Phosphorylated RHOU translocates to the endosome membrane

Stable Identifier
R-HSA-9726862
Type
Reaction [omitted]
Species
Homo sapiens
Compartment
plasma membrane, endosome membrane
ReviewStatus
5/5
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Phosphorylated RHOU translocates to the endosome membrane
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RHOU phosphorylated at tyrosine residue Y254 by SRC translocates from the plasma membrane to the endosome membrane where it is found in an inactive, GDP-bound state (Alan et al. 2010).
Literature References
PubMed ID Title Journal Year
20547754 Regulation of the Rho family small GTPase Wrch-1/RhoU by C-terminal tyrosine phosphorylation requires Src

Graves, LM, Alan, JK, Cox, AD, Berzat, AC, Dewar, BJ

Mol Cell Biol 2010
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Orthologous Events
Phosphorylated RHOU translocates to the endosome membrane (Bos taurus)
Phosphorylated RHOU translocates to the endosome membrane (Caenorhabditis elegans)
Phosphorylated RHOU translocates to the endosome membrane (Canis familiaris)
Phosphorylated RHOU translocates to the endosome membrane (Danio rerio)
Phosphorylated RHOU translocates to the endosome membrane (Dictyostelium discoideum)
Phosphorylated RHOU translocates to the endosome membrane (Drosophila melanogaster)
Phosphorylated RHOU translocates to the endosome membrane (Gallus gallus)
Phosphorylated RHOU translocates to the endosome membrane (Mus musculus)
Phosphorylated RHOU translocates to the endosome membrane (Rattus norvegicus)
Phosphorylated RHOU translocates to the endosome membrane (Saccharomyces cerevisiae)
Phosphorylated RHOU translocates to the endosome membrane (Schizosaccharomyces pombe)
Phosphorylated RHOU translocates to the endosome membrane (Sus scrofa)
Phosphorylated RHOU translocates to the endosome membrane (Xenopus tropicalis)
Authored
Orlic-Milacic, M  (2021-04-13)
Reviewed
Shepelev, MV  (2021-03-30)
Created
Orlic-Milacic, M  (2021-04-13)
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