RNF213(1-1172)-ALK(1058-1620) fusion [cytosol]

Stable Identifier
R-HSA-9715291
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
Synonyms
fullName evidence="34"E3 ubiquitin-protein ligase RNF213 ecNumber evidence="16"2.3.2.27/ecNumber ecNumber evidence="16"3.6.4.-/ecNumber, RN213_HUMAN
Locations in the PathwayBrowser
Literature References
PubMed ID Title Journal Year
12112524 Identification of novel fusion partners of ALK, the anaplastic lymphoma kinase, in anaplastic large-cell lymphoma and inflammatory myofibroblastic tumor

Marynen, P, De Wolf-Peeters, C, Pauwels, P, Somers, R, Hagemeijer, A, Pedeutour, F, Mentens, N, Cools, J, Maes, B, Wlodarska, I

Genes Chromosomes Cancer 2002
External Reference Information
External Reference
Gene Names
RNF213, ALO17, C17orf27, KIAA1554, KIAA1618, MYSTR
Chain
chain:1-5207
Other Identifiers
11731751_at
11731752_at
232155_PM_at
232155_at
241347_PM_at
241347_at
3737275
3737277
3737278
3737283
3737287
3737288
3737289
3737290
3737291
3737292
3737293
3737294
3737295
3737297
3737298
3737299
3737300
3737301
3737302
3737304
3737305
3737306
3737307
3737308
3737309
57674
68047_at
8010426
81774_at
A_33_P3219591
GE63147
GO:0000166
GO:0001525
GO:0002040
GO:0002376
GO:0003824
GO:0004842
GO:0005524
GO:0005634
GO:0005730
GO:0005737
GO:0005811
GO:0005829
GO:0006511
GO:0006629
GO:0006914
GO:0008152
GO:0016020
GO:0016567
GO:0016740
GO:0016787
GO:0016887
GO:0019216
GO:0023052
GO:0030163
GO:0036211
GO:0042742
GO:0043226
GO:0046872
GO:0048856
GO:0051865
GO:0061630
GO:0070534
GO:0098542
GO:0098792
GO:0120323
GO:0140042
GO:0140096
GO:0140657
GO:2000051
HMNXSV003000734
Hs.124135.0.S1_3p_at
ILMN_1674891
ILMN_1731203
ILMN_2289093
PH_hs_0040297
Participates
Other forms of this molecule
Modified Residues
Name
Insertion of residues 1058 to 1620 at 1173 from UniProt:Q9UM73 ALK
Coordinate
1173
Disease
Cross References
OpenTargets
GeneCards
PRO
Pharos - Targets
Orphanet
Interactors (7)
Accession #Entities Entities Confidence Score Evidence (IntAct)
 UniProt:P10321 HLA-C  8 0.564 2
 UniProt:P18031 PTPN1  2 0.527 2
 UniProt:P34741 SDC2  20 0.527 2
 UniProt:Q8N7X8 SIGL1      0.527 2
 UniProt:Q9UQV4 LAMP3      0.527 2
 UniProt:O60939 SCN2B  1 0.527 2
 UniProt:P05919 vpu  6 0.462 2
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