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LENG1 [nucleoplasm]
Stable Identifier
R-HSA-9769590
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
Leukocyte receptor cluster member 1, LENG1_HUMAN
Locations in the PathwayBrowser for interactor UniProt:Q9BWT7 CAR10
Expand all
Metabolism of RNA (Homo sapiens)
Processing of Capped Intron-Containing Pre-mRNA (Homo sapiens)
mRNA Splicing (Homo sapiens)
mRNA Splicing - Major Pathway (Homo sapiens)
Formation of the Spliceosomal P complex and exon ligation (Homo sapiens)
LENG1 [nucleoplasm] (Homo sapiens)
Spliceosomal P complex dissociates yielding the intron-containing complex (ILS) and the spliced mRNP (new) (Homo sapiens)
LENG1 [nucleoplasm] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q96BZ8 LENG1
Gene Names
LENG1
Chain
chain:1-264
Reference Genes
BioGPS Gene:79165 LENG1
COSMIC (genes):LENG1 LENG1
CTD Gene:79165 LENG1
dbSNP Gene:79165 LENG1
ENSEMBL:ENSG00000105617 LENG1
ENSEMBL_homo_sapiens_GENE:ENSG00000105617.4 LENG1
ENSEMBL_homo_sapiens_GENE:ENSG00000275935.1 LENG1
ENSEMBL_homo_sapiens_GENE:ENSG00000276628.1 LENG1
ENSEMBL_homo_sapiens_GENE:ENSG00000276774.1 LENG1
ENSEMBL_homo_sapiens_GENE:ENSG00000276959.1 LENG1
ENSEMBL_homo_sapiens_GENE:ENSG00000277457.1 LENG1
ENSEMBL_homo_sapiens_GENE:ENSG00000277808.1 LENG1
ENSEMBL_homo_sapiens_GENE:ENSG00000278257.1 LENG1
ENSEMBL_homo_sapiens_GENE:ENSG00000278426.1 LENG1
ENSEMBL_homo_sapiens_GENE:ENSG00000278516.1 LENG1
HGNC:15502 LENG1
KEGG Gene (Homo sapiens):79165 LENG1
Monarch:79165 LENG1
NCBI Gene:79165 LENG1
UCSC:Q96BZ8 LENG1
Reference Transcript
RefSeq:NM_024316.2 LENG1
Other Identifiers
11734157_a_at
16875290
232018_PM_at
232018_at
3870521
3870522
3870523
3870524
3870525
3870526
3870527
79165
8039139
84668_at
A_23_P208523
GE530373
GO:0003674
GO:0005515
GO:0005575
GO:0005634
GO:0005654
GO:0008150
GO:0043226
HMNXSV003054694
Hs.172407.0.S1_3p_at
ILMN_1679238
TC19001835.hg
Participates
as an input of
Formation of the Spliceosomal P complex and exon ligation (Homo sapiens)
as an output of
Spliceosomal P complex dissociates yielding the intron-containing complex (ILS) and the spliced mRNP (new) (Homo sapiens)
as a component of
Spliceosomal P complex [nucleoplasm] (Homo sapiens)
Inferred To
LENG1 [nucleoplasm]
(Bos taurus)
LENG1 [nucleoplasm]
(Caenorhabditis elegans)
LENG1 [nucleoplasm]
(Canis familiaris)
LENG1 [nucleoplasm]
(Dictyostelium discoideum)
LENG1 [nucleoplasm]
(Sus scrofa)
leng1 [nucleoplasm]
(Danio rerio)
leng1 [nucleoplasm]
(Xenopus tropicalis)
Dmel\CG12818 [nucleoplasm]
(Drosophila melanogaster)
Leng1 [nucleoplasm]
(Mus musculus)
Leng1 [nucleoplasm]
(Rattus norvegicus)
Ghost homologue of LENG1 [nucleoplasm]
(Gallus gallus)
Ghost homologue of LENG1 [nucleoplasm]
(Plasmodium falciparum)
Ghost homologue of LENG1 [nucleoplasm]
(Schizosaccharomyces pombe)
Cross References
RefSeq
NP_077292.2
OpenTargets
ENSG00000105617
HPA
ENSG00000105617-LENG1
GeneCards
Q96BZ8
Ensembl
ENSG00000276959
,
ENST00000617592
,
ENSG00000277457
,
ENST00000616103
,
ENSG00000276774
,
ENSG00000277808
,
ENST00000621285
,
ENSP00000481252
,
ENSP00000222224
,
ENST00000614037
,
ENST00000619669
,
ENST00000222224
,
ENST00000616816
,
ENSP00000481079
,
ENST00000613622
,
ENST00000610998
,
ENSP00000477607
,
ENSG00000278257
,
ENSG00000278516
,
ENST00000621927
,
ENSG00000276628
,
ENSG00000275935
,
ENSP00000483164
,
ENSP00000481386
,
ENSP00000479538
,
ENSP00000480516
,
ENSP00000478485
,
ENSP00000481948
,
ENSG00000278426
,
ENSG00000105617
PRO
Q96BZ8
Pharos - Targets
Q96BZ8
Interactors (88)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q08379 GOLGA2
3
p-S37-GOLGA2 [Golgi membrane]
(R-HSA-2172179)
GOLGA2 [endoplasmic reticulum-Golgi intermediate compartment membrane]
(R-HSA-2167933)
GOLGA2 [Golgi membrane]
(R-HSA-6808764)
0.795
8
UniProt:Q8NHQ1 CEP70
1
CEP70 [cytosol]
(R-HSA-380257)
0.781
7
UniProt:O95751 LDOC1
0.781
8
UniProt:Q9HAT0 ROPN1
1
ROPN1 [cytosol]
(R-HSA-5667048)
0.781
8
UniProt:Q9UJV3-2 MID2
0.718
6
UniProt:Q15323 KRT31
1
KRT31 [cytosol]
(R-HSA-6809616)
0.718
6
UniProt:Q01850 CDR2
0.718
6
UniProt:A1L4K1 FSD2
0.718
6
UniProt:Q9BYV2 TRI54
0.718
6
UniProt:Q6A162 KRT40
1
KRT40 [cytosol]
(R-HSA-6809605)
0.718
6
UniProt:Q15742 NAB2
1
NAB2 [nucleoplasm]
(R-HSA-9612177)
0.718
6
UniProt:Q04864-2 REL
0.666
4
UniProt:Q8N9N5 BANP
1
BANP [nucleoplasm]
(R-HSA-3221973)
0.666
4
UniProt:P61970 NTF2
0.556
3
UniProt:Q9Y250 LZTS1
0.556
3
UniProt:Q92764 KRT35
1
KRT35 [cytosol]
(R-HSA-6809595)
0.556
3
UniProt:Q8WW34 TM239
0.556
3
UniProt:P31321 PRKAR1B
2
PRKAR1B [cytosol]
(R-HSA-57838)
PRKAR1B [ciliary base]
(R-HSA-5610409)
0.556
3
UniProt:Q8TD31-3 CCHCR1
0.556
3
UniProt:Q96KG9-4 SCYL1
0.556
3
UniProt:Q9BXU0 TEX12
1
TEX12 [nucleoplasm]
(R-HSA-912441)
0.556
3
UniProt:Q96D03 DDT4L
0.556
3
UniProt:Q9H0C1 ZMY12
0.556
3
UniProt:P17661 DES
1
DES [cytosol]
(R-HSA-390570)
0.556
3
UniProt:Q9H257-2 CARD9
0.556
3
UniProt:Q13137 CACO2
0.556
3
UniProt:Q5JR59-3 MTUS2
0.556
3
UniProt:Q8WXK4-2 Q8WXK42
0.556
3
UniProt:Q5VU43 MYOME
0.556
3
UniProt:Q9P2M1 LR2BP
0.556
3
UniProt:Q9NRI5-2 DISC1
0.556
3
UniProt:Q68D86 C102B
0.556
3
UniProt:Q9P286 PAK5
2
PAK7 [plasma membrane]
(R-HSA-211555)
PAK5 [cytosol]
(R-HSA-428459)
0.556
3
UniProt:Q9ULR0-1 Q9ULR01
0.556
3
UniProt:Q96ED9-2 HOOK2
0.556
3
IntAct:EBI-16436244 CCSB ORF ID
0.556
3
UniProt:Q5T124-6 UBXN11
0.556
3
UniProt:Q96HA8 NTAQ1
0.556
3
UniProt:P41219 PERI
0.556
3
UniProt:Q9NWQ9 CN119
0.556
3
UniProt:Q13084 MRPL28
1
MRPL28 [mitochondrial inner membrane]
(R-HSA-5368246)
0.556
3
UniProt:Q7Z6G3-2 NECAB2
0.556
3
UniProt:O75558 STX11
0.556
3
UniProt:Q99687-3 Q996873
0.556
3
UniProt:Q2TAC2-2 CCDC57
0.556
3
UniProt:Q9BWT7 CAR10
0.556
3
UniProt:Q86X02 CDR2L
0.556
3
UniProt:Q8IYX8-2 CEP57L1
0.556
3
UniProt:Q8TD10 MIPO1
0.556
3
UniProt:Q8N8X9 MB213
0.556
3
UniProt:Q9UKT9 IKZF3
0.556
3
UniProt:Q8N6L0 KASH5
0.556
3
UniProt:Q8N6Y0 USBP1
0.556
3
UniProt:Q9Y6D9 MAD1L1
1
MAD1L1 [cytosol]
(R-HSA-141433)
0.556
3
UniProt:Q9BVG8 KIFC3
0.556
3
UniProt:Q15276 RABEP1
1
RABEP1 [early endosome membrane]
(R-HSA-2029004)
0.556
3
UniProt:Q96JN2-2 CCDC136
0.556
3
UniProt:P15884 TCF4
1
TCF4 [nucleoplasm]
(R-HSA-445672)
0.556
3
UniProt:P60410 KRTAP10-8
1
KRTAP10-8 [cytosol]
(R-HSA-6810301)
0.556
3
UniProt:O60447 EVI5
0.556
3
UniProt:Q63ZY3 KANK2
0.556
3
UniProt:P36406 TRI23
0.556
3
IntAct:EBI-16435328 CCSB ORF ID
0.556
3
UniProt:Q5JR59 MTUS2
0.556
3
UniProt:Q96N21 AP4AT
0.556
3
UniProt:Q8NA61 CBY2
0.556
3
UniProt:Q86WV8 Q86WV8
0.556
3
UniProt:A6NEM1 GG6L9
0.556
3
UniProt:Q9BVG8-5 KIFC3
0.556
3
UniProt:Q2TAC2 CCD57
0.556
3
UniProt:O43482 OIP5
1
OIP5 [nucleoplasm]
(R-HSA-606286)
0.556
3
UniProt:P08727 KRT19
1
KRT19 [cytosol]
(R-HSA-6809617)
0.556
3
UniProt:Q9NYB9-2 ABI2
0.556
3
UniProt:Q96RU7 TRIB3
3
TRIB3 [plasma membrane]
(R-HSA-199447)
TRIB3 [cytosol]
(R-HSA-162411)
TRIB3 [nucleoplasm]
(R-HSA-9635877)
0.556
3
UniProt:P14373 TRIM27
2
TRIM27 [nucleoplasm]
(R-HSA-2997690)
TRIM27 [cytosol]
(R-HSA-8851002)
0.556
3
UniProt:Q9BZL1 UBL5
1
UBL5 [nucleoplasm]
(R-HSA-9770255)
0.556
3
UniProt:Q9UM82 SPATA2
1
SPATA2 [cytosol]
(R-HSA-9796351)
0.556
3
UniProt:Q9H257 CARD9
3
CARD9 [cytosol]
(R-HSA-561194)
CARD9 [plasma membrane]
(R-HSA-5607662)
p-T231-CARD9 [plasma membrane]
(R-HSA-5607623)
0.556
3
UniProt:Q12933 TRAF2
5
TRAF2 [nucleoplasm]
(R-HSA-8862199)
K63polyUb-TRAF2 [nucleoplasm]
(R-HSA-8862194)
K63polyUb-TRAF2 [cytosol]
(R-HSA-8862193)
PolyUb-TRAF2 [cytosol]
(R-HSA-6782848)
TRAF2 [cytosol]
(R-HSA-66370)
0.556
3
UniProt:Q9UBB9 TFIP11
1
TFIP11 [nucleoplasm]
(R-HSA-8869310)
0.556
3
UniProt:Q9UGI0 ZRANB1
1
ZRANB1 [cytosol]
(R-HSA-6781939)
0.556
3
UniProt:Q9BUH8 BEGAIN
1
BEGAIN [cytosol]
(R-HSA-6794250)
0.556
3
UniProt:P20618 PSMB1
7
PSMB1(1-28) [cytosol]
(R-HSA-9908143)
pro-PSMB1 [cytosol]
(R-HSA-9908139)
PSMB1 [secretory granule lumen]
(R-HSA-6803287)
PSMB1 [extracellular region]
(R-HSA-6806477)
PSMB1 [ficolin-1-rich granule lumen]
(R-HSA-6803340)
PSMB1 [nucleoplasm]
(R-HSA-174347)
PSMB1 [cytosol]
(R-HSA-68738)
0.556
3
UniProt:P14136 GFAP
3
p-GFAP [lysosomal membrane]
(R-HSA-9626054)
GFAP [lysosomal membrane]
(R-HSA-9625195)
GFAP [cytosol]
(R-HSA-1253311)
0.556
3
UniProt:Q6AZZ1 TRIM68
1
TRIM68 [cytosol]
(R-HSA-5624350)
0.527
2
UniProt:Q96DF8 ESS2
0.527
2
UniProt:O95619 YEATS4
1
YEATS4 [nucleoplasm]
(R-HSA-3322940)
0.527
2
UniProt:P14079 TAX
0.488
2
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