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FAM83B [cytosol]
Stable Identifier
R-HSA-9715184
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
fullName evidence="9"Protein FAM83B, FA83B_HUMAN
Locations in the PathwayBrowser
Expand all
Signal Transduction (Homo sapiens)
Signaling by Receptor Tyrosine Kinases (Homo sapiens)
Signaling by EGFR (Homo sapiens)
EGFR autophosphorylation (Homo sapiens)
EGFR:FAM83B,(FAM83A, FAM83D) [plasma membrane] (Homo sapiens)
FAM83B,(FAM83A, FAM83D) [cytosol] (Homo sapiens)
FAM83B [cytosol] (Homo sapiens)
FAM83B,(FAM83A, FAM83D) [cytosol] (Homo sapiens)
FAM83B [cytosol] (Homo sapiens)
FAM83B, (FAM83A, FAM83D) bind EGFR (Homo sapiens)
EGFR:FAM83B,(FAM83A, FAM83D) [plasma membrane] (Homo sapiens)
FAM83B,(FAM83A, FAM83D) [cytosol] (Homo sapiens)
FAM83B [cytosol] (Homo sapiens)
FAM83B,(FAM83A, FAM83D) [cytosol] (Homo sapiens)
FAM83B [cytosol] (Homo sapiens)
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Homo sapiens)
Signaling by Rho GTPases (Homo sapiens)
RHO GTPase cycle (Homo sapiens)
RND1 GTPase cycle (Homo sapiens)
RND1 binds effectors (Homo sapiens)
RND1 effectors [cytosol] (Homo sapiens)
FAM83B [cytosol] (Homo sapiens)
RND1:GTP:RND1 effectors [plasma membrane] (Homo sapiens)
RND1 effectors [cytosol] (Homo sapiens)
FAM83B [cytosol] (Homo sapiens)
RND2 GTPase cycle (Homo sapiens)
RND2 binds effectors (Homo sapiens)
RND2 effectors [cytosol] (Homo sapiens)
FAM83B [cytosol] (Homo sapiens)
RND2:GTP:RND2 effectors [plasma membrane] (Homo sapiens)
RND2 effectors [cytosol] (Homo sapiens)
FAM83B [cytosol] (Homo sapiens)
RND3 GTPase cycle (Homo sapiens)
RND3 binds effectors (Homo sapiens)
RND3 effectors [cytosol] (Homo sapiens)
FAM83B [cytosol] (Homo sapiens)
RND3:GTP:RND3 effectors [plasma membrane] (Homo sapiens)
RND3 effectors [cytosol] (Homo sapiens)
FAM83B [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q5T0W9 FAM83B
Gene Names
FAM83B, C6orf143
Chain
chain:1-1011
Reference Genes
BioGPS Gene:222584 FAM83B
COSMIC (genes):FAM83B FAM83B
CTD Gene:222584 FAM83B
dbSNP Gene:222584 FAM83B
ENSEMBL:ENSG00000168143 FAM83B
HGNC:21357 FAM83B
KEGG:hsa:222584 FAM83B
Monarch:222584 FAM83B
NCBI Gene:222584 FAM83B
UCSC:Q5T0W9 FAM83B
Reference Transcript
RefSeq:XM_017010478.1 FAM83B
RefSeq:XM_006715022.3 FAM83B
RefSeq:XM_011514395.2 FAM83B
RefSeq:NM_001010872.2 FAM83B
RefSeq:XM_011514394.2 FAM83B
Other Identifiers
11737162_at
1563900_PM_at
1563900_at
17009760
222584
232202_PM_at
232202_at
2910965
2910967
2910968
2910977
2910978
2910980
2910981
2910982
2910984
2910986
8120335
91391_r_at
A_24_P66780
A_32_P131347
GE748455
GO:0005154
GO:0005515
GO:0005737
GO:0005829
GO:0007165
GO:0008283
GO:0016020
GO:0019901
GO:0036312
GO:0036313
GO:0045742
HMNXSV003022034
HMNXSV003030072
Hs.152423.0.S1_3p_at
Hs2.381369.1.S1_3p_at
ILMN_1782863
PH_hs_0009171
PH_hs_0013551
TC06000675.hg
TC06002842.hg
Participates
as a candidate of
RND2 effectors [cytosol] (Homo sapiens)
RND3 effectors [cytosol] (Homo sapiens)
RND1 effectors [cytosol] (Homo sapiens)
as a member of
FAM83B,(FAM83A, FAM83D) [cytosol] (Homo sapiens)
Inferred To
FAM83B [cytosol]
(Bos taurus)
FAM83B [cytosol]
(Canis familiaris)
FAM83B [cytosol]
(Gallus gallus)
FAM83B [cytosol]
(Sus scrofa)
Fam83b [cytosol]
(Mus musculus)
Fam83b [cytosol]
(Rattus norvegicus)
fam83b [cytosol]
(Danio rerio)
fam83b [cytosol]
(Xenopus tropicalis)
Cross References
RefSeq
NP_001010872.1
,
XP_016865967.1
,
XP_011512697.1
,
XP_011512696.1
,
XP_006715085.1
OpenTargets
ENSG00000168143
ENSEMBL
ENSP00000304078
,
ENST00000306858
HPA
ENSG00000168143-FAM83B
PRO
Q5T0W9
Pharos - Targets
Q5T0W9
GlyGen
Q5T0W9
PDB
5QHN
,
5QHO
,
5LZK
,
5QHL
,
5QHM
,
5QHI
,
5QHS
,
5QHR
,
5QHK
,
5QHJ
,
5QHP
,
5QHQ
HMDB Protein
HMDBP13420
Interactors (7)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P48729 CSNK1A1
2
CSNK1A1 [cilium]
(R-HSA-5632507)
CSNK1A1 [cytosol]
(R-HSA-195263)
0.796
9
UniProt:P49674 CSNK1E
2
CSNK1E [cytosol]
(R-HSA-205877)
CSNK1E [nucleoplasm]
(R-HSA-421306)
0.643
5
UniProt:P31946 YWHAB
1
YWHAB [cytosol]
(R-HSA-48888)
0.615
4
UniProt:P48730 CSNK1D
3
CSNK1D [nucleoplasm]
(R-HSA-421305)
CSNK1D [endoplasmic reticulum-Golgi intermediate compartment membrane]
(R-HSA-5685717)
CSNK1D [cytosol]
(R-HSA-380315)
0.527
3
UniProt:Q7LC44 ARC
1
ARC [cytosol]
(R-HSA-9031622)
0.527
2
UniProt:P63104 YWHAZ
2
YWHAZ [cytosol]
(R-HSA-206099)
YWHAZ [nucleoplasm]
(R-HSA-450469)
0.483
2
UniProt:P62258 YWHAE
1
YWHAE [cytosol]
(R-HSA-194368)
0.483
3
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