TFG(1-138)-p-7Y-ALK(1058-1620) fusion [cytosol]

Stable Identifier
R-HSA-9702019
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
Synonyms
Protein TFG, TFG_HUMAN, TFGs-ALK
Locations in the PathwayBrowser
Literature References
PubMed ID Title Journal Year
10556217 TRK-fused gene (TFG) is a new partner of ALK in anaplastic large cell lymphoma producing two structurally different TFG-ALK translocations

Falini, B, Delsol, G, Hernández, S, Rosenwald, A, Beà, S, Campo, E, Lamant, L, Hernández, L, Mason, DY, Pinyol, M, Ott, G, Pulford, K

Blood 1999
External Reference Information
External Reference
Gene Names
TFG
Chain
chain:1-400
Other Identifiers
10342
11715598_at
16943375
217839_PM_at
217839_at
2633774
2633775
2633776
2633777
2633779
2633780
2633781
2633782
2633784
2633787
2633789
2633791
2633798
2633802
2633805
2633806
2633807
2633809
8081316
88110_at
A_14_P136435
A_23_P29517
A_24_P345822
GE61614
GO:0005515
GO:0005737
GO:0005783
GO:0005829
GO:0006888
GO:0016192
GO:0023052
GO:0042802
GO:0043123
GO:0043226
GO:0043231
GO:0048208
GO:0061024
GO:0065003
GO:0070971
HMNXSV003004113
HMNXSV003056027
ILMN_1779213
ILMN_1812474
ILMN_2341815
PH_hs_0026111
TC03000512.hg
g5174718_3p_at
Participates
Other forms of this molecule
Modified Residues
Name
Insertion of residues 1058 to 1620 at 139 from UniProt:Q9UM73 ALK
Coordinate
139
Name
O4'-phospho-L-tyrosine at 1096
Coordinate
1096
PsiMod Name
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O4'-phospho-L-tyrosine at 1278
Coordinate
1278
PsiMod Name
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O4'-phospho-L-tyrosine at 1282
Coordinate
1282
PsiMod Name
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O4'-phospho-L-tyrosine at 1283
Coordinate
1283
PsiMod Name
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O4'-phospho-L-tyrosine at 1358
Coordinate
1358
PsiMod Name
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O4'-phospho-L-tyrosine at 1507
Coordinate
1507
PsiMod Name
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O4'-phospho-L-tyrosine at 1604
Coordinate
1604
PsiMod Name
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Disease
Name Identifier Synonyms
anaplastic large cell lymphoma DOID:0050744
cancer DOID:162 malignant tumor, malignant neoplasm, primary cancer
Interactors (11)
Accession #Entities Entities Confidence Score Evidence (IntAct)
 UniProt:Q9Y5V3 MAGED1  1 0.718 8
 UniProt:P13569 CFTR  17 0.707 7
 UniProt:Q8TDS5 OXER1  1 0.556 3
 UniProt:Q71SY5 MED25  1 0.556 3
 UniProt:P52597 HNRNPF  2 0.556 3
 UniProt:O14964 HGS  2 0.556 3
 UniProt:P42858 HTT  1 0.556 3
 UniProt:O75593 FOXH1  1 0.556 3
 UniProt:P62993 GRB2  1 0.547 2
 UniProt:P55735 SEC13  4 0.527 2
 UniProt:O94979 SEC31A  5 0.527 2
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