Retinoid metabolism and transport

Stable Identifier
R-HSA-975634
Type
Pathway
Species
Homo sapiens
ReviewStatus
5/5
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Retinoid metabolism and transport
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Vitamin A (all-trans-retinol) must be taken up, either as carotenes from plants, or as retinyl esters from animal food. The most prominent carotenes are alpha-carotene, lycopene, lutein, beta-cryptoxanthine, and especially beta-carotene. After uptake they are mostly broken down to retinal. Retinyl esters are hydrolysed like other fats. In enterocytes, retinoids bind to retinol-binding protein (RBP). Transport from enterocytes to the liver happens via chylomicrons (Harrison & Hussain 2001, Harrison 2005).
Literature References
PubMed ID Title Journal Year
16011460 Mechanisms of digestion and absorption of dietary vitamin A

Harrison, EH

Annu Rev Nutr 2005
11340090 Mechanisms involved in the intestinal digestion and absorption of dietary vitamin A

Harrison, EH, Hussain, MM

J Nutr 2001
Participants
Events
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as an event of
Event Information
Go Biological Process
retinoid metabolic process (0001523)
Orthologous Events
Retinoid metabolism and transport (Bos taurus)
Retinoid metabolism and transport (Caenorhabditis elegans)
Retinoid metabolism and transport (Canis familiaris)
Retinoid metabolism and transport (Danio rerio)
Retinoid metabolism and transport (Drosophila melanogaster)
Retinoid metabolism and transport (Gallus gallus)
Retinoid metabolism and transport (Mus musculus)
Retinoid metabolism and transport (Rattus norvegicus)
Retinoid metabolism and transport (Sus scrofa)
Retinoid metabolism and transport (Xenopus tropicalis)
Authored
Jassal, B  (2010-10-01)
Stephan, R  (2010-09-19)
Reviewed
D'Eustachio, P  (2010-11-09)
Blaner, WS  (2013-01-31)
Created
Jassal, B  (2010-10-01)
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