PRKAR1A(1-183)-p-7Y ALK(1058-1620) fusion [cytosol]

Stable Identifier
R-HSA-9713476
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
Synonyms
cAMP-dependent protein kinase type I-alpha regulatory subunit, KAP0_HUMAN
PRKAR1A(1-183)-p-7Y ALK(1058-1620) fusion [cytosol] icon
Locations in the PathwayBrowser
Literature References
PubMed ID Title Journal Year
27245569 Comprehensive Genomic Profiling Identifies a Subset of Crizotinib-Responsive ALK-Rearranged Non-Small Cell Lung Cancer Not Detected by Fluorescence In Situ Hybridization

Ali, SM, Hensing, T, Schrock, AB, Allen, J, Sanford, E, Gowen, K, Kulkarni, A, He, J, Suh, JH, Lipson, D, Elvin, JA, Yelensky, R, Chalmers, Z, Chmielecki, J, Peled, N, Klempner, SJ, Firozvi, K, Frampton, GM, Molina, JR, Menon, S, Brahmer, JR, MacMahon, H, Nowak, J, Ou, SH, Zauderer, M, Ladanyi, M, Zakowski, M, Fischbach, N, Ross, JS, Stephens, PJ, Miller, VA, Wakelee, H, Ganesan, S, Salgia, R

Oncologist 2016
External Reference Information
External Reference
Gene Names
PRKAR1A, PKR1, PRKAR1, TSE1
Chain
chain:1-381
Other Identifiers
0001050072
11722007_a_at
11722008_a_at
11753791_s_at
16837326
200603_at
200604_s_at
200605_s_at
226_at
227_g_at
2346669
3732886
3732887
3732888
3732889
3732895
3732896
3732897
3732898
3732901
3732902
3732904
3732905
3732908
3732911
3732913
3732915
3732916
3732918
3732919
3732920
3732921
3732922
3732926
41768_at
54729_at
5573
60224_at
8009457
A_14_P136947
A_23_P433753
A_24_P245322
A_24_P356592
GE61216
GE87724
GO:0000003
GO:0000166
GO:0001707
GO:0001772
GO:0001932
GO:0002376
GO:0002862
GO:0003091
GO:0003674
GO:0004862
GO:0005515
GO:0005575
GO:0005622
GO:0005737
GO:0005768
GO:0005771
GO:0005813
GO:0005815
GO:0005829
GO:0005856
GO:0005886
GO:0005929
GO:0005930
GO:0005952
GO:0006357
GO:0006464
GO:0006469
GO:0006950
GO:0007010
GO:0007049
GO:0007143
GO:0007155
GO:0007165
GO:0007267
GO:0007268
GO:0007507
GO:0007596
GO:0008150
GO:0008283
GO:0008603
GO:0009058
GO:0009790
GO:0010738
GO:0016020
GO:0016301
GO:0016310
GO:0019899
GO:0019904
GO:0022607
GO:0030154
GO:0030234
GO:0030552
GO:0031410
GO:0031588
GO:0031594
GO:0031625
GO:0032991
GO:0034199
GO:0034236
GO:0034641
GO:0035556
GO:0040007
GO:0042592
GO:0043167
GO:0043226
GO:0043949
GO:0044853
GO:0045202
GO:0045214
GO:0045835
GO:0045859
GO:0046007
GO:0048646
GO:0048856
GO:0060038
GO:0071377
GO:0097224
GO:0097546
GO:0098978
GO:2000479
GO:2000480
HMNXSV003028511
HMNXSV003035036
Hs.183037.0.A3_3p_at
ILMN_1738632
ILMN_2277077
ILMN_2389590
M33336_at
TC17000804.hg
TC17002330.hg
TC17002331.hg
g1526988_3p_a_at
g4506062_3p_a_at
Participates
Other forms of this molecule
Modified Residues
Name
Insertion of residues 1058 to 1620 at 184 from UniProt:Q9UM73 ALK
Coordinate
184
Name
O4'-phospho-L-tyrosine at 1096
Coordinate
1096
PsiMod Name
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O4'-phospho-L-tyrosine at 1278
Coordinate
1278
PsiMod Name
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O4'-phospho-L-tyrosine at 1282
Coordinate
1282
PsiMod Name
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O4'-phospho-L-tyrosine at 1283
Coordinate
1283
PsiMod Name
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O4'-phospho-L-tyrosine at 1358
Coordinate
1358
PsiMod Name
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O4'-phospho-L-tyrosine at 1507
Coordinate
1507
PsiMod Name
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O4'-phospho-L-tyrosine at 1604
Coordinate
1604
PsiMod Name
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Disease
Name Identifier Synonyms
non-small cell lung carcinoma DOID:3908 Non-small cell lung cancer (disorder), NSCLC, NSCLC
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