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RAC2 translocates to the ER membrane
Stable Identifier
R-HSA-9714483
Type
Reaction [omitted]
Species
Homo sapiens
Compartment
plasma membrane
,
endoplasmic reticulum membrane
ReviewStatus
5/5
Locations in the PathwayBrowser
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Signal Transduction (Homo sapiens)
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Homo sapiens)
Signaling by Rho GTPases (Homo sapiens)
RHO GTPase cycle (Homo sapiens)
RAC2 GTPase cycle (Homo sapiens)
RAC2 translocates to the ER membrane (Homo sapiens)
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The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout
A portion of RAC2 is known to localize to the endoplasmic reticulum membrane (Michaelson et al. 2001).
Literature References
PubMed ID
Title
Journal
Year
11149925
Differential localization of Rho GTPases in live cells: regulation by hypervariable regions and RhoGDI binding
Silletti, J
,
Michaelson, D
,
Philips, MR
,
Rush, MG
,
D'Eustachio, P
,
Murphy, GA
J. Cell Biol.
2001
Participants
Input
RAC2:GTP [plasma membrane]
(Homo sapiens)
Output
RAC2:GTP [endoplasmic reticulum membrane]
(Homo sapiens)
Participates
as an event of
RAC2 GTPase cycle (Homo sapiens)
Orthologous Events
RAC2 translocates to the ER membrane (Bos taurus)
RAC2 translocates to the ER membrane (Caenorhabditis elegans)
RAC2 translocates to the ER membrane (Canis familiaris)
RAC2 translocates to the ER membrane (Danio rerio)
RAC2 translocates to the ER membrane (Dictyostelium discoideum)
RAC2 translocates to the ER membrane (Drosophila melanogaster)
RAC2 translocates to the ER membrane (Gallus gallus)
RAC2 translocates to the ER membrane (Mus musculus)
RAC2 translocates to the ER membrane (Rattus norvegicus)
RAC2 translocates to the ER membrane (Sus scrofa)
RAC2 translocates to the ER membrane (Xenopus tropicalis)
Authored
Rothfels, K (2020-07-14)
Orlic-Milacic, M (2020-07-14)
Reviewed
Fort, P (2021-02-05)
Created
Orlic-Milacic, M (2021-02-11)
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