1_3p_at
ILMN_1654866
ILMN_1681811
ILMN_2320574
PH_hs_0011701
TC02000668.hg
TC02004500.hg
g6382078_3p_a_at
g924266_3p_a_at
Participates
as a candidate of
as a component of
Other forms of this molecule
RANBP2 [cytosol]
RANBP2(1-867)-p-7Y-ALK(1058-1620) fusion [cytosol]
RANBP2 [nuclear envelope]
monoSUMO1-K2592,K2650,K2723-RANBP2 [nuclear envelope]
polySUMO2-K2652,K2725-RANBP2 [nuclear envelope]
Modified Residues
Name
Insertion of residues 1058 to 1620 at 868 from UniProt:Q9UM73 ALK
Coordinate
868
Disease
Cross References
RefSeq
OpenTargets
ENSEMBL
Mondo
PRO
GlyGen
PDB
COSMIC
HPA
GeneCards
Pharos - Targets
Orphanet
HMDB Protein
Interactors (15)
Accession #Entities Entities Confidence Score Evidence (IntAct)
 UniProt:P62826 RAN  2 0.861 7
 UniProt:P63279 UBE2I  9 0.854 7
 UniProt:P46060 RANGAP1  3 0.713 5
 UniProt:O14524 NEMP1      0.643 4
 UniProt:P61769 B2M  11 0.643 5
 UniProt:Q9UBU9 NXF1  2 0.643 3
 UniProt:O60260 PRKN  4 0.639 11
 UniProt:Q921C5-1 BICD2      0.633 4
 UniProt:P52292 KPNA2  2 0.547 2
 UniProt:Q9BPX7 CG025      0.544 3
 UniProt:P12273 PIP  1 0.527 2
 UniProt:Q14974 KPNB1  5 0.527 2
 UniProt:Q5S007 LRRK2  1 0.527 3
 UniProt:P13569 CFTR  17 0.483 6
 UniProt:P04626 ERBB2  20 0.463 3
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