ATIC(1-229)-p-7Y ALK(1058-1620) fusion [cytosol]

Stable Identifier
R-HSA-9710847
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
Synonyms
Bifunctional purine biosynthesis protein ATIC, PUR9_HUMAN
Locations in the PathwayBrowser
Literature References
PubMed ID Title Journal Year
10702393 ATIC-ALK: A novel variant ALK gene fusion in anaplastic large cell lymphoma resulting from the recurrent cryptic chromosomal inversion, inv(2)(p23q35)

Colleoni, GW, Bridge, JA, Garicochea, B, Liu, J, Filippa, DA, Ladanyi, M

Am J Pathol 2000
External Reference Information
External Reference
Gene Names
ATIC, PURH, OK/SW-cl.86
Chain
initiator methionine:1, chain:1-592, chain:2-592
Reference Transcript
Other Identifiers
0000840301
11715755_a_at
16890490
208758_at
2526766
2526767
2526768
2526769
2526770
2526771
2526772
2526776
2526777
2526779
2526780
2526782
2526783
2526784
2526785
2526786
2526787
2526788
2526793
2526795
2526801
2526802
2526803
2526804
38811_at
471
8048120
A_23_P68087
D82348_at
GE57324
GO:0003360
GO:0003674
GO:0003824
GO:0003937
GO:0004643
GO:0005575
GO:0005576
GO:0005615
GO:0005622
GO:0005737
GO:0005829
GO:0005886
GO:0006139
GO:0006164
GO:0006189
GO:0008150
GO:0008152
GO:0009058
GO:0009116
GO:0009168
GO:0009259
GO:0010035
GO:0016020
GO:0016740
GO:0016787
GO:0016810
GO:0021549
GO:0021987
GO:0031100
GO:0034641
GO:0042803
GO:0043226
GO:0044281
GO:0045296
GO:0046452
GO:0046654
GO:0048856
GO:0070062
GO:0098761
HMNXSV003041780
ILMN_1673991
PH_hs_0005040
TC02001260.hg
TC02003807.hg
g2317691_3p_at
Participates
Other forms of this molecule
Modified Residues
Name
Insertion of residues 1058 to 1620 at 230 from UniProt:Q9UM73 ALK
Coordinate
230
Name
O4'-phospho-L-tyrosine at 1278
Coordinate
1278
PsiMod Name
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O4'-phospho-L-tyrosine at 1282
Coordinate
1282
PsiMod Name
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O4'-phospho-L-tyrosine at 1283
Coordinate
1283
PsiMod Name
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O4'-phospho-L-tyrosine at 1096
Coordinate
1096
PsiMod Name
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O4'-phospho-L-tyrosine at 1358
Coordinate
1358
PsiMod Name
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O4'-phospho-L-tyrosine at 1507
Coordinate
1507
PsiMod Name
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O4'-phospho-L-tyrosine at 1604
Coordinate
1604
PsiMod Name
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Disease
Cross References
RefSeq
OpenTargets
ZINC - Substances
ZINC - Biogenic
ZINC target
PRO
GlyGen
PDB
ZINC - Metabolites
GeneCards
Pharos - Targets
Orphanet
ZINC - Predictions - Purchasable
HMDB Protein
Interactors (1)
Accession #Entities Entities Confidence Score Evidence (IntAct)
 UniProt:P00533 EGFR  59 0.553 2
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