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KCNJ5 [plasma membrane]
Stable Identifier
R-HSA-975373
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
G protein-activated inward rectifier potassium channel 4, IRK5_HUMAN
Locations in the PathwayBrowser
Expand all
Neuronal System (Homo sapiens)
Potassium Channels (Homo sapiens)
Inwardly rectifying K+ channels (Homo sapiens)
G protein gated Potassium channels (Homo sapiens)
Activation of G protein gated Potassium channels (Homo sapiens)
Activation of GIRK/Kir3 Channels (Homo sapiens)
GABA B receptor G-protein beta-gamma and Kir3 channel complex [plasma membrane] (Homo sapiens)
Kir heterotetramers [plasma membrane] (Homo sapiens)
Kir3 heterotetramer [plasma membrane] (Homo sapiens)
Kir3.x channels [plasma membrane] (Homo sapiens)
KCNJ5 [plasma membrane] (Homo sapiens)
Kir heterotetramers [plasma membrane] (Homo sapiens)
Kir3 heterotetramer [plasma membrane] (Homo sapiens)
Kir3.x channels [plasma membrane] (Homo sapiens)
KCNJ5 [plasma membrane] (Homo sapiens)
Binding of Gbeta/gamma to GIRK/Kir3 channels (Homo sapiens)
GABA B receptor G-protein beta-gamma and Kir3 channel complex [plasma membrane] (Homo sapiens)
Kir heterotetramers [plasma membrane] (Homo sapiens)
Kir3 heterotetramer [plasma membrane] (Homo sapiens)
Kir3.x channels [plasma membrane] (Homo sapiens)
KCNJ5 [plasma membrane] (Homo sapiens)
Kir heterotetramers [plasma membrane] (Homo sapiens)
Kir3 heterotetramer [plasma membrane] (Homo sapiens)
Kir3.x channels [plasma membrane] (Homo sapiens)
KCNJ5 [plasma membrane] (Homo sapiens)
Transmission across Chemical Synapses (Homo sapiens)
Neurotransmitter receptors and postsynaptic signal transmission (Homo sapiens)
GABA receptor activation (Homo sapiens)
GABA B receptor activation (Homo sapiens)
Activation of GABAB receptors (Homo sapiens)
Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits (Homo sapiens)
Activation of GIRK/Kir3 Channels (Homo sapiens)
GABA B receptor G-protein beta-gamma and Kir3 channel complex [plasma membrane] (Homo sapiens)
Kir heterotetramers [plasma membrane] (Homo sapiens)
Kir3 heterotetramer [plasma membrane] (Homo sapiens)
Kir3.x channels [plasma membrane] (Homo sapiens)
KCNJ5 [plasma membrane] (Homo sapiens)
Kir heterotetramers [plasma membrane] (Homo sapiens)
Kir3 heterotetramer [plasma membrane] (Homo sapiens)
Kir3.x channels [plasma membrane] (Homo sapiens)
KCNJ5 [plasma membrane] (Homo sapiens)
Binding of Gbeta/gamma to GIRK/Kir3 channels (Homo sapiens)
GABA B receptor G-protein beta-gamma and Kir3 channel complex [plasma membrane] (Homo sapiens)
Kir heterotetramers [plasma membrane] (Homo sapiens)
Kir3 heterotetramer [plasma membrane] (Homo sapiens)
Kir3.x channels [plasma membrane] (Homo sapiens)
KCNJ5 [plasma membrane] (Homo sapiens)
Kir heterotetramers [plasma membrane] (Homo sapiens)
Kir3 heterotetramer [plasma membrane] (Homo sapiens)
Kir3.x channels [plasma membrane] (Homo sapiens)
KCNJ5 [plasma membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:P48544 KCNJ5
Gene Names
KCNJ5, GIRK4
Chain
chain:1-419
Reference Genes
BioGPS Gene:3762 KCNJ5
COSMIC (genes):KCNJ5 KCNJ5
CTD Gene:3762 KCNJ5
dbSNP Gene:3762 KCNJ5
ENSEMBL:ENSG00000120457 KCNJ5
ENSEMBL_homo_sapiens_GENE:ENSG00000120457.12 KCNJ5
HGNC:6266 KCNJ5
KEGG Gene (Homo sapiens):3762 KCNJ5
Monarch:3762 KCNJ5
NCBI Gene:3762 KCNJ5
OMIM:600734 KCNJ5
UCSC:P48544 KCNJ5
Reference Transcript
RefSeq:NM_000890.3 KCNJ5
RefSeq:XM_011542810.2 KCNJ5
RefSeq:XM_011542809.2 KCNJ5
Other Identifiers
11736490_at
11752646_a_at
16733397
208397_PM_x_at
208397_x_at
208404_3p_x_at
208404_PM_x_at
208404_x_at
211817_PM_s_at
211817_s_at
237186_PM_at
237186_at
238780_PM_s_at
238780_s_at
3355861
3355862
3355863
3355864
3355865
3355866
3355867
3355868
3355869
3355870
3355871
3355873
3355874
3355875
3355876
3355877
3355879
3666238
3762
76066_at
7945146
91661_at
A_23_P202927
A_24_P309521
A_32_P90812
GE80963
GE830807
GE848911
GO:0003012
GO:0003013
GO:0005215
GO:0005242
GO:0005515
GO:0005886
GO:0006811
GO:0006813
GO:0008076
GO:0015467
GO:0016020
GO:0023052
GO:0034220
GO:0034702
GO:0034765
GO:0055085
GO:0071805
GO:0086089
GO:0086091
GO:0098655
GO:0098914
GO:0098915
GO:0099625
GO:1902282
GO:1990573
HMNXSV003053838
Hs.105438.0.A1_3p_a_at
Hs.161415.0.A1_3p_at
ILMN_1772224
ILMN_2137312
PH_hs_0011378
PH_hs_0021472
TC11001186.hg
TC11002952.hg
U52154_at
g1326052_3p_a_at
g4826799_3p_x_at
Participates
as a member of
Kir3.x channels [plasma membrane] (Homo sapiens)
Inferred To
Homologues of KCNJ5 [plasma membrane]
(Caenorhabditis elegans)
Homologues of KCNJ5 [plasma membrane]
(Drosophila melanogaster)
irk-2 [plasma membrane]
(Caenorhabditis elegans)
KCNJ5 [plasma membrane]
(Bos taurus)
KCNJ5 [plasma membrane]
(Gallus gallus)
KCNJ5 [plasma membrane]
(Sus scrofa)
Kcnj5 [plasma membrane]
(Mus musculus)
Kcnj5 [plasma membrane]
(Rattus norvegicus)
Irk1 [plasma membrane]
(Drosophila melanogaster)
irk-3 [plasma membrane]
(Caenorhabditis elegans)
kcnj5 [plasma membrane]
(Xenopus tropicalis)
Irk3 [plasma membrane]
(Drosophila melanogaster)
irk-1 [plasma membrane]
(Caenorhabditis elegans)
Irk2 [plasma membrane]
(Drosophila melanogaster)
Cross References
RefSeq
XP_011541111.1
,
NP_000881.3
,
XP_011541112.1
Guide to Pharmacology - Targets
437
OpenTargets
ENSG00000120457
HPA
ENSG00000120457-KCNJ5
GeneCards
P48544
Ensembl
ENSP00000434266
,
ENST00000533599
,
ENST00000338350
,
ENST00000529694
,
ENSP00000339960
,
ENSG00000120457
,
ENSP00000433295
PRO
P48544
Pharos - Targets
P48544
Orphanet
19239
HMDB Protein
HMDBP08743
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