Reactome | MGAT4B [Golgi membrane]

MGAT4B [Golgi membrane]

Stable Identifier

R-HSA-975921

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

Golgi membrane

Synonyms

Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase B, MGT4B_HUMAN

Locations in the PathwayBrowser

Expand all

Disease (Homo sapiens)

- Infectious disease (Homo sapiens)
  - Viral Infection Pathways (Homo sapiens)
    - SARS-CoV Infections (Homo sapiens)
      - SARS-CoV-2 Infection (Homo sapiens)
        
        Late SARS-CoV-2 Infection Events (Homo sapiens)
        
        Translation of Structural Proteins (Homo sapiens)
        
        Maturation of spike protein (Homo sapiens)
        
        Spike trimer glycoside chains get additional branches (Homo sapiens)
        
        MGAT4s [Golgi membrane] (Homo sapiens)
        
        MGAT4B [Golgi membrane] (Homo sapiens)

External Reference Information

External Reference

UniProt:Q9UQ53 MGAT4B

Gene Names

MGAT4B, UNQ906/PRO1927

Chain

chain:1-548

Reference Genes

BioGPS Gene:11282 MGAT4B

COSMIC (genes):MGAT4B MGAT4B

CTD Gene:11282 MGAT4B

dbSNP Gene:11282 MGAT4B

ENSEMBL:ENSG00000161013 MGAT4B

ENSEMBL_homo_sapiens_GENE:ENSG00000161013.17 MGAT4B

ENSEMBL_homo_sapiens_GENE:ENSG00000284501.2 MGAT4B

HGNC:7048 MGAT4B

KEGG Gene (Homo sapiens):11282 MGAT4B

Monarch:11282 MGAT4B

NCBI Gene:11282 MGAT4B

OMIM:604561 MGAT4B

UCSC:Q9UQ53 MGAT4B

Reference Transcript

Other Identifiers

11282

11739184_a_at

11739185_x_at

11744041_s_at

11744042_x_at

11759526_a_at

17003748

220189_PM_s_at

220189_s_at

224598_PM_at

224598_at

2890240

2890241

2890243

2890244

2890245

2890248

2890249

2890251

2890252

2890253

2890255

2890256

2890257

2890259

2890261

2890262

2890264

2890265

2890266

2890267

2890268

2890269

2890270

2890273

2890274

43801_f_at

45788_i_at

45789_f_at

65087_at

8116316

A_21_P0000202

A_33_P3366780

GO:0000139

GO:0003824

GO:0005515

GO:0005783

GO:0005793

GO:0005794

GO:0005795

GO:0006486

GO:0006487

GO:0006491

GO:0008375

GO:0008454

GO:0016020

GO:0016740

GO:0016757

GO:0019082

GO:0036211

GO:0043226

GO:0046872

GO:0140096

GO:1901135

HMNXSV003014283

HMNXSV003043190

ILMN_1722438

ILMN_1796106

ILMN_1809272

PH_hs_0025590

TC05002138.hg

g7710151_3p_a_at

Participates

as a member of

MGAT4s [Golgi membrane] (Homo sapiens)

Inferred To

mgat4bQ9UQ53 [Golgi membrane] (Danio rerio)

Mgat4b [Golgi membrane] (Mus musculus)

Mgat4b [Golgi membrane] (Rattus norvegicus)

Mgat4a [Golgi membrane] (Drosophila melanogaster)

MGAT4B [Golgi membrane] (Bos taurus)

MGAT4B [Golgi membrane] (Canis familiaris)

MGAT4B [Golgi membrane] (Gallus gallus)

MGAT4B [Golgi membrane] (Sus scrofa)

mgat4b [Golgi membrane] (Xenopus tropicalis)

Cross References

RefSeq

NP_055090.1, NP_463459.1

OpenTargets

ENSG00000161013

GeneCards

Q9UQ53

HPA

ENSG00000161013-MGAT4B

Ensembl

ENSP00000491766, ENST00000292591, ENSP00000292591, ENSP00000492708, ENSG00000284501, ENSP00000338487, ENSG00000161013, ENST00000638266, ENST00000639538, ENST00000337755

PRO

Q9UQ53

Pharos - Targets

Q9UQ53

HMDB Protein

HMDBP06337

Interactors (1)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q96CV9 OPTN	5	OPTN [recycling endosome membrane] (R-HSA-8854141) OPTN [Golgi membrane] (R-HSA-2161111) p-S177-OPTN [nucleoplasm] (R-HSA-2562595) p-S177-OPTN [cytosol] (R-HSA-2562525) OPTN [cytosol] (R-HSA-9687907)	0.556	3