BCL11A(1-219)insDHPPA-p-7Y-ALK(1058-1620) fusion [cytosol]

Stable Identifier
R-HSA-9713447
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
fullName evidence="17"B-cell lymphoma/leukemia 11A, BC11A_HUMAN
Locations in the PathwayBrowser
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Literature References
PubMed ID Title Journal Year
28404650 Identification of a novel crizotinib-sensitive BCL11A-ALK gene fusion in a nonsmall cell lung cancer patient

Tian, Q, Deng, WJ, Li, ZW

Eur Respir J 2017
External Reference Information
External Reference
UniProt:Q9H165 BCL11A
Gene Names
BCL11A, CTIP1, EVI9, KIAA1809, ZNF856
Chain
chain:1-835
Reference Genes
BioGPS Gene:53335 BCL11A
COSMIC (genes):BCL11A BCL11A
CTD Gene:53335 BCL11A
dbSNP Gene:53335 BCL11A
ENSEMBL:ENSG00000119866 BCL11A
HGNC:13221 BCL11A
KEGG:hsa:53335 BCL11A
Monarch:53335 BCL11A
NCBI Gene:53335 BCL11A
OMIM:606557 BCL11A
UCSC:Q9H165 BCL11A
Reference Transcript
Participates
as a component of
Other forms of this molecule
BCL11A [nucleoplasm]
BCL11A(1-219)insDHPPA-ALK(1058-1620) fusion [cytosol]
Modified Residues
Name
Insertion of residues 1058 to 1620 at 220 from UniProt:Q9UM73 ALK
Coordinate
220
Name
Replacement of residues 219 to 219 by ADHPPA
Name
O4'-phospho-L-tyrosine at 1096
Coordinate
1096
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O4'-phospho-L-tyrosine at 1278
Coordinate
1278
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O4'-phospho-L-tyrosine at 1282
Coordinate
1282
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O4'-phospho-L-tyrosine at 1283
Coordinate
1283
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O4'-phospho-L-tyrosine at 1359
Coordinate
1359
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O4'-phospho-L-tyrosine at 1507
Coordinate
1507
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O4'-phospho-L-tyrosine at 1604
Coordinate
1604
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Disease
Name Identifier Synonyms
non-small cell lung carcinoma DOID:3908 Non-small cell lung cancer (disorder), NSCLC, NSCLC
Cross References
RefSeq
OpenTargets
ENSEMBL
Mondo
HPA
GeneCards
PRO
Pharos - Targets
GlyGen
PDB
Interactors (4)
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