Reactome | UVRAG [endoplasmic reticulum-Golgi intermediate compartment membrane]

UVRAG [endoplasmic reticulum-Golgi intermediate compartment membrane]

Stable Identifier

R-HSA-9730510

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

endoplasmic reticulum-Golgi intermediate compartment membrane

Synonyms

UV radiation resistance-associated gene protein, UVRAG_HUMAN, Vps38

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q9P2Y5 UVRAG

Gene Names

UVRAG

Chain

chain:1-699

Reference Genes

BioGPS Gene:7405 UVRAG

COSMIC (genes):UVRAG UVRAG

CTD Gene:7405 UVRAG

dbSNP Gene:7405 UVRAG

ENSEMBL:ENSG00000198382 UVRAG

ENSEMBL_homo_sapiens_GENE:ENSG00000198382.9 UVRAG

HGNC:12640 UVRAG

KEGG Gene (Homo sapiens):7405 UVRAG

Monarch:7405 UVRAG

NCBI Gene:7405 UVRAG

OMIM:602493 UVRAG

UCSC:Q9P2Y5 UVRAG

Reference Transcript

RefSeq:NM_003369.3 UVRAG

Other Identifiers

11719036_at

11719037_a_at

11745991_a_at

11750401_a_at

16729188

203241_PM_at

203241_at

3340698

3340699

3340704

3340707

3340710

3340711

3340713

3340717

3340725

3340728

3340729

3340733

3340736

3340738

3340743

3340747

3340764

3340783

3340802

3340803

3340804

3340805

3340806

3340816

39429_at

7405

7942626

A_14_P113524

A_23_P33482

A_33_P3260722

GE79363

GO:0000149

GO:0000323

GO:0000421

GO:0000775

GO:0000910

GO:0005515

GO:0005634

GO:0005694

GO:0005737

GO:0005764

GO:0005768

GO:0005769

GO:0005770

GO:0005773

GO:0005776

GO:0005783

GO:0005813

GO:0005815

GO:0005856

GO:0006281

GO:0006629

GO:0006890

GO:0006914

GO:0006974

GO:0007010

GO:0007051

GO:0007059

GO:0007098

GO:0010506

GO:0016192

GO:0017124

GO:0030496

GO:0031410

GO:0032465

GO:0032801

GO:0032991

GO:0033116

GO:0035032

GO:0035493

GO:0036092

GO:0036211

GO:0043226

GO:0045335

GO:0046718

GO:0051684

GO:0061024

GO:0065003

GO:0070418

GO:0071900

GO:0071985

GO:0097352

GO:0097680

GO:0110165

GO:1901098

HMNXSV003010312

HMNXSV003057077

ILMN_1761069

ILMN_1909466

PH_hs_0001261

TC11000814.hg

X99050_rna1_at

g4507860_3p_at

Participates

as a component of

UVRAG:O-glycosyl 3a tetramer [endoplasmic reticulum-Golgi intermediate compartment membrane] (Homo sapiens)

as an input of

SARS-CoV-2 3a binds to UVRAG (Homo sapiens)

Other forms of this molecule

UVRAG [cytosol]

Cross References

RefSeq

NP_003360.2

OpenTargets

ENSG00000198382

HPA

ENSG00000198382-UVRAG

GeneCards

Q9P2Y5

Ensembl

ENSP00000431256, ENST00000356136, ENST00000533454, ENSP00000434082, ENSP00000348455, ENSP00000436270, ENST00000532130, ENST00000531818, ENSG00000198382

PRO

Q9P2Y5

Pharos - Targets

Q9P2Y5

PDB

7BL1

Interactors (17)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q14457 BECN1	4	K63polyUb-BECN1 [cytosol] (R-HSA-6782989) ISG15-K-BECN1 [cytosol] (R-HSA-9853030) p-S15-BECN1 [cytosol] (R-HSA-5682391) BECN1 [cytosol] (R-HSA-1632841)	0.97	45
UniProt:Q8NEB9 PIK3C3	2	PIK3C3 [phagocytic vesicle membrane] (R-HSA-6798182) PIK3C3 [cytosol] (R-HSA-188011)	0.929	23
UniProt:Q92622 RUBIC			0.81	9
UniProt:Q99570 PIK3R4	2	PIK3R4 [phagocytic vesicle membrane] (R-HSA-6798171) PIK3R4 [cytosol] (R-HSA-188010)	0.669	5
UniProt:Q6NUQ1 RINT1	1	RINT1 [cytosol] (R-HSA-6810991)	0.669	18
UniProt:P46937 YAP1	7	p-S127-YAP1 [cytosol] (R-HSA-2028553) p-5S-YAP1 [cytosol] (R-HSA-2028554) p-Y407-YAP1 [nucleoplasm] (R-HSA-8956661) p-Y-YAP1 [cytosol] (R-HSA-8937843) p-Y-YAP1 [nucleoplasm] (R-HSA-8937857) YAP1 [cytosol] (R-HSA-1253345) YAP1 [nucleoplasm] (R-HSA-1253322)	0.623	2
UniProt:P46934 NEDD4	1	NEDD4 [cytosol] (R-HSA-975992)	0.623	2
UniProt:Q9Y371 SHLB1			0.623	11
UniProt:Q07812 BAX	3	BAX [cytosol] (R-HSA-139916) BAX activated [cytosol] (R-HSA-139907) BAX [mitochondrial outer membrane] (R-HSA-139949)	0.612	6
UniProt:P0DTC3 3a	9	O-glycosyl 3a [virion membrane] (R-COV-9694395) O-glycosyl 3a [endocytic vesicle membrane] (R-COV-9694729) O-glycosyl 3a [endoplasmic reticulum-Golgi intermediate compartment membrane] (R-COV-9694386) GalNAc-O-3a [endoplasmic reticulum-Golgi intermediate compartment] (R-COV-9694658) 3a [endoplasmic reticulum-Golgi intermediate compartment] (R-COV-9694716) 3a [endoplasmic reticulum lumen] (R-COV-9694584) O-glycosyl 3a [endolysosome membrane] (R-COV-9754541) O-glycosyl 3a [plasma membrane] (R-COV-9694433) O-glycosyl 3a [extracellular region] (R-COV-9694387)	0.602	6
UniProt:Q96AX1 VPS33A	1	VPS33A [endosome membrane] (R-HSA-2197804)	0.564	4
UniProt:Q9QUM4 SLAF1			0.558	6
UniProt:P61981 YWHAG	1	YWHAG [cytosol] (R-HSA-380312)	0.527	2
UniProt:Q04917 YWHAH	1	YWHAH [cytosol] (R-HSA-1445107)	0.527	2
UniProt:P35606 COPB2	4	COPB2 [endoplasmic reticulum membrane] (R-HSA-6810957) COPB2 [transport vesicle] (R-HSA-6808741) COPB2 [cytosol] (R-HSA-199972) COPB2 [Golgi membrane] (R-HSA-6808739)	0.462	6
UniProt:O43264 ZW10	1	ZW10 [cytosol] (R-HSA-377880)	0.462	12
UniProt:A2RRP1 NBAS	1	NBAS [cytosol] (R-HSA-6810973)	0.462	9

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