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ATIC(1-229)-p-7Y ALK(1058-1620) fusion dimer [cytosol]
Stable Identifier
R-HSA-9710872
Type
Complex
Species
Homo sapiens
Compartment
cytosol
Locations in the PathwayBrowser
Expand all
Disease (Homo sapiens)
Diseases of signal transduction by growth factor receptors and second messengers (Homo sapiens)
Signaling by ALK in cancer (Homo sapiens)
Signaling by ALK fusions and activated point mutants (Homo sapiens)
ALK fusion proteins bind PLCG1 (Homo sapiens)
GRB2- and PLC gamma-binding ALK fusion protein dimers [cytosol] (Homo sapiens)
ATIC(1-229)-p-7Y ALK(1058-1620) fusion dimer [cytosol] (Homo sapiens)
PLC gamma-binding ALK fusion proteins:PLCG1 [plasma membrane] (Homo sapiens)
GRB2- and PLC gamma-binding ALK fusion protein dimers [cytosol] (Homo sapiens)
ATIC(1-229)-p-7Y ALK(1058-1620) fusion dimer [cytosol] (Homo sapiens)
ALK fusions bind GRB2 (Homo sapiens)
ALK fusion dimers:GRB2 [cytosol] (Homo sapiens)
GRB2- and PLC gamma-binding ALK fusion protein dimers [cytosol] (Homo sapiens)
ATIC(1-229)-p-7Y ALK(1058-1620) fusion dimer [cytosol] (Homo sapiens)
GRB2- and PLC gamma-binding ALK fusion protein dimers [cytosol] (Homo sapiens)
ATIC(1-229)-p-7Y ALK(1058-1620) fusion dimer [cytosol] (Homo sapiens)
ALK fusions phosphorylate PLCG1 (Homo sapiens)
ALK fusions:p-4Y PLCG1 [plasma membrane] (Homo sapiens)
GRB2- and PLC gamma-binding ALK fusion protein dimers [cytosol] (Homo sapiens)
ATIC(1-229)-p-7Y ALK(1058-1620) fusion dimer [cytosol] (Homo sapiens)
GRB2- and PLC gamma-binding ALK fusion protein dimers [cytosol] (Homo sapiens)
ATIC(1-229)-p-7Y ALK(1058-1620) fusion dimer [cytosol] (Homo sapiens)
PLC gamma-binding ALK fusion proteins:PLCG1 [plasma membrane] (Homo sapiens)
GRB2- and PLC gamma-binding ALK fusion protein dimers [cytosol] (Homo sapiens)
ATIC(1-229)-p-7Y ALK(1058-1620) fusion dimer [cytosol] (Homo sapiens)
ALK mutants bind SHC (Homo sapiens)
ALK mutant dimers:SHC1 [cytosol] (Homo sapiens)
SHC-binding ALK mutant dimers [cytosol] (Homo sapiens)
ATIC(1-229)-p-7Y ALK(1058-1620) fusion dimer [cytosol] (Homo sapiens)
SHC-binding ALK mutant dimers [cytosol] (Homo sapiens)
ATIC(1-229)-p-7Y ALK(1058-1620) fusion dimer [cytosol] (Homo sapiens)
ALK mutants phosphorylate SHC1 (Homo sapiens)
ALK fusion dimers:p-3Y SHC1 [cytosol] (Homo sapiens)
SHC-binding ALK mutant dimers [cytosol] (Homo sapiens)
ATIC(1-229)-p-7Y ALK(1058-1620) fusion dimer [cytosol] (Homo sapiens)
ALK mutant dimers:SHC1 [cytosol] (Homo sapiens)
SHC-binding ALK mutant dimers [cytosol] (Homo sapiens)
ATIC(1-229)-p-7Y ALK(1058-1620) fusion dimer [cytosol] (Homo sapiens)
ALK mutants:p-3Y SHC binds GRB2 (Homo sapiens)
ALK fusion dimers:p-3Y SHC1 [cytosol] (Homo sapiens)
SHC-binding ALK mutant dimers [cytosol] (Homo sapiens)
ATIC(1-229)-p-7Y ALK(1058-1620) fusion dimer [cytosol] (Homo sapiens)
ALK fusion dimers:p-3Y SHC1:GRB2 [cytosol] (Homo sapiens)
SHC-binding ALK mutant dimers [cytosol] (Homo sapiens)
ATIC(1-229)-p-7Y ALK(1058-1620) fusion dimer [cytosol] (Homo sapiens)
Autophosphorylation of ALK fusions (Homo sapiens)
p-7Y ALK fusion protein dimers [cytosol] (Homo sapiens)
ATIC(1-229)-p-7Y ALK(1058-1620) fusion dimer [cytosol] (Homo sapiens)
Participants
components
x 2
ATIC(1-229)-p-7Y-ALK(1058-1620) fusion [cytosol]
(Homo sapiens)
Participates
as a candidate of
SHC-binding ALK mutant dimers [cytosol] (Homo sapiens)
GRB2- and PLC gamma-binding ALK fusion protein dimers [cytosol] (Homo sapiens)
p-7Y ALK fusion protein dimers [cytosol] (Homo sapiens)
Disease
Name
Identifier
Synonyms
anaplastic large cell lymphoma
DOID:0050744
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