Reactome | p-IRAK2:K63-linked pUb oligo-TRAF6 [endosome membrane]

p-IRAK2:K63-linked pUb oligo-TRAF6 [endosome membrane]

Stable Identifier

R-HSA-975164

Type

Complex

Species

Homo sapiens

Compartment

endosome membrane

Locations in the PathwayBrowser

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Participants

components

Participates

as an input of

SARS-CoV-1 nsp3 deubiquinates K63-linked pUb oligo-TRAF6 (TLR7/8 signaling) (Homo sapiens)
Activated TRAF6:p-IRAK2 interacts with TAK1 complex upon TLR7/8 or 9 stimulation (Homo sapiens)

as a component of

p-IRAK2:K63-linked pUb oligo-TRAF6:free K63-linked pUb:p-TAK1complex [endosome membrane] (Homo sapiens)
p-IRAK2:K63-linked pUb oligo-TRAF6:free K63 pUb:TAK1 complex [endosome membrane] (Homo sapiens)

as an output of

Auto ubiquitination of oligo-TRAF6 bound to p-IRAK2 at endosome membrane (Homo sapiens)

as a member of

K63-linked polyUb TRAF6 complexes [endosome membrane] (Homo sapiens)

Inferred To

p-IRAK2:K63-linked pUb oligo-TRAF6 [endosome membrane] (Bos taurus)

p-IRAK2:K63-linked pUb oligo-TRAF6 [endosome membrane] (Canis familiaris)

p-IRAK2:K63-linked pUb oligo-TRAF6 [endosome membrane] (Drosophila melanogaster)

p-IRAK2:K63-linked pUb oligo-TRAF6 [endosome membrane] (Gallus gallus)

p-IRAK2:K63-linked pUb oligo-TRAF6 [endosome membrane] (Mus musculus)

p-IRAK2:K63-linked pUb oligo-TRAF6 [endosome membrane] (Rattus norvegicus)

p-IRAK2:K63-linked pUb oligo-TRAF6 [endosome membrane] (Sus scrofa)

p-IRAK2:K63-linked pUb oligo-TRAF6 [endosome membrane] (Xenopus tropicalis)

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