Reactome | HNRNPA1 [cytosol]

HNRNPA1 [cytosol]

Stable Identifier

R-HSA-9727902

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

hnRNP A1, heterogeneous nuclear ribonucleoprotein A1

Locations in the PathwayBrowser for interactor UniProt:P47756 CAPZB

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External Reference Information

External Reference

UniProt:P09651 HNRNPA1

Gene Names

HNRNPA1, HNRPA1

Chain

chain:1-372, initiator methionine:, chain:2-372

Reference Genes

COSMIC (genes):HNRNPA1 HNRNPA1

dbSNP Gene:3178 HNRNPA1

ENSEMBL:ENSG00000135486 HNRNPA1

Participates

as a component of

HNRNPA1:SUMO1-K62-p-S177-Ncap dimer [cytosol] (Homo sapiens)

as an input of

SARS-CoV-1 SUMO1-K62-p-S177-N dimer binds to HNRNPA1 (Homo sapiens)

Other forms of this molecule

HNRNPA1 [nucleoplasm]

Interactors (68)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q07666 KHDRBS1	3	p-Y435,Y440,Y443-KHDRBS1 [nucleoplasm] (R-HSA-8848970) p-Y435,Y440,Y443-KHDRBS1 [cytosol] (R-HSA-8848995) KHDRBS1 [nucleoplasm] (R-HSA-8848941)	0.875	10
UniProt:P07910 HNRNPC	3	HNRNPC [nucleoplasm] (R-HSA-71933) SUMO1-K250-HNRNPC [nucleoplasm] (R-HSA-4570543) HNRNPC [cytosol] (R-HSA-9715136)	0.792	5
UniProt:P31943 HNRNPH1	1	HNRNPH1 [nucleoplasm] (R-HSA-71941)	0.706	4
UniProt:P38159 RBMX	2	RBMX [cytosol] (R-HSA-9715135) RBMX [nucleoplasm] (R-HSA-71939)	0.706	4
UniProt:Q8IUH3 RBM45			0.672	6
UniProt:P35637 FUS	1	FUS [nucleoplasm] (R-HSA-72040)	0.671	5
UniProt:P22626 HNRNPA2B1	2	HNRNPA2B1 [nucleoplasm] (R-HSA-71929) HNRNPA2B1 [extracellular exosome] (R-HSA-8950304)	0.669	3
UniProt:P31942 HNRH3			0.659	3
UniProt:P0DTC9 N	13	SUMO1-K62-ADPr-p-11S,2T-metR95,177-N [cytosol] (R-COV-9729340) SUMO1-K62-ADPr-p-11S,2T-metR95,177-N [endoplasmic reticulum-Golgi intermediate compartment membrane] (R-COV-9729341) ADPr-p-11S,2T-metR95,177-N [cytosol] (R-COV-9729275) p-11S,2T-metR95,177-N [cytosol] (R-COV-9729308) p-11S,2T-N [cytosol] (R-COV-9729264) p-8S,2T-N [cytosol] (R-COV-9729277) p-8S-N [cytosol] (R-COV-9729335) p-S188,206-N [cytosol] (R-COV-9729324) N [cytosol] (R-COV-9694300) SUMO1-K62,ADPr-,p-11S,2T,met-R95,177,Ac-K375-N [cytosol] (R-COV-9756489) N [plasma membrane] (R-COV-9694356) SUMO1-K62-ADPr-p-11S,2T-metR95,177-N [nucleolus] (R-COV-9729339) SUMO1-K62-ADPr-p-11S,2T-metR95,177-N [plasma membrane] (R-COV-9729325)	0.643	4
UniProt:P38919 EIF4A3	2	EIF4A3 [nucleoplasm] (R-HSA-8849149) EIF4A3 [cytosol] (R-HSA-927868)	0.643	3
UniProt:Q96PK6 RBM14	1	RBM14 [nucleoplasm] (R-HSA-8938345)	0.615	3
UniProt:Q9NZB2 F120A			0.615	3
UniProt:P23246 SFPQ	3	SFPQ [nucleoplasm] (R-HSA-3900138) p-Y-SFPQ [nucleoplasm] (R-HSA-8849461) SFPQ [cytosol] (R-HSA-9635505)	0.615	3
UniProt:P14866 HNRNPL	1	HNRNPL [nucleoplasm] (R-HSA-71947)	0.615	3
UniProt:P59595 N	9	N [cytosol] (R-COV-9683625) p-S177-N [cytosol] (R-COV-9683754) ADPr-p-S177-N [cytosol] (R-COV-9686058) SUMO1-K62-ADPr-p-S177-N [cytosol] (R-COV-9682916) SUMO1-K62-ADPr-p-S177-N [viral capsid] (R-COV-9685478) SUMO1-K62-ADPr-p-S177-N [endoplasmic reticulum-Golgi intermediate compartment membrane] (R-COV-9683641) N [plasma membrane] (R-COV-9683611) SUMO1-K62-ADPr-p-S177-N [nucleolus] (R-COV-9683730) SUMO1-K62-ADPr-p-S177-N [plasma membrane] (R-COV-9686063)	0.602	3
UniProt:P27958-PRO_0000037577			0.599	4
UniProt:Q5BKZ1 ZN326			0.597	4
UniProt:P11387 TOP1	2	TOP1 [nucleoplasm] (R-HSA-4641363) monoSUMO1-K117-TOP1 [nucleoplasm] (R-HSA-4641364)	0.597	4
UniProt:P51991 HNRNPA3	1	HNRNPA3 [nucleoplasm] (R-HSA-71931)	0.564	2
UniProt:Q9NR30 DDX21	1	DDX21 [nucleoplasm] (R-HSA-5250652)	0.564	2
UniProt:Q8NC51 SERB1			0.548	4
UniProt:P09651 HNRNPA1	2	HNRNPA1 [nucleoplasm] (R-HSA-71927) HNRNPA1 [cytosol] (R-HSA-9727902)	0.536	2
UniProt:P63104 YWHAZ	2	YWHAZ [cytosol] (R-HSA-206099) YWHAZ [nucleoplasm] (R-HSA-450469)	0.536	2
UniProt:Q12906 ILF3	3	ILF3 [nucleoplasm] (R-HSA-9760401) ILF3 [cytosol] (R-HSA-450564) p-T188,T315-ILF3 [cytosol] (R-HSA-9836381)	0.527	2
UniProt:O75319 DUS11			0.527	2
UniProt:P43243 MATR3			0.527	2
UniProt:Q08211 DHX9	3	DHX9 [nucleoplasm] (R-HSA-53517) DHX9 [cytosol] (R-HSA-847700) p-DHX9 [cytosol] (R-HSA-9836168)	0.527	2
UniProt:Q09161 NCBP1	2	NCBP1 [nucleoplasm] (R-HSA-51469) NCBP1 [cytosol] (R-HSA-162459)	0.527	3
UniProt:Q9Y5S9 RBM8A	2	RBM8A [cytosol] (R-HSA-162462) RBM8A [nucleoplasm] (R-HSA-156659)	0.527	2
UniProt:Q9UHD9 UBQLN2	1	UBQLN2 [cytosol] (R-HSA-8866007)	0.524	2
UniProt:Q8IZH2 XRN1	1	XRN1 [cytosol] (R-HSA-429835)	0.519	2
UniProt:Q14141 SEPT6			0.499	3
UniProt:Q32P51 RA1L2			0.499	2
UniProt:Q14151 SAFB2			0.483	2
UniProt:Q15717 ELAVL1	6	ELAVL1 [nucleoplasm] (R-HSA-450601) p-S158,S221-ELAVL1 [nucleoplasm] (R-HSA-450576) p-S221,S318-ELAVL1 [nucleoplasm] (R-HSA-450532) ELAVL1 [cytosol] (R-HSA-450582) p-S221,S318-ELAVL1 [cytosol] (R-HSA-450448) p-S158,S221-ELAVL1 [cytosol] (R-HSA-450376)	0.483	2
UniProt:Q15233 NONO			0.483	3
UniProt:Q13573 SNW1	1	SNW1 [nucleoplasm] (R-HSA-351663)	0.483	2
UniProt:P17844 DDX5	4	DDX5 [nucleoplasm] (R-HSA-3900136) DDX5 [cytosol] (R-HSA-9682643) polySUMO2-K53-DDX5 [nucleoplasm] (R-HSA-3900186) monoSUMO1-K53-DDX5 [nucleoplasm] (R-HSA-3900041)	0.483	2
UniProt:Q13151 HNRNPA0	1	HNRNPA0 [nucleoplasm] (R-HSA-71925)	0.483	2
UniProt:P13569 CFTR	17	misfolded CFTR [endoplasmic reticulum membrane] (R-HSA-8868730) CFTR [endoplasmic reticulum membrane] (R-HSA-8866837) CFTR [plasma membrane] (R-HSA-383188) CFTR N1303K [plasma membrane] (R-HSA-5678983) CFTR F508del [plasma membrane] (R-HSA-5678978) CFTR W1282* [plasma membrane] (R-HSA-5678976) CFTR G551D [plasma membrane] (R-HSA-5678977) CFTR G542* [plasma membrane] (R-HSA-5678986) ub-CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866842) ub-CFTR F508del [cytosol] (R-HSA-8866838) CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866834) PolyUb-CFTR [endosome membrane] (R-HSA-6782976) CFTR [endosome membrane] (R-HSA-6782965) CFTR [Golgi-associated vesicle membrane] (R-HSA-5627079) CFTR [lysosomal membrane] (R-HSA-5627279) PolyUb-CFTR [plasma membrane] (R-HSA-8867595) PolyUb-CFTR [clathrin-coated endocytic vesicle membrane] (R-HSA-8869104)	0.483	10
UniProt:Q96I24 FUBP3			0.483	2
UniProt:Q7L2J0 MEPCE			0.483	2
UniProt:Q6UN15 FIP1L1	9	FIP1L1 [nucleoplasm] (R-HSA-6805150) FIP1L1(1-339)-PDGFRA(580-1089) fusion [cytosol] (R-HSA-9672499) FIP1L1(1-272)-PDGFRA(567-1089) fusion [cytosol] (R-HSA-9672496) FIP1L1(1-391)insAQCP-PDGFRA(577-1089) fusion [cytosol] (R-HSA-9672502) FIP1L1(1-392)insDCY-PDGFRA(585-1089) fusion [cytosol] (R-HSA-9672506) p-11Y-FIP1L1(1-339)-PDGFRA(580-1089) fusion [cytosol] (R-HSA-9673872) p-11Y-FIP1L1(1-392)insDCY-PDGFRA(585-1089) fusion [cytosol] (R-HSA-9673621) p-11Y-FIP1L1(1-391)insAQCP-PDGFRA(577-1089) fusion [cytosol] (R-HSA-9673879) p-11Y-FIP1L1(1-272)-PDGFRA(567-1069) fusion [cytosol] (R-HSA-9673867)	0.483	2
UniProt:O43823 AKAP8			0.483	2
UniProt:P47756 CAPZB	1	CAPZB [cytosol] (R-HSA-879409)	0.483	2
UniProt:Q8IX01 SUGP2			0.483	2
UniProt:P26196 DDX6	1	DDX6 [cytosol] (R-HSA-430032)	0.483	2
UniProt:Q86VM9 ZCH18			0.483	2
UniProt:Q14966 ZNF638	1	ZNF638 [nucleoplasm] (R-HSA-8939429)	0.483	2
UniProt:Q12905 ILF2	5	ILF2 [cytosol] (R-HSA-9836392) ILF2 [specific granule lumen] (R-HSA-6799611) ILF2 [extracellular region] (R-HSA-6799684) ILF2 [tertiary granule lumen] (R-HSA-6800995) ILF2 [ficolin-1-rich granule lumen] (R-HSA-6801001)	0.483	2
UniProt:P55265 ADAR	2	ADAR1 [cytosol] (R-HSA-9835955) ADAR [nucleoplasm] (R-HSA-53939)	0.483	2
UniProt:P62316 SNRPD2	2	SNRPD2 [cytosol] (R-HSA-191810) SNRPD2 [nucleoplasm] (R-HSA-71901)	0.483	2
UniProt:O95758 PTBP3			0.483	2
UniProt:Q96KR1 ZFR			0.483	2
UniProt:P78332 RBM6			0.483	2
UniProt:P55795 HNRNPH2	1	HNRNPH2 [nucleoplasm] (R-HSA-71943)	0.483	2
UniProt:Q13285 NR5A1	3	NR5A1 [nucleoplasm] (R-HSA-452955) polySUMO2-K119,K194-NR5A1 [nucleoplasm] (R-HSA-4546383) monoSUMO1-K119,K194-NR5A1 [nucleoplasm] (R-HSA-4546382)	0.483	2
UniProt:Q9UKV3 ACIN1	4	ACIN1 [cytosol] (R-HSA-212519) ACIN1(1094-1341) [cytosol] (R-HSA-212516) ACIN1(1-1093) [cytosol] (R-HSA-212520) ACIN1 [nucleoplasm] (R-HSA-9770238)	0.483	2
UniProt:Q9HCK8 CHD8	1	CHD8 [nucleoplasm] (R-HSA-3221598)	0.483	2
UniProt:Q9BXP5 SRRT	1	SRRT [nucleoplasm] (R-HSA-6814858)	0.483	2
UniProt:Q9UKV8 AGO2	2	AGO2 [cytosol] (R-HSA-209723) AGO2 [nucleoplasm] (R-HSA-5578701)	0.483	2
UniProt:Q9H0D6 XRN2	2	XRN2 [nucleoplasm] (R-HSA-6791205) XRN2 [cytosol] (R-HSA-391297)	0.483	2
UniProt:Q15424 SAFB	3	monoSUMO1-K231,K294-SAFB [nucleoplasm] (R-HSA-4085343) polySUMO2,3-K231,K294-SAFB [nucleoplasm] (R-HSA-4085357) SAFB [nucleoplasm] (R-HSA-4085379)	0.483	2
UniProt:Q16630 CPSF6	2	CPSF6(1-490)-FGFR1(429-822) fusion [cytosol] (R-HSA-1614368) CPSF6(1-490)-p-FGFR1(429-822) fusion [cytosol] (R-HSA-1838987)	0.483	2
UniProt:Q14498 RBM39	1	RBM39 [nucleoplasm] (R-HSA-9770254)	0.483	2
IntAct:EBI-6857440 NS3			0.462	2
UniProt:O60477 BRNP1			0.462	2
UniProt:P03372 ESR1	10	ESR1 [cytosol] (R-HSA-9020968) ESR1 [nucleoplasm] (R-HSA-446168) Me260-PalmS-ESR1 [plasma membrane] (R-HSA-9637788) PalmS-ESR1 [plasma membrane] (R-HSA-9021057) PalmS-ESR1 [cytosol] (R-HSA-9020974) Me260-ESR1 [cytosol] (R-HSA-9632177) p-S167-ESR1 [cytosol] (R-HSA-9841254) p-S167-ESR1 [nucleoplasm] (R-HSA-9841867) monoSUMO1-5K-ESR1 [nucleoplasm] (R-HSA-4090302) p-S118-ESR1 [nucleoplasm] (R-HSA-9024210)	0.462	2

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