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TRIM9 [cytosol]
Stable Identifier
R-HSA-976054
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
E3 ubiquitin-protein ligase TRIM9, TRIM9_HUMAN
Locations in the PathwayBrowser
Expand all
Immune System (Homo sapiens)
Adaptive Immune System (Homo sapiens)
Class I MHC mediated antigen processing & presentation (Homo sapiens)
Antigen processing: Ubiquitination & Proteasome degradation (Homo sapiens)
Interaction of E3 with substrate and E2-Ub complex (Homo sapiens)
Ag-substrate:E3:E2:Ub [cytosol] (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
TRIM9 [cytosol] (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
TRIM9 [cytosol] (Homo sapiens)
Polyubiquitination of substrate (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
TRIM9 [cytosol] (Homo sapiens)
E3:K48-polyubiquitinated substrate [cytosol] (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
TRIM9 [cytosol] (Homo sapiens)
E3:Ub:substrate [cytosol] (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
TRIM9 [cytosol] (Homo sapiens)
Release of E3 from polyubiquitinated substrate (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
TRIM9 [cytosol] (Homo sapiens)
E3:K48-polyubiquitinated substrate [cytosol] (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
TRIM9 [cytosol] (Homo sapiens)
Transfer of Ub from E2 to substrate and release of E2 (Homo sapiens)
Ag-substrate:E3:E2:Ub [cytosol] (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
TRIM9 [cytosol] (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
TRIM9 [cytosol] (Homo sapiens)
E3:Ub:substrate [cytosol] (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
TRIM9 [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q9C026 TRIM9
Gene Names
TRIM9, KIAA0282, RNF91
Chain
chain:1-710
Reference Genes
BioGPS Gene:114088 TRIM9
COSMIC (genes):TRIM9 TRIM9
CTD Gene:114088 TRIM9
dbSNP Gene:114088 TRIM9
ENSEMBL:ENSG00000100505 TRIM9
ENSEMBL:ENSG00000100505.14 TRIM9
HGNC:16288 TRIM9
KEGG Gene (Homo sapiens):114088 TRIM9
Monarch:114088 TRIM9
NCBI Gene:114088 TRIM9
OMIM:606555 TRIM9
UCSC:Q9C026 TRIM9
Reference Transcript
RefSeq:NM_052978.4 TRIM9
RefSeq:XM_017020945.1 TRIM9
RefSeq:XM_011536389.2 TRIM9
RefSeq:NM_015163.5 TRIM9
Other Identifiers
114088
11720617_at
11720618_s_at
11725606_at
16792894
209859_PM_at
209859_at
230280_PM_at
230280_at
3564255
3564256
3564258
3564259
3564260
3564261
3564262
3564270
3564272
3564281
3564282
3564283
3564284
3564285
3564286
3564287
3564288
3564289
3564290
3564291
3564292
3564297
3564298
3564302
3564303
3564328
3564329
3564330
3564331
3564332
3564333
3564334
3564335
3564336
3564337
3564338
3564339
3564340
3564341
3564342
36903_at
56614_at
7979108
A_23_P205632
A_23_P205637
A_24_P321709
A_24_P369656
A_33_P3383836
D87458_at
GE57410
GO:0003824
GO:0005515
GO:0005737
GO:0005856
GO:0008021
GO:0008270
GO:0016567
GO:0016740
GO:0019904
GO:0030163
GO:0030425
GO:0031410
GO:0036211
GO:0042803
GO:0042995
GO:0043161
GO:0043226
GO:0045202
GO:0046872
GO:0061630
GO:0110165
GO:0140096
HMNXSV003015808
HMNXSV003032240
HMNXSV003042122
Hs.23833.0.A1_3p_at
ILMN_1719254
ILMN_1763433
ILMN_1786697
PH_hs_0004274
TC14001127.hg
g12407402_3p_at
Participates
as a candidate of
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
Inferred To
madd-2 [cytosol]
(Caenorhabditis elegans)
trim9 [cytosol]
(Xenopus tropicalis)
TRIM9 [cytosol]
(Bos taurus)
TRIM9 [cytosol]
(Canis familiaris)
TRIM9 [cytosol]
(Danio rerio)
TRIM9 [cytosol]
(Drosophila melanogaster)
TRIM9 [cytosol]
(Gallus gallus)
TRIM9 [cytosol]
(Mus musculus)
TRIM9 [cytosol]
(Rattus norvegicus)
TRIM9 [cytosol]
(Sus scrofa)
Cross References
RefSeq
NP_055978.4
,
XP_011534691.1
,
NP_443210.1
,
XP_016876434.1
OpenTargets
ENSG00000100505
GeneCards
Q9C026
HPA
ENSG00000100505-TRIM9
Ensembl
ENSP00000353561
,
ENST00000360392
,
ENSG00000100505
,
ENSP00000342970
,
ENSP00000298355
,
ENST00000338969
,
ENST00000298355
PRO
Q9C026
Pharos - Targets
Q9C026
PDB
2DB8
,
7B2S
Interactors (6)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q9Y297 BTRC
2
BTRC [cytosol]
(R-HSA-174237)
BTRC [nucleoplasm]
(R-HSA-3361753)
0.781
7
UniProt:Q2TBE0 CWF19L2
1
CWF19L2 [nucleoplasm]
(R-HSA-9770846)
0.718
6
UniProt:P50552 VASP
1
VASP [cytosol]
(R-HSA-446323)
0.666
4
UniProt:P05067 APP
20
APP(18-770) [trans-Golgi network membrane]
(R-HSA-5229136)
APP-C99 [cytosol]
(R-HSA-9617603)
APP(18-770) [extracellular region]
(R-HSA-49335)
APP(18-770) [platelet alpha granule lumen]
(R-HSA-139835)
APP(18-687) [extracellular region]
(R-HSA-9010033)
APP(688-770) [plasma membrane]
(R-HSA-9010028)
APP(18-770) [Golgi lumen]
(R-HSA-8871509)
APP(18-770) [plasma membrane]
(R-HSA-9010038)
APP(18-671) [endosome lumen]
(R-HSA-5693003)
APP(714-770) [endosome lumen]
(R-HSA-6783325)
APP(712-770) [endosome lumen]
(R-HSA-6783331)
APP(672-770) [endosome lumen]
(R-HSA-9010082)
APP(672-713) [endosome lumen]
(R-HSA-5692993)
APP(672-711) [endosome lumen]
(R-HSA-6783333)
APP(18-770) [endosome lumen]
(R-HSA-5229077)
p-APP [endoplasmic reticulum lumen]
(R-HSA-8957012)
APP [endoplasmic reticulum lumen]
(R-HSA-8956696)
APP(672-711) [extracellular region]
(R-HSA-976740)
APP(672-711) [cytosol]
(R-HSA-877188)
APP(672-713) [extracellular region]
(R-HSA-879340)
0.556
3
UniProt:P48730 CSNK1D
3
CSNK1D [nucleoplasm]
(R-HSA-421305)
CSNK1D [endoplasmic reticulum-Golgi intermediate compartment membrane]
(R-HSA-5685717)
CSNK1D [cytosol]
(R-HSA-380315)
0.556
3
UniProt:Q9NV70 EXOC1
2
EXOC1 [plasma membrane]
(R-HSA-2872284)
EXOC1 [cytosol]
(R-HSA-5623375)
0.553
2
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