Reactome | LENG1 [nucleoplasm]

LENG1 [nucleoplasm]

Stable Identifier

R-HSA-9769590

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

Leukocyte receptor cluster member 1, LENG1_HUMAN

Locations in the PathwayBrowser for interactor UniProt:Q9P2M1 LR2BP

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External Reference Information

External Reference

UniProt:Q96BZ8 LENG1

Gene Names

LENG1

Chain

chain:1-264

Reference Genes

BioGPS Gene:79165 LENG1

COSMIC (genes):LENG1 LENG1

CTD Gene:79165 LENG1

dbSNP Gene:79165 LENG1

ENSEMBL:ENSG00000105617 LENG1

HGNC:15502 LENG1

KEGG:hsa:79165 LENG1

Monarch:79165 LENG1

NCBI Gene:79165 LENG1

UCSC:Q96BZ8 LENG1

Reference Transcript

RefSeq:NM_024316.2 LENG1

Other Identifiers

11734157_a_at

16875290

232018_PM_at

232018_at

3870521

3870522

3870523

3870524

3870525

3870526

3870527

79165

8039139

84668_at

A_23_P208523

GE530373

GO:0003674

GO:0005515

GO:0005575

GO:0005654

GO:0008150

HMNXSV003054694

Hs.172407.0.S1_3p_at

ILMN_1679238

TC19001835.hg

Participates

as an input of

Formation of the Spliceosomal P complex and exon ligation (Homo sapiens)

as an output of

Spliceosomal P complex dissociates yielding the intron-containing complex (ILS) and the spliced mRNP (new) (Homo sapiens)

as a component of

Spliceosomal P complex [nucleoplasm] (Homo sapiens)

Inferred To

LENG1 [nucleoplasm] (Bos taurus)

LENG1 [nucleoplasm] (Caenorhabditis elegans)

LENG1 [nucleoplasm] (Canis familiaris)

LENG1 [nucleoplasm] (Dictyostelium discoideum)

LENG1 [nucleoplasm] (Sus scrofa)

leng1 [nucleoplasm] (Danio rerio)

leng1 [nucleoplasm] (Xenopus tropicalis)

Dmel\CG12818 [nucleoplasm] (Drosophila melanogaster)

Leng1 [nucleoplasm] (Mus musculus)

Leng1 [nucleoplasm] (Rattus norvegicus)

Ghost homologue of LENG1 [nucleoplasm] (Gallus gallus)

Ghost homologue of LENG1 [nucleoplasm] (Plasmodium falciparum)

Ghost homologue of LENG1 [nucleoplasm] (Schizosaccharomyces pombe)

Cross References

RefSeq

NP_077292.2

OpenTargets

ENSG00000105617

ENSEMBL

ENST00000613622, ENSP00000483164, ENSP00000481079, ENSP00000481386, ENST00000621927, ENST00000222224, ENSP00000481252, ENST00000619669, ENSP00000222224, ENST00000616816, ENST00000614037, ENSP00000479538, ENST00000610998, ENSP00000481948, ENST00000617592, ENSP00000477607, ENST00000621285, ENST00000616103, ENSP00000478485, ENSP00000480516

HPA

ENSG00000105617-LENG1

PRO

Q96BZ8

Pharos - Targets

Q96BZ8

GlyGen

Q96BZ8

Interactors (88)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q08379 GOLGA2	3	p-S37-GOLGA2 [Golgi membrane] (R-HSA-2172179) GOLGA2 [endoplasmic reticulum-Golgi intermediate compartment membrane] (R-HSA-2167933) GOLGA2 [Golgi membrane] (R-HSA-6808764)	0.795	8
UniProt:Q9HAT0 ROPN1	1	ROPN1 [cytosol] (R-HSA-5667048)	0.781	8
UniProt:O95751 LDOC1			0.781	8
UniProt:Q8NHQ1 CEP70	1	CEP70 [cytosol] (R-HSA-380257)	0.781	7
UniProt:Q15742 NAB2	1	NAB2 [nucleoplasm] (R-HSA-9612177)	0.718	6
UniProt:Q6A162 KRT40	1	KRT40 [cytosol] (R-HSA-6809605)	0.718	6
UniProt:Q9BYV2 TRI54			0.718	6
UniProt:A1L4K1 FSD2			0.718	6
UniProt:Q01850 CDR2			0.718	6
UniProt:Q15323 KRT31	1	KRT31 [cytosol] (R-HSA-6809616)	0.718	6
UniProt:Q9UJV3-2 MID2			0.718	6
UniProt:Q04864-2 REL			0.666	4
UniProt:Q8N9N5 BANP	1	BANP [nucleoplasm] (R-HSA-3221973)	0.666	4
UniProt:P61970 NTF2			0.556	3
UniProt:Q9Y250 LZTS1			0.556	3
UniProt:Q92764 KRT35	1	KRT35 [cytosol] (R-HSA-6809595)	0.556	3
UniProt:Q8WW34 TM239			0.556	3
UniProt:P31321 PRKAR1B	2	PRKAR1B [cytosol] (R-HSA-57838) PRKAR1B [ciliary base] (R-HSA-5610409)	0.556	3
UniProt:Q8TD31-3 CCHCR1			0.556	3
UniProt:Q96KG9-4 SCYL1			0.556	3
UniProt:Q9BXU0 TEX12	1	TEX12 [nucleoplasm] (R-HSA-912441)	0.556	3
UniProt:Q96D03 DDT4L			0.556	3
UniProt:Q9H0C1 ZMY12			0.556	3
UniProt:P17661 DES	1	DES [cytosol] (R-HSA-390570)	0.556	3
UniProt:Q9H257-2 CARD9			0.556	3
UniProt:Q9BZL1 UBL5	1	UBL5 [nucleoplasm] (R-HSA-9770255)	0.556	3
UniProt:Q13137 CACO2			0.556	3
UniProt:P20618 PSMB1	7	PSMB1 [cytosol] (R-HSA-68738) PSMB1 [nucleoplasm] (R-HSA-174347) PSMB1 [secretory granule lumen] (R-HSA-6803287) PSMB1 [extracellular region] (R-HSA-6806477) PSMB1 [ficolin-1-rich granule lumen] (R-HSA-6803340) pro-PSMB1 [cytosol] (R-HSA-9908139) PSMB1(1-28) [cytosol] (R-HSA-9908143)	0.556	3
UniProt:P14136 GFAP	3	p-GFAP [lysosomal membrane] (R-HSA-9626054) GFAP [lysosomal membrane] (R-HSA-9625195) GFAP [cytosol] (R-HSA-1253311)	0.556	3
UniProt:Q5JR59-3 MTUS2			0.556	3
UniProt:Q8WXK4-2 Q8WXK42			0.556	3
UniProt:Q96RU7 TRIB3	3	TRIB3 [plasma membrane] (R-HSA-199447) TRIB3 [cytosol] (R-HSA-162411) TRIB3 [nucleoplasm] (R-HSA-9635877)	0.556	3
UniProt:Q5VU43 MYOME			0.556	3
UniProt:Q9P2M1 LR2BP			0.556	3
UniProt:Q9NRI5-2 DISC1			0.556	3
UniProt:Q68D86 C102B			0.556	3
UniProt:Q9P286 PAK5	2	PAK5 [cytosol] (R-HSA-428459) PAK7 [plasma membrane] (R-HSA-211555)	0.556	3
UniProt:Q9ULR0-1 Q9ULR01			0.556	3
UniProt:Q96ED9-2 HOOK2			0.556	3
IntAct:EBI-16436244 CCSB ORF ID			0.556	3
UniProt:Q5T124-6 UBXN11			0.556	3
UniProt:Q96HA8 NTAQ1			0.556	3
UniProt:P41219 PERI			0.556	3
UniProt:Q9H257 CARD9	3	CARD9 [cytosol] (R-HSA-561194) p-T231-CARD9 [plasma membrane] (R-HSA-5607623) CARD9 [plasma membrane] (R-HSA-5607662)	0.556	3
UniProt:Q9NWQ9 CN119			0.556	3
UniProt:Q13084 MRPL28	1	MRPL28 [mitochondrial inner membrane] (R-HSA-5368246)	0.556	3
UniProt:Q9UM82 SPATA2	1	SPATA2 [cytosol] (R-HSA-9796351)	0.556	3
UniProt:Q7Z6G3-2 NECAB2			0.556	3
UniProt:O75558 STX11			0.556	3
UniProt:Q99687-3 Q996873			0.556	3
UniProt:Q2TAC2-2 CCDC57			0.556	3
UniProt:Q9BWT7 CAR10			0.556	3
UniProt:Q86X02 CDR2L			0.556	3
UniProt:Q12933 TRAF2	5	TRAF2 [cytosol] (R-HSA-66370) PolyUb-TRAF2 [cytosol] (R-HSA-6782848) K63polyUb-TRAF2 [cytosol] (R-HSA-8862193) K63polyUb-TRAF2 [nucleoplasm] (R-HSA-8862194) TRAF2 [nucleoplasm] (R-HSA-8862199)	0.556	3
UniProt:Q9UGI0 ZRANB1	1	ZRANB1 [cytosol] (R-HSA-6781939)	0.556	3
UniProt:Q9NYB9-2 ABI2			0.556	3
UniProt:P08727 KRT19	1	KRT19 [cytosol] (R-HSA-6809617)	0.556	3
UniProt:O43482 OIP5	1	OIP5 [nucleoplasm] (R-HSA-606286)	0.556	3
UniProt:Q2TAC2 CCD57			0.556	3
UniProt:Q9BVG8-5 KIFC3			0.556	3
UniProt:A6NEM1 GG6L9			0.556	3
UniProt:Q86WV8 Q86WV8			0.556	3
UniProt:Q8NA61 CBY2			0.556	3
UniProt:Q96N21 AP4AT			0.556	3
UniProt:Q5JR59 MTUS2			0.556	3
IntAct:EBI-16435328 CCSB ORF ID			0.556	3
UniProt:P36406 TRI23			0.556	3
UniProt:Q63ZY3 KANK2			0.556	3
UniProt:O60447 EVI5			0.556	3
UniProt:P60410 KRTAP10-8	1	KRTAP10-8 [cytosol] (R-HSA-6810301)	0.556	3
UniProt:P15884 TCF4	1	TCF4 [nucleoplasm] (R-HSA-445672)	0.556	3
UniProt:Q96JN2-2 CCDC136			0.556	3
UniProt:Q15276 RABEP1	1	RABEP1 [early endosome membrane] (R-HSA-2029004)	0.556	3
UniProt:Q9BVG8 KIFC3			0.556	3
UniProt:Q9Y6D9 MAD1L1	1	MAD1L1 [cytosol] (R-HSA-141433)	0.556	3
UniProt:Q8N6Y0 USBP1			0.556	3
UniProt:Q8N6L0 KASH5			0.556	3
UniProt:Q9UKT9 IKZF3			0.556	3
UniProt:Q9BUH8 BEGAIN	1	BEGAIN [cytosol] (R-HSA-6794250)	0.556	3
UniProt:Q8N8X9 MB213			0.556	3
UniProt:P14373 TRIM27	2	TRIM27 [cytosol] (R-HSA-8851002) TRIM27 [nucleoplasm] (R-HSA-2997690)	0.556	3
UniProt:Q8TD10 MIPO1			0.556	3
UniProt:Q8IYX8-2 CEP57L1			0.556	3
UniProt:Q9UBB9 TFIP11	1	TFIP11 [nucleoplasm] (R-HSA-8869310)	0.556	3
UniProt:Q6AZZ1 TRIM68	1	TRIM68 [cytosol] (R-HSA-5624350)	0.527	2
UniProt:O95619 YEATS4	1	YEATS4 [nucleoplasm] (R-HSA-3322940)	0.527	2
UniProt:Q96DF8 ESS2			0.527	2
UniProt:P14079 TAX			0.488	2

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