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VAPB [Golgi membrane]
Stable Identifier
R-HSA-9715115
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
Golgi membrane
Synonyms
VAMP-associated protein B
Locations in the PathwayBrowser
Expand all
Signal Transduction (Homo sapiens)
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Homo sapiens)
Signaling by Rho GTPases (Homo sapiens)
RHO GTPase cycle (Homo sapiens)
RHOD GTPase cycle (Homo sapiens)
RHOD binds effectors at the Golgi membrane (Homo sapiens)
RHOD Golgi membrane effectors [Golgi membrane] (Homo sapiens)
VAPB [Golgi membrane] (Homo sapiens)
RHOD:GTP:RHOD Golgi membrane effectors [Golgi membrane] (Homo sapiens)
RHOD Golgi membrane effectors [Golgi membrane] (Homo sapiens)
VAPB [Golgi membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:O95292 VAPB
Gene Names
VAPB, UNQ484/PRO983
Chain
initiator methionine:, chain:2-243
Reference Genes
BioGPS Gene:9217 VAPB
COSMIC (genes):VAPB VAPB
CTD Gene:9217 VAPB
dbSNP Gene:9217 VAPB
ENSEMBL:ENSG00000124164 VAPB
ENSEMBL_homo_sapiens_GENE:ENSG00000124164.16 VAPB
HGNC:12649 VAPB
KEGG Gene (Homo sapiens):9217 VAPB
Monarch:9217 VAPB
NCBI Gene:9217 VAPB
OMIM:605704 VAPB
UCSC:O95292 VAPB
Reference Transcript
RefSeq:NM_004738.4 VAPB
RefSeq:NM_001195677.1 VAPB
Other Identifiers
11717583_s_at
11717584_a_at
11749369_a_at
11758066_s_at
16915231
202549_PM_at
202549_at
202550_PM_s_at
202550_s_at
225923_PM_at
225923_at
3890914
3890915
3890916
3890917
3890918
3890922
3890929
3890931
3890933
3890934
3890936
3890937
3890938
3890939
3890940
3890941
3890942
40940_at
41757_at
65637_at
8063620
9217
A_14_P121711
A_33_P3365586
GE54746
GE855235
GO:0005515
GO:0005737
GO:0005783
GO:0005789
GO:0005794
GO:0005886
GO:0006874
GO:0006888
GO:0006986
GO:0007029
GO:0008017
GO:0008092
GO:0016020
GO:0016192
GO:0019076
GO:0019899
GO:0023052
GO:0030301
GO:0030968
GO:0033149
GO:0036498
GO:0042803
GO:0043226
GO:0044790
GO:0044828
GO:0044829
GO:0044830
GO:0045070
GO:0045296
GO:0046725
GO:0046982
GO:0048487
GO:0055065
GO:0061024
GO:0061817
GO:0090114
GO:0090158
GO:0098542
HMNXSV003052877
Hs.159161.2.A1_3p_at
Hs.182625.0.S3_3p_at
ILMN_1678459
PH_hs_0010780
TC20000458.hg
TC20001316.hg
g4759301_3p_a_at
Participates
as a candidate of
RHOD Golgi membrane effectors [Golgi membrane] (Homo sapiens)
Other forms of this molecule
VAPB [endoplasmic reticulum membrane]
Inferred To
fan [Golgi membrane]
(Drosophila melanogaster)
VAPB [Golgi membrane]
(Bos taurus)
VAPB [Golgi membrane]
(Caenorhabditis elegans)
VAPB [Golgi membrane]
(Canis familiaris)
VAPB [Golgi membrane]
(Gallus gallus)
VAPB [Golgi membrane]
(Sus scrofa)
vapb [Golgi membrane]
(Xenopus tropicalis)
Vapb [Golgi membrane]
(Mus musculus)
Vapb [Golgi membrane]
(Rattus norvegicus)
Vap33 [Golgi membrane]
(Drosophila melanogaster)
osm-10 [Golgi membrane]
(Caenorhabditis elegans)
Homologues of VAPB [Golgi membrane]
(Caenorhabditis elegans)
Homologues of VAPB [Golgi membrane]
(Drosophila melanogaster)
Homologues of VAPB [Golgi membrane]
(Sus scrofa)
vpr-1 [Golgi membrane]
(Caenorhabditis elegans)
Cross References
RefSeq
NP_001182606.1
,
NP_004729.1
OpenTargets
ENSG00000124164
GeneCards
O95292
HPA
ENSG00000124164-VAPB
Ensembl
ENSP00000417175
,
ENSP00000379147
,
ENST00000395802
,
ENSG00000124164
,
ENST00000475243
PRO
O95292
Pharos - Targets
O95292
Orphanet
15704
PDB
3IKK
,
2MDK
Interactors (20)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P17612 PRKACA
4
PRKACA [mitochondrial matrix]
(R-HSA-9838291)
PRKACA [ciliary base]
(R-HSA-5610402)
PRKACA [nucleoplasm]
(R-HSA-111936)
PRKACA [cytosol]
(R-HSA-57844)
0.725
5
UniProt:P04626 ERBB2
20
ERBB2 G309E [plasma membrane]
(R-HSA-9665342)
ERBB2 G309A [plasma membrane]
(R-HSA-9665349)
ERBB2 S310F [plasma membrane]
(R-HSA-9665350)
ERBB2 S310Y [plasma membrane]
(R-HSA-9665344)
p-6Y-ERBB2 G309A [plasma membrane]
(R-HSA-9665381)
p-6Y-ERBB2 G309E [plasma membrane]
(R-HSA-9665382)
p-6Y-ERBB2 S310F [plasma membrane]
(R-HSA-9665379)
p-6Y-ERBB2 S310Y [plasma membrane]
(R-HSA-9665385)
p-Y-ERBB2 L755P [plasma membrane]
(R-HSA-9654268)
p-Y-ERBB2 I767M [plasma membrane]
(R-HSA-9654303)
p-Y-ERBB2 T798I [plasma membrane]
(R-HSA-9654618)
p-Y-ERBB2 Y772_A775dup [plasma membrane]
(R-HSA-9665652)
p-Y-ERBB2 T862A [plasma membrane]
(R-HSA-9654695)
p-Y-ERBB2 T798M [plasma membrane]
(R-HSA-9654615)
p-Y-ERBB2 H878Y [plasma membrane]
(R-HSA-9654833)
p-Y-ERBB2 V777L [plasma membrane]
(R-HSA-9654401)
p-Y-ERBB2 L755S [plasma membrane]
(R-HSA-9654194)
p-Y-ERBB2 V777E [plasma membrane]
(R-HSA-9654397)
p-Y-ERBB2 V777M [plasma membrane]
(R-HSA-9654398)
p-Y-ERBB2 L755M [plasma membrane]
(R-HSA-9654191)
0.671
4
UniProt:P22059 OSBP
1
OSBP [cytosol]
(R-HSA-429725)
0.643
6
UniProt:P13569 CFTR
17
PolyUb-CFTR [clathrin-coated endocytic vesicle membrane]
(R-HSA-8869104)
PolyUb-CFTR [plasma membrane]
(R-HSA-8867595)
CFTR [lysosomal membrane]
(R-HSA-5627279)
CFTR [Golgi-associated vesicle membrane]
(R-HSA-5627079)
CFTR [endosome membrane]
(R-HSA-6782965)
PolyUb-CFTR [endosome membrane]
(R-HSA-6782976)
CFTR F508del [endoplasmic reticulum membrane]
(R-HSA-8866834)
ub-CFTR F508del [cytosol]
(R-HSA-8866838)
ub-CFTR F508del [endoplasmic reticulum membrane]
(R-HSA-8866842)
CFTR G542* [plasma membrane]
(R-HSA-5678986)
CFTR G551D [plasma membrane]
(R-HSA-5678977)
CFTR W1282* [plasma membrane]
(R-HSA-5678976)
CFTR F508del [plasma membrane]
(R-HSA-5678978)
CFTR N1303K [plasma membrane]
(R-HSA-5678983)
CFTR [plasma membrane]
(R-HSA-383188)
CFTR [endoplasmic reticulum membrane]
(R-HSA-8866837)
misfolded CFTR [endoplasmic reticulum membrane]
(R-HSA-8868730)
0.64
12
UniProt:O95070 YIF1A
1
YIF1A [endoplasmic reticulum membrane]
(R-HSA-535599)
0.599
9
UniProt:Q7Z5P4 HSD17B13
1
HSD17B13 [cytosol]
(R-HSA-8862029)
0.556
3
UniProt:Q15125 EBP
1
EBP [endoplasmic reticulum membrane]
(R-HSA-195697)
0.556
3
UniProt:O00560 SDCBP
3
SDCBP [extracellular region]
(R-HSA-6806206)
SDCBP [azurophil granule lumen]
(R-HSA-6799372)
SDCBP [cytosol]
(R-HSA-373639)
0.556
3
UniProt:O00559 EBAG9
1
EBAG9 [Golgi membrane]
(R-HSA-9018507)
0.556
3
UniProt:O75380 NDUFS6
1
NDUFS6 [mitochondrial inner membrane]
(R-HSA-163922)
0.527
2
UniProt:Q9H2J7 SLC6A15
1
SLC6A15 [plasma membrane]
(R-HSA-352060)
0.527
3
UniProt:Q9BX63 BRIP1
2
p-S990,Ac-K1249-BRIP1 [nucleoplasm]
(R-HSA-5687710)
BRIP1 [cytosol]
(R-HSA-2564781)
0.527
3
UniProt:Q9UI09 NDUFA12
1
NDUFA12 [mitochondrial inner membrane]
(R-HSA-59864)
0.527
3
UniProt:Q13043 STK4
4
STK4(1-487) [cytosol]
(R-HSA-201627)
p-T183-STK4(1-326) [cytosol]
(R-HSA-2028682)
p-T183-STK4(1-487) [cytosol]
(R-HSA-2028258)
STK4(327-487) [cytosol]
(R-HSA-2028668)
0.527
4
UniProt:O95067 CCNB2
1
CCNB2 [cytosol]
(R-HSA-68897)
0.527
3
UniProt:O43181 NDUFS4
1
NDUFS4 [mitochondrial inner membrane]
(R-HSA-163946)
0.527
2
UniProt:Q9NZN5 ARHGEF12
1
ARHGEF12 [cytosol]
(R-HSA-416560)
0.527
4
UniProt:Q13188 STK3
4
p-T180-STK3(1-322) [cytosol]
(R-HSA-2028696)
STK3(323-491) [cytosol]
(R-HSA-2028684)
STK3(1-491) [cytosol]
(R-HSA-2028280)
p-T180-STK3(1-491) [cytosol]
(R-HSA-2028274)
0.527
4
UniProt:Q03137 Epha4
2
Epha4 [plasma membrane]
(R-MMU-3928415)
phospho-p-Y596,Y602-EPHA4 [plasma membrane]
(R-MMU-3928352)
0.499
2
UniProt:P27824 CANX
2
CANX [lumenal side of endoplasmic reticulum membrane]
(R-HSA-983091)
CANX [endoplasmic reticulum lumen]
(R-HSA-195906)
0.483
3
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