DCTN1(1-599)-p-7Y-ALK(1058-1620) fusion [cytosol]

Stable Identifier
R-HSA-9711953
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
Dynactin subunit 1, DCTN1_HUMAN
Locations in the PathwayBrowser
Expand all
Literature References
PubMed ID Title Journal Year
22658521 Fusion of dynactin 1 to anaplastic lymphoma kinase in inflammatory myofibroblastic tumor

Oliveira, AM, Meyer, KJ, Wang, X, Oliveira, JL, Nguyen, EP, Erickson-Johnson, MR, Yi, ES, Maran, A, Yaszemski, MJ, Yang, P, Krishnan, C

Hum Pathol 2012
External Reference Information
External Reference
UniProt:Q14203 DCTN1
Gene Names
DCTN1
Chain
chain:1-1278
Reference Genes
ENSEMBL:ENSG00000204843 DCTN1
Participates
as a component of
Other forms of this molecule
DCTN1(1-1065)-ALK(1058-1620) fusion [cytosol]
DCTN1(1-599)-ALK(1058-1620) fusion [cytosol]
DCTN1(1-1177)-ALK(1058-1620) fusion [cytosol]
DCTN1(1-1065)-p-7Y-ALK(1058-1620) fusion [cytosol]
DCTN1(1-1177)-p-7Y-ALK(1058-1620) fusion [cytosol]
DCTN1 [cytosol]
Modified Residues
Name
Insertion of residues 1058 to 1620 at 600 from UniProt:Q9UM73 ALK
Coordinate
600
Name
O4'-phospho-L-tyrosine at 1096
Coordinate
1096
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O4'-phospho-L-tyrosine at 1278
Coordinate
1278
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O4'-phospho-L-tyrosine at 1282
Coordinate
1282
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O4'-phospho-L-tyrosine at 1283
Coordinate
1283
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O4'-phospho-L-tyrosine at 1358
Coordinate
1358
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O4'-phospho-L-tyrosine at 1507
Coordinate
1507
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O4'-phospho-L-tyrosine at 1604
Coordinate
1604
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Disease
Cross References
COSMIC
Interactors (31)
Accession #Entities Entities Confidence Score Evidence (IntAct)
 UniProt:Q15691 MAPRE1  1 0.9 9
 UniProt:Q13561 DCTN2  1 0.779 9
 UniProt:P30622-1 CLIP1      0.76 7
 UniProt:P47756 CAPZB  1 0.725 6
 UniProt:Q9UJW0 DCTN4  1 0.712 7
 UniProt:O00399 DCTN6  1 0.712 8
 UniProt:O75935 DCTN3  1 0.712 7
 UniProt:P61163 ACTR1A  1 0.712 7
 UniProt:Q9NZ32 ACTR10  4 0.712 7
 UniProt:P10636-8 MAPT  3 0.704 9
 UniProt:P42025 ACTR1B  4 0.65 6
 UniProt:P54256 HAP1      0.646 4
 UniProt:P52907 CAPZA1  2 0.638 3
 UniProt:Q96RK4 BBS4  1 0.635 3
 UniProt:Q14204 DYNC1H1  3 0.615 3
 UniProt:P13569 CFTR  17 0.615 10
 UniProt:P47755 CAPZA2  2 0.615 6
 UniProt:P30622 CLIP1  3 0.595 3
 UniProt:Q9Z0Y1  1 0.564 2
 UniProt:Q99KJ8  1 0.564 2
 UniProt:O08788  1 0.564 2
 UniProt:Q9NRI5 DISC1      0.553 2
 UniProt:Q9UNH7 SNX6      0.499 2
 UniProt:Q7Z460 CLASP1  1 0.483 3
 UniProt:O75122 CLASP2  1 0.483 2
 UniProt:Q13409 DYNC1I2  1 0.483 2
 UniProt:Q9BTE1 DCTN5  1 0.483 5
 UniProt:P43034 PAFAH1B1  1 0.48 2
 UniProt:Q6DN90 IQEC1      0.471 2
 UniProt:Q9JK25  1 0.463 2
 UniProt:Q8TCX1 DYNC2LI1  2 0.462 2
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